E3H5M4 (E3H5M4_ROTDC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr EMBL ADP39714.1
Ordered Locus Names:	HMPREF0733_10256 EMBL ADP39714.1

Organism

Rothia dentocariosa (strain ATCC 17931 / CDC X599 / XDIA) [Complete proteome] [HAMAP]

Taxonomic identifier

762948 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Rothia › Rothia dentocariosa

Protein attributes

Sequence length	437 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL ADP39714.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E3H5M4 [UniParc]. Last modified January 11, 2011. Version 1. Checksum: EB3E27B86A9A5F81	FASTA	437	46,730
	10 20 30 40 50 60 MTVPTRPLYT PNLQPGEAER TAIIDLNALE HNTRVLKDMI GERKLIAVVK ADAYGHGAYP 70 80 90 100 110 120 VARSVLEAGA DILGVVHVTE ALELRSEGIT APIIAWLHTP QTDFDEALEA DIILGASGWD 130 140 150 160 170 180 LEAIAEAANR TKKRARVHLK VDTGLGRNGS TFEDWPALVA RALELEAAGL VRIEGIFSHL 190 200 210 220 230 240 AVADEPERPE TARQITRLNE FVTVARSAGL TPELVHLANS PGTITGASPL YNTNEAVLAD 250 260 270 280 290 300 AVRCGIALYG LSPLAGVSSK DLNLRPVMTL GTHVCNVKEV PAGQGVSYGL RYSTDKPTTL 310 320 330 340 350 360 ALIPLGYADG VPRIAEGAPV RIYPRADAAN PVEPRTYRVV GRIAMDQLVV DLEEPGLADP 370 380 390 400 410 420 ARGILGGSAV LFGSGDNPPV EEWAAAAQTI NYEIVTRISP RVIRIYRGGA WVEREVDGLH 430 ALGSLFGLDD EQTPETV

References

[1]

"The complete genome of Rothia dentocariosa ATCC 17931." Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A., Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X., Perez L., Shen H., Wang Q., Watt J. , Xi L., Xin Y., Zhou J., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A., Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B., Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R. Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17931 / CDC X599 / XDIA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002280 Genomic DNA. Translation: ADP39714.1.
RefSeq	YP_003983148.1. NC_014643.1.
3D structure databases
ProteinModelPortal	E3H5M4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADP39714; ADP39714; HMPREF0733_10256.
GeneID	9901508.
KEGG	rdn:HMPREF0733_10256.
PATRIC	42675380. VBIRotDen160907_0254.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
OMA	DINIATY.
Enzyme and pathway databases
BioCyc	RDEN762948:GHPW-258-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E3H5M4_ROTDC

Accession

Primary (citable) accession number: E3H5M4

Entry history

Integrated into UniProtKB/TrEMBL:	January 11, 2011
Last sequence update:	January 11, 2011
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)