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E3GXT0

- E3GXT0_METFV

UniProt

E3GXT0 - E3GXT0_METFV

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciMFER523846:GC24-322-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    Ordered Locus Names:Mfer_0309Imported
    OrganismiMethanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)Imported
    Taxonomic identifieri523846 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanothermaceaeMethanothermus
    ProteomesiUP000002315: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000038601.
    KOiK01595.
    OMAiDEYMPDY.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E3GXT0-1 [UniParc]FASTAAdd to Basket

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    MYIPRCMSTQ HPDNVNPPFF SPNSEIKGED EVTETYYVFS HLGCDEQMWD    50
    CEGKEVDNYV VKKLLTKYEL FFRENKLGKD VFLTLRVPNP AIERAESKIL 100
    IETLESIPRS YDTAKVFYGE DIAPIFEVIL PMTTSANDLN RIYYYYKKFV 150
    AGKEKMLIRK KDITVKEWIG SFKPKEINVI PLFEDYKSML NSDKITENYL 200
    RDKNFEYQRV FLARSDPAMN YGMISALLLN KIALMKLDEL AEKISIDIYP 250
    IIGIGSAPFR GNLKPKTVDQ IIAEYPSVHT FTIQSSFKYD NPPSDVSKAI 300
    KKLKSKKKKN ADIVDIEKSL DIINKYTEQY QKQITNVASI INRLSRFVPS 350
    RRKRKLHIGL FGYSRKMGNI VLPRAITFTC VLYSIGVPPE ILGFDALSEK 400
    DIDFLSDIYV NFEKDFYDAL KYLDWESPLI TDSLKKSVRE HFPEVEEDRK 450
    HVNISRKIYH LLATDGTDSI KESILEAANL RKFLG 485
    Length:485
    Mass (Da):56,175
    Last modified:January 11, 2011 - v1
    Checksum:iA9E6280A83D9BAE0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002278 Genomic DNA. Translation: ADP77112.1.
    RefSeqiYP_004003874.1. NC_014658.1.

    Genome annotation databases

    EnsemblBacteriaiADP77112; ADP77112; Mfer_0309.
    GeneIDi9962024.
    KEGGimfv:Mfer_0309.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002278 Genomic DNA. Translation: ADP77112.1 .
    RefSeqi YP_004003874.1. NC_014658.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADP77112 ; ADP77112 ; Mfer_0309 .
    GeneIDi 9962024.
    KEGGi mfv:Mfer_0309.

    Phylogenomic databases

    HOGENOMi HOG000038601.
    KOi K01595.
    OMAi DEYMPDY.

    Enzyme and pathway databases

    BioCyci MFER523846:GC24-322-MONOMER.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43054 / DSM 2088 / JCM 10308 / V24 SImported.

    Entry informationi

    Entry nameiE3GXT0_METFV
    AccessioniPrimary (citable) accession number: E3GXT0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3