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E3HJW2 (E3HJW2_ACHXA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Threonine--tRNA ligase HAMAP-Rule MF_00184

EC=6.1.1.3 HAMAP-Rule MF_00184
Alternative name(s):
Threonyl-tRNA synthetase HAMAP-Rule MF_00184
Gene names
Name:thrS HAMAP-Rule MF_00184 EMBL ADP15584.1
Ordered Locus Names:AXYL_02262 EMBL ADP15584.1
OrganismAchromobacter xylosoxidans (strain A8) [Complete proteome] [HAMAP] EMBL ADP15584.1
Taxonomic identifier762376 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeAchromobacter

Protein attributes

Sequence length650 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr). HAMAP-Rule MF_00184 SAAS SAAS004095

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00184 SAAS SAAS004095

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00184

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00184 SAAS SAAS004095.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00184 RuleBase RU003746

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region247 – 538292Catalytic By similarity HAMAP-Rule MF_00184

Sites

Metal binding3381Zinc; catalytic By similarity HAMAP-Rule MF_00184
Metal binding3891Zinc; catalytic By similarity HAMAP-Rule MF_00184
Metal binding5151Zinc; catalytic By similarity HAMAP-Rule MF_00184

Sequences

Sequence LengthMass (Da)Tools
E3HJW2 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 7AB89A90CE298D7E

FASTA65073,415
        10         20         30         40         50         60 
MVQITLPDGS QRQYPGPVTV AEVAQSIGTG LAKAALGGRV TFEGSDSKLV DTSFRIEGDA 

        70         80         90        100        110        120 
RLAIVTAKDA DGLDLIRHST AHLLAYAVKE LFPDAQVTIG PVIDNGFYYD FSYKRPFTPE 

       130        140        150        160        170        180 
DLAAIEKKMA ELAKKDEVVT REEWSRDDAV EFFKGIGEKY KAEIIASIPS NEPLSLYREG 

       190        200        210        220        230        240 
DFIDLCRGPH VPSTGKLKVF KLMKVAGAYW RGDSKNEMLQ RIYGTAWATK EEQEAYLHML 

       250        260        270        280        290        300 
EEAERRDHRK IGRELELFHF QDEAPGLIFW HPKGWALWQQ VEQYMRSVYR DNGYQEVKAP 

       310        320        330        340        350        360 
QILDISLWKK TGHWDNYREN MFTTESENRV YGLKPMNCPG HVQIFNAGLH SYRELPLRYG 

       370        380        390        400        410        420 
EFGQCHRNEP SGSLHGMMRV RGFTQDDGHI FCTEEQLQDE CADFTALLQK VYRDFGFTEV 

       430        440        450        460        470        480 
LYKVATRPEK RIGSDEVWDT AEAALMESLR RTGCEFEVSP GEGAFYGPKV EYTLKDAIGR 

       490        500        510        520        530        540 
HWQCGTIQVD FSMPVRLGAE YVDQNDQRRP PVMLHRAILG SLERFIGMLI ENHAGAMPPW 

       550        560        570        580        590        600 
LAPVQAVVCC ISEPSADYAA EITQSLKKQG FRVESDLRGE KITRKIREHS LQKVPYILVV 

       610        620        630        640        650 
GDKEKQNGTV AVRGLGGLDL GAIAYDEFVA RLSEDVSTRR DVNQPGSSAA 

« Hide

References

[1]"Complete genome sequence of the haloaromatic acid-degrading bacterium Achromobacter xylosoxidans A8."
Strnad H., Ridl J., Paces J., Kolar M., Vlcek C., Paces V.
J. Bacteriol. 193:791-792(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A8 EMBL ADP15584.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002287 Genomic DNA. Translation: ADP15584.1.
RefSeqYP_003978299.1. NC_014640.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP15584; ADP15584; AXYL_02262.
GeneID9896594.
KEGGaxy:AXYL_02262.
PATRIC42557550. VBIAchXyl160325_2255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000003880.
KOK01868.
OMAHFKLQKI.

Enzyme and pathway databases

BioCycAXYL762376:GJUB-2262-MONOMER.

Family and domain databases

Gene3D3.10.20.30. 1 hit.
3.40.50.800. 1 hit.
HAMAPMF_00184. Thr_tRNA_synth.
InterProIPR002314. aa-tRNA-synt_IIb_cons-dom.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR012675. Beta-grasp_dom.
IPR004095. TGS.
IPR012676. TGS-like.
IPR002320. Thr-tRNA-ligase_IIa.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
IPR012947. tRNA_SAD.
[Graphical view]
PfamPF03129. HGTP_anticodon. 1 hit.
PF02824. TGS. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view]
PRINTSPR01047. TRNASYNTHTHR.
SMARTSM00863. tRNA_SAD. 1 hit.
[Graphical view]
SUPFAMSSF52954. SSF52954. 1 hit.
SSF55186. SSF55186. 1 hit.
SSF81271. SSF81271. 1 hit.
TIGRFAMsTIGR00418. thrS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3HJW2_ACHXA
AccessionPrimary (citable) accession number: E3HJW2
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: July 9, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)