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E3H8R7 (E3H8R7_ILYPC) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=2.7.1.21 EMBL ADO83331.1
EC=6.3.3.3 EMBL ADO83331.1
Gene names
Ordered Locus Names:Ilyop_1552 EMBL ADO83331.1
OrganismIlyobacter polytropus (strain DSM 2926 / CuHBu1) [Complete proteome] [HAMAP] EMBL ADO83331.1
Taxonomic identifier572544 [NCBI]
Taxonomic lineageBacteriaFusobacteriaFusobacterialesFusobacteriaceaeIlyobacter

Protein attributes

Sequence length410 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472

Catalytic activity

ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472

Cofactor

Magnesium By similarity. SAAS SAAS004472

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472

Subunit structure

Homotetramer By similarity. SAAS SAAS020633

Subcellular location

Cytoplasm By similarity SAAS SAAS004472.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165

Sequences

Sequence LengthMass (Da)Tools
E3H8R7 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: C26462E2FC69FFDF

FASTA41045,957
        10         20         30         40         50         60 
MHFLLTEGMG WIEVITGGMF SGKSEELIRR LIRSKYASQK VVAFKHSIDK RYDESNVVSH 

        70         80         90        100        110        120 
SSIFIEGVPA ASVKEMEKIF YEKYSDAEVI GIDEVQFFGE PVVEFCEKLS DMGKRVIVAG 

       130        140        150        160        170        180 
LDQDFRGEPF EPIDSLLAKA EYVDKLSAIC AVCGNPASRT QRLVNGEPAY YNDPVVLVGA 

       190        200        210        220        230        240 
SESYEARCRK CHVVKREDNK EGKLYFIVGT DTDIGKTYAG LKLVKQEMDK GLKVTAIKPV 

       250        260        270        280        290        300 
ETGSETFPEN LEGSDSYAYA RLLGKNVEDV NIFFYKKPMS PDAAAEADET SVDIKTIKEK 

       310        320        330        340        350        360 
IDKELLENDV VFVEGAGGLL VPFVENYMYL DLLVDYRKKS EVILISGNVL GTINHTLLTI 

       370        380        390        400        410 
DVLKRNDIKI KGVVFNNKEN IEDKKFLKNN VETVKRIGKV EILAENEYGE 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002281 Genomic DNA. Translation: ADO83331.1.
RefSeqYP_003967679.1. NC_014632.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO83331; ADO83331; Ilyop_1552.
GeneID9869065.
KEGGipo:Ilyop_1552.
PATRIC42646847. VBIIlyPol34265_1600.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000109206.
KOK00857.
OMANGEPAYY.

Enzyme and pathway databases

BioCycIPOL572544:GJ9I-1583-MONOMER.
UniPathwayUPA00078; UER00161.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
MF_00336. BioD.
InterProIPR004472. DTB_synth_BioD.
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 2 hits.
TIGRFAMsTIGR00347. bioD. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3H8R7_ILYPC
AccessionPrimary (citable) accession number: E3H8R7
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)