Skip Header

Contribute Send feedback
Read comments (?) or add your own

E3HDJ1 (E3HDJ1_ILYPC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Tryptophan synthase alpha chain HAMAP-Rule MF_00131 RuleBase RU000601
EC=4.2.1.20 HAMAP-Rule MF_00131 RuleBase RU000601
Gene names
Name:trpA HAMAP-Rule MF_00131
Ordered Locus Names:Ilyop_2418 EMBL ADO84177.1
Encoded onPlasmid pILYOP01 EMBL ADO84177.1
OrganismIlyobacter polytropus (strain DSM 2926 / CuHBu1) [Complete proteome] [HAMAP] EMBL ADO84177.1
Taxonomic identifier572544 [NCBI]
Taxonomic lineageBacteria › Fusobacteria › Fusobacteriales › Fusobacteriaceae › Ilyobacter ›

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate By similarity. HAMAP-Rule MF_00131 SAAS SAAS002028 RuleBase RU000601

Catalytic activity

L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. HAMAP-Rule MF_00131 SAAS SAAS002028 RuleBase RU000601

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5. HAMAP-Rule MF_00131 SAAS SAAS002028 RuleBase RU000601

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP-Rule MF_00131 SAAS SAAS002028 RuleBase RU000601

Sequence similarities

Belongs to the TrpA family. HAMAP-Rule MF_00131 RuleBase RU003662

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site451Proton acceptor By similarity HAMAP-Rule MF_00131
Active site561Proton acceptor By similarity HAMAP-Rule MF_00131

Sequences

Sequence LengthMass (Da)Tools
E3HDJ1 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 1CCFC49E2111BF7E

FASTA25027,006
        10         20         30         40         50         60 
MGRIENALKK GEKNLIAYLT AGDPCIEKTP ELVLGMESGG AALVEIGIPY SDPLADGPVI 

        70         80         90        100        110        120 
QAASTRALSK DISIEKIFDA VEKIRKESQI PLVFLVYYNT IHNYGGEEFL KKCEETGVDG 

       130        140        150        160        170        180 
LIIPDLPMEE QKELPKNAAV SIIPLVALNS GDRIENIVKD ATGFVYCISS FGVTGTRDTI 

       190        200        210        220        230        240 
SNKASEIVSE IKKYTDIPVA LGFGISHNKM VEDVNRYADA AIVGSAIVKV IEKTKGSAKE 

       250 
VEDFVASLLR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002282 Genomic DNA. Translation: ADO84177.1.
RefSeqYP_003968525.1. NC_014633.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO84177; ADO84177; Ilyop_2418.
GeneID9869990.
KEGGipo:Ilyop_2418.
PATRIC42648763. VBIIlyPol34265_2504.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000223816.
KOK01695.

Enzyme and pathway databases

BioCycIPOL572544:GJ9I-2507-MONOMER.
UniPathwayUPA00035; UER00044.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00131. Trp_synth_alpha.
InterProIPR013785. Aldolase_TIM.
IPR011060. RibuloseP-bd_barrel.
IPR018204. Trp_synthase_alpha_AS.
IPR002028. Trp_synthase_suA.
[Graphical view]
PfamPF00290. Trp_syntA. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
TIGRFAMsTIGR00262. trpA. 1 hit.
PROSITEPS00167. TRP_SYNTHASE_ALPHA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3HDJ1_ILYPC
AccessionPrimary (citable) accession number: E3HDJ1
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info