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E3H5M4 (E3H5M4_ROTDC) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site501Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2881Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1471Substrate By similarity HAMAP-Rule MF_01201
Binding site3451Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue501N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E3H5M4 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: EB3E27B86A9A5F81

FASTA43746,730
        10         20         30         40         50         60 
MTVPTRPLYT PNLQPGEAER TAIIDLNALE HNTRVLKDMI GERKLIAVVK ADAYGHGAYP 

        70         80         90        100        110        120 
VARSVLEAGA DILGVVHVTE ALELRSEGIT APIIAWLHTP QTDFDEALEA DIILGASGWD 

       130        140        150        160        170        180 
LEAIAEAANR TKKRARVHLK VDTGLGRNGS TFEDWPALVA RALELEAAGL VRIEGIFSHL 

       190        200        210        220        230        240 
AVADEPERPE TARQITRLNE FVTVARSAGL TPELVHLANS PGTITGASPL YNTNEAVLAD 

       250        260        270        280        290        300 
AVRCGIALYG LSPLAGVSSK DLNLRPVMTL GTHVCNVKEV PAGQGVSYGL RYSTDKPTTL 

       310        320        330        340        350        360 
ALIPLGYADG VPRIAEGAPV RIYPRADAAN PVEPRTYRVV GRIAMDQLVV DLEEPGLADP 

       370        380        390        400        410        420 
ARGILGGSAV LFGSGDNPPV EEWAAAAQTI NYEIVTRISP RVIRIYRGGA WVEREVDGLH 

       430 
ALGSLFGLDD EQTPETV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002280 Genomic DNA. Translation: ADP39714.1.
RefSeqYP_003983148.1. NC_014643.1.

3D structure databases

ProteinModelPortalE3H5M4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP39714; ADP39714; HMPREF0733_10256.
GeneID9901508.
KEGGrdn:HMPREF0733_10256.
PATRIC42675380. VBIRotDen160907_0254.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMAWELERVA.

Enzyme and pathway databases

BioCycRDEN762948:GHPW-259-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3H5M4_ROTDC
AccessionPrimary (citable) accession number: E3H5M4
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: July 9, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)