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E3HJW2

- E3HJW2_ACHXA

UniProt

E3HJW2 - E3HJW2_ACHXA

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Protein

Threonine--tRNA ligase

Gene
thrS, AXYL_02262
Organism
Achromobacter xylosoxidans (strain A8)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).UniRule annotationSAAS annotations

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi338 – 3381Zinc; catalytic By similarityUniRule annotation
Metal bindingi389 – 3891Zinc; catalytic By similarityUniRule annotation
Metal bindingi515 – 5151Zinc; catalytic By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW
  3. threonine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. threonyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotationsImported, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAXYL762376:GJUB-2262-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Threonine--tRNA ligaseUniRule annotation (EC:6.1.1.3UniRule annotation)
Alternative name(s):
Threonyl-tRNA synthetase
Gene namesi
Name:thrSUniRule annotationImported
Ordered Locus Names:AXYL_02262Imported
OrganismiAchromobacter xylosoxidans (strain A8)Imported
Taxonomic identifieri762376 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeAchromobacter
ProteomesiUP000006876: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni247 – 538292Catalytic By similarityUniRule annotationAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000003880.
KOiK01868.
OMAiHFKLQKI.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
3.40.50.800. 1 hit.
HAMAPiMF_00184. Thr_tRNA_synth.
InterProiIPR002314. aa-tRNA-synt_IIb_cons-dom.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR012675. Beta-grasp_dom.
IPR004095. TGS.
IPR012676. TGS-like.
IPR002320. Thr-tRNA-ligase_IIa.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
IPR012947. tRNA_SAD.
[Graphical view]
PfamiPF03129. HGTP_anticodon. 1 hit.
PF02824. TGS. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view]
PRINTSiPR01047. TRNASYNTHTHR.
SMARTiSM00863. tRNA_SAD. 1 hit.
[Graphical view]
SUPFAMiSSF52954. SSF52954. 1 hit.
SSF55186. SSF55186. 1 hit.
SSF81271. SSF81271. 1 hit.
TIGRFAMsiTIGR00418. thrS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3HJW2-1 [UniParc]FASTAAdd to Basket

« Hide

MVQITLPDGS QRQYPGPVTV AEVAQSIGTG LAKAALGGRV TFEGSDSKLV    50
DTSFRIEGDA RLAIVTAKDA DGLDLIRHST AHLLAYAVKE LFPDAQVTIG 100
PVIDNGFYYD FSYKRPFTPE DLAAIEKKMA ELAKKDEVVT REEWSRDDAV 150
EFFKGIGEKY KAEIIASIPS NEPLSLYREG DFIDLCRGPH VPSTGKLKVF 200
KLMKVAGAYW RGDSKNEMLQ RIYGTAWATK EEQEAYLHML EEAERRDHRK 250
IGRELELFHF QDEAPGLIFW HPKGWALWQQ VEQYMRSVYR DNGYQEVKAP 300
QILDISLWKK TGHWDNYREN MFTTESENRV YGLKPMNCPG HVQIFNAGLH 350
SYRELPLRYG EFGQCHRNEP SGSLHGMMRV RGFTQDDGHI FCTEEQLQDE 400
CADFTALLQK VYRDFGFTEV LYKVATRPEK RIGSDEVWDT AEAALMESLR 450
RTGCEFEVSP GEGAFYGPKV EYTLKDAIGR HWQCGTIQVD FSMPVRLGAE 500
YVDQNDQRRP PVMLHRAILG SLERFIGMLI ENHAGAMPPW LAPVQAVVCC 550
ISEPSADYAA EITQSLKKQG FRVESDLRGE KITRKIREHS LQKVPYILVV 600
GDKEKQNGTV AVRGLGGLDL GAIAYDEFVA RLSEDVSTRR DVNQPGSSAA 650
Length:650
Mass (Da):73,415
Last modified:January 11, 2011 - v1
Checksum:i7AB89A90CE298D7E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002287 Genomic DNA. Translation: ADP15584.1.
RefSeqiWP_013392910.1. NC_014640.1.
YP_003978299.1. NC_014640.1.

Genome annotation databases

EnsemblBacteriaiADP15584; ADP15584; AXYL_02262.
GeneIDi9896594.
KEGGiaxy:AXYL_02262.
PATRICi42557550. VBIAchXyl160325_2255.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002287 Genomic DNA. Translation: ADP15584.1 .
RefSeqi WP_013392910.1. NC_014640.1.
YP_003978299.1. NC_014640.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADP15584 ; ADP15584 ; AXYL_02262 .
GeneIDi 9896594.
KEGGi axy:AXYL_02262.
PATRICi 42557550. VBIAchXyl160325_2255.

Phylogenomic databases

HOGENOMi HOG000003880.
KOi K01868.
OMAi HFKLQKI.

Enzyme and pathway databases

BioCyci AXYL762376:GJUB-2262-MONOMER.

Family and domain databases

Gene3Di 3.10.20.30. 1 hit.
3.40.50.800. 1 hit.
HAMAPi MF_00184. Thr_tRNA_synth.
InterProi IPR002314. aa-tRNA-synt_IIb_cons-dom.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR012675. Beta-grasp_dom.
IPR004095. TGS.
IPR012676. TGS-like.
IPR002320. Thr-tRNA-ligase_IIa.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
IPR012947. tRNA_SAD.
[Graphical view ]
Pfami PF03129. HGTP_anticodon. 1 hit.
PF02824. TGS. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view ]
PRINTSi PR01047. TRNASYNTHTHR.
SMARTi SM00863. tRNA_SAD. 1 hit.
[Graphical view ]
SUPFAMi SSF52954. SSF52954. 1 hit.
SSF55186. SSF55186. 1 hit.
SSF81271. SSF81271. 1 hit.
TIGRFAMsi TIGR00418. thrS. 1 hit.
PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the haloaromatic acid-degrading bacterium Achromobacter xylosoxidans A8."
    Strnad H., Ridl J., Paces J., Kolar M., Vlcek C., Paces V.
    J. Bacteriol. 193:791-792(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A8Imported.

Entry informationi

Entry nameiE3HJW2_ACHXA
AccessioniPrimary (citable) accession number: E3HJW2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: September 3, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi