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E3GWN9 (RIBL_METFV) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:Mfer_1172
OrganismMethanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S) [Complete proteome] [HAMAP]
Taxonomic identifier523846 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanothermaceaeMethanothermus

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 145145FAD synthase HAMAP-Rule MF_02115
PRO_0000406275

Regions

Nucleotide binding5 – 62ATP By similarity
Nucleotide binding10 – 134ATP By similarity
Nucleotide binding90 – 934ATP By similarity

Sites

Binding site1191ATP; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
E3GWN9 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: ACBB1A72DA8AD0F8

FASTA14516,660
        10         20         30         40         50         60 
MATGTFDIIH PGHGFYLKKA KELGGKNSKL VVIVARDSTV RARKRKPVIN EKQRLEVVKM 

        70         80         90        100        110        120 
LKPVDEAYLG CEGDIFKTVE KIKPDIIALG PDQDFDEKEL QKELKKRNID CKVVRIKEYK 

       130        140 
KSPLDSTCKI IKKIKQMKFD DIEKC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002278 Genomic DNA. Translation: ADP77958.1.
RefSeqYP_004004720.1. NC_014658.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP77958; ADP77958; Mfer_1172.
GeneID9962919.
KEGGmfv:Mfer_1172.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000284153.
KOK14656.
OMAIVLGHDQ.

Enzyme and pathway databases

BioCycMFER523846:GC24-1218-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_METFV
AccessionPrimary (citable) accession number: E3GWN9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: January 11, 2011
Last modified: May 14, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways