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E3GXT0

- E3GXT0_METFV

UniProt

E3GXT0 - E3GXT0_METFV

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMFER523846:GC24-322-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Mfer_0309Imported
OrganismiMethanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)Imported
Taxonomic identifieri523846 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanothermaceaeMethanothermus
ProteomesiUP000002315: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.
OMAiDEYMPDY.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

E3GXT0 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYIPRCMSTQ HPDNVNPPFF SPNSEIKGED EVTETYYVFS HLGCDEQMWD
60 70 80 90 100
CEGKEVDNYV VKKLLTKYEL FFRENKLGKD VFLTLRVPNP AIERAESKIL
110 120 130 140 150
IETLESIPRS YDTAKVFYGE DIAPIFEVIL PMTTSANDLN RIYYYYKKFV
160 170 180 190 200
AGKEKMLIRK KDITVKEWIG SFKPKEINVI PLFEDYKSML NSDKITENYL
210 220 230 240 250
RDKNFEYQRV FLARSDPAMN YGMISALLLN KIALMKLDEL AEKISIDIYP
260 270 280 290 300
IIGIGSAPFR GNLKPKTVDQ IIAEYPSVHT FTIQSSFKYD NPPSDVSKAI
310 320 330 340 350
KKLKSKKKKN ADIVDIEKSL DIINKYTEQY QKQITNVASI INRLSRFVPS
360 370 380 390 400
RRKRKLHIGL FGYSRKMGNI VLPRAITFTC VLYSIGVPPE ILGFDALSEK
410 420 430 440 450
DIDFLSDIYV NFEKDFYDAL KYLDWESPLI TDSLKKSVRE HFPEVEEDRK
460 470 480
HVNISRKIYH LLATDGTDSI KESILEAANL RKFLG
Length:485
Mass (Da):56,175
Last modified:January 11, 2011 - v1
Checksum:iA9E6280A83D9BAE0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002278 Genomic DNA. Translation: ADP77112.1.
RefSeqiYP_004003874.1. NC_014658.1.

Genome annotation databases

EnsemblBacteriaiADP77112; ADP77112; Mfer_0309.
GeneIDi9962024.
KEGGimfv:Mfer_0309.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002278 Genomic DNA. Translation: ADP77112.1 .
RefSeqi YP_004003874.1. NC_014658.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADP77112 ; ADP77112 ; Mfer_0309 .
GeneIDi 9962024.
KEGGi mfv:Mfer_0309.

Phylogenomic databases

HOGENOMi HOG000038601.
KOi K01595.
OMAi DEYMPDY.

Enzyme and pathway databases

BioCyci MFER523846:GC24-322-MONOMER.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43054 / DSM 2088 / JCM 10308 / V24 SImported.

Entry informationi

Entry nameiE3GXT0_METFV
AccessioniPrimary (citable) accession number: E3GXT0
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: October 1, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3