Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alanine racemase

Gene

Ilyop_0365

Organism
Ilyobacter polytropus (strain DSM 2926 / CuHBu1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei33 – 331Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei127 – 1271SubstrateUniRule annotation
Active sitei252 – 2521Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei300 – 3001Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciIPOL572544:GJ9I-382-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Ilyop_0365Imported
OrganismiIlyobacter polytropus (strain DSM 2926 / CuHBu1)Imported
Taxonomic identifieri572544 [NCBI]
Taxonomic lineageiBacteriaFusobacteriaFusobacterialesFusobacteriaceaeIlyobacter
ProteomesiUP000006875 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei33 – 331N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE3HB04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiPSDWVRP.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

E3HB04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAWADINLD NLIYNLNIIK EFAGSKKIMC VIKADGYGMG AVECARILSE
60 70 80 90 100
NGVENFGVAC YEEGYELYKA GIKGEILLLG ATPFENIADA VKCGFQITIS
110 120 130 140 150
SFEQIDFLRR NNLHPEVHIK VDTGMGRLGF SHEEALKAIK IIRDENIADI
160 170 180 190 200
VGVYSHLSVA DMPEKDQFTL DQIEKFKVFE KMESIKYKHI LNSSGLLRFA
210 220 230 240 250
DATESNLVRV GIILHGVVPF ESELQKKFKP VFSFKTKIIF LNKITEKTYV
260 270 280 290 300
SYGNTETAEP GDLIATMAVG YADGFVREFS NGGIVEIDGV GCRVIGKICM
310 320 330 340 350
DMTMIKIPEE LKDKVQVGTE VTIIGKDILK KAECIGTIPY EIMIGLGRRV
360 370
ARFYIKNGKV LKFKSLQESE AKEFQKG
Length:377
Mass (Da):42,102
Last modified:January 10, 2011 - v1
Checksum:iC817048365C72E28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002281 Genomic DNA. Translation: ADO82153.1.
RefSeqiWP_013386823.1. NC_014632.1.
YP_003966501.1. NC_014632.1.

Genome annotation databases

EnsemblBacteriaiADO82153; ADO82153; Ilyop_0365.
KEGGiipo:Ilyop_0365.
PATRICi42644383. VBIIlyPol34265_0378.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002281 Genomic DNA. Translation: ADO82153.1.
RefSeqiWP_013386823.1. NC_014632.1.
YP_003966501.1. NC_014632.1.

3D structure databases

ProteinModelPortaliE3HB04.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO82153; ADO82153; Ilyop_0365.
KEGGiipo:Ilyop_0365.
PATRICi42644383. VBIIlyPol34265_0378.

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiPSDWVRP.

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.
BioCyciIPOL572544:GJ9I-382-MONOMER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 2926 / CuHBu1Imported.

Entry informationi

Entry nameiE3HB04_ILYPC
AccessioniPrimary (citable) accession number: E3HB04
Entry historyi
Integrated into UniProtKB/TrEMBL: January 10, 2011
Last sequence update: January 10, 2011
Last modified: March 31, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.