ID   E3HT68_ACHXA            Unreviewed;       509 AA.
AC   E3HT68;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Acetaldehyde dehydrogenase {ECO:0000313|EMBL:ADP13694.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:ADP13694.1};
GN   Name=aldB {ECO:0000313|EMBL:ADP13694.1};
GN   OrderedLocusNames=AXYL_00335 {ECO:0000313|EMBL:ADP13694.1};
OS   Achromobacter xylosoxidans (strain A8).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Achromobacter.
OX   NCBI_TaxID=762376 {ECO:0000313|EMBL:ADP13694.1, ECO:0000313|Proteomes:UP000006876};
RN   [1] {ECO:0000313|EMBL:ADP13694.1, ECO:0000313|Proteomes:UP000006876}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A8 {ECO:0000313|EMBL:ADP13694.1,
RC   ECO:0000313|Proteomes:UP000006876};
RX   PubMed=21097610; DOI=10.1128/JB.01299-10;
RA   Strnad H., Ridl J., Paces J., Kolar M., Vlcek C., Paces V.;
RT   "Complete genome sequence of the haloaromatic acids-degrading bacterium
RT   Achromobacter xylosoxidans A8.";
RL   J. Bacteriol. 193:791-792(2011).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP002287; ADP13694.1; -; Genomic_DNA.
DR   RefSeq; WP_013391092.1; NC_014640.1.
DR   AlphaFoldDB; E3HT68; -.
DR   STRING; 762376.AXYL_00335; -.
DR   KEGG; axy:AXYL_00335; -.
DR   PATRIC; fig|762376.5.peg.334; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_0_0_4; -.
DR   OrthoDB; 6187633at2; -.
DR   Proteomes; UP000006876; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07116; ALDH_ACDHII-AcoD; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR43111; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR   PANTHER; PTHR43111:SF1; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          30..496
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        265
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   509 AA;  55738 MW;  8AD0BE12C3782652 CRC64;
     MDIATRITPD SYGTRLDLKT QYDNFIDGKW QKPADGEYFD NVTPVTGQVL TRNARSKERD
     IELALDAAHR AAPKWGATPA AQRAHMLMQI ADVMEANLER LATAETWDNG KPIREARAAD
     IPLAIDHFRY FASCIRSQEG GLSEIDSDTV AYHFNEPLGV VGQIIPWNFP ILMAAWKLAP
     ALAAGNCVVL KPAEQTPLGI LLLMELIGDI LPAGVINVVT GFGLEAGKPL ASNKRIAKIA
     FTGETTTGRL IMQYASQNII PVTLELGGKS PNIFFADVAA QDDDFLDKAV EGFVMFALNQ
     GEVCTCPSRA LIQESLYDKF MERALKRVAE IKQGNPLDAD TMLGAQASTE QLEKILSYLD
     IGKQEGADVL AGGSRAQMQG ALEGGYYVQP TVFKGHNKMR VFQEEIFGPV VAVTTFKDAD
     DALALANDTL YGLGAGVWSR DANTCYRMGR AIKAGRVWTN CYHAYPAHAA FGGYKQSGIG
     RENHKMMLNH YQQTKNLLVS YSPKKLGFF
//