ID   E3HC96_ILYPC            Unreviewed;       447 AA.
AC   E3HC96;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=4-aminobutyrate aminotransferase apoenzyme {ECO:0000313|EMBL:ADO84356.1};
DE            EC=2.6.1.19 {ECO:0000313|EMBL:ADO84356.1};
DE            EC=2.6.1.22 {ECO:0000313|EMBL:ADO84356.1};
GN   OrderedLocusNames=Ilyop_2599 {ECO:0000313|EMBL:ADO84356.1};
OS   Ilyobacter polytropus (strain ATCC 51220 / DSM 2926 / LMG 16218 / CuHBu1).
OG   Plasmid pILYOP01 {ECO:0000313|EMBL:ADO84356.1,
OG   ECO:0000313|Proteomes:UP000006875}.
OC   Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC   Ilyobacter.
OX   NCBI_TaxID=572544 {ECO:0000313|EMBL:ADO84356.1, ECO:0000313|Proteomes:UP000006875};
RN   [1] {ECO:0000313|EMBL:ADO84356.1, ECO:0000313|Proteomes:UP000006875}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51220 / DSM 2926 / LMG 16218 / CuHBu1
RC   {ECO:0000313|Proteomes:UP000006875};
RC   PLASMID=pILYOP01 {ECO:0000313|Proteomes:UP000006875};
RX   PubMed=21304735; DOI=10.4056/sigs.1273360;
RA   Sikorski J., Chertkov O., Lapidus A., Nolan M., Lucas S., Del Rio T.G.,
RA   Tice H., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.D., Brambilla E., Yasawong M.,
RA   Rohde M., Pukall R., Spring S., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Ilyobacter polytropus type strain (CuHbu1).";
RL   Stand. Genomic Sci. 3:304-314(2010).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00008954,
CC       ECO:0000256|RuleBase:RU003560}.
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DR   EMBL; CP002282; ADO84356.1; -; Genomic_DNA.
DR   RefSeq; WP_013389014.1; NC_014633.1.
DR   AlphaFoldDB; E3HC96; -.
DR   KEGG; ipo:Ilyop_2599; -.
DR   HOGENOM; CLU_016922_10_0_0; -.
DR   OrthoDB; 9801052at2; -.
DR   Proteomes; UP000006875; Plasmid pILYOP01.
DR   GO; GO:0047298; F:(S)-3-amino-2-methylpropionate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034386; F:4-aminobutyrate:2-oxoglutarate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004632; 4NH2But_aminotransferase_bac.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR049704; Aminotrans_3_PPA_site.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR00700; GABAtrnsam; 1.
DR   PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR   PANTHER; PTHR11986:SF58; LEUCINE_METHIONINE RACEMASE; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:ADO84356.1};
KW   Plasmid {ECO:0000313|EMBL:ADO84356.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|RuleBase:RU003560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006875};
KW   Transferase {ECO:0000313|EMBL:ADO84356.1}.
SQ   SEQUENCE   447 AA;  48954 MW;  1A81CC44CB6A5F4E CRC64;
     MILEKNAKIT TAIPGPKSKE LLEKRLKYVA RGVSYSTEVF VDEAKGALIK DIDGNVFVDF
     AAGIGVQNVG HCDEEIVETI KSQVEKNIHT SFNVAMYEPY INLAEKLVAA TPGDYDKKAL
     LINSGTEAVE NAVKIARKYT GKPMILSLEN AFHGRTYMSM TLTSKVKPYK YGFAPYNSDT
     HKIPSPYCYR CQFGKKHPGC NLECAQKLED LLKGELSADM IAALVVEPVQ GEGGFIVPPK
     GYLQRLQKIC NDNNILFIVD EIQAGFARTG TLFASEQFDI EPDMMTMSKS LAAGMPLAAV
     VGKEEIMENP IVGSIGGTFS GNPVACAAAI KVLEKIEKEK LTERANAIGE KIKSRLSEMQ
     KKYPVIGDIR GLGAMCAVEF ITDPESKEPN KEIIGKITKE SLQEGVIFIS AGIYGNVLRF
     LPPLVMTDEQ LEYGLDVLEK SLEKALS
//