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E3GV74

- E3GV74_HAEI2

UniProt

E3GV74 - E3GV74_HAEI2

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Haemophilus influenzae (strain R2846 / 12)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei138 – 1381UniRule annotation
    Active sitei545 – 5451UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciHINF262727:GLDQ-1114-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotationImported
    Ordered Locus Names:R2846_1114Imported
    OrganismiHaemophilus influenzae (strain R2846 / 12)Imported
    Taxonomic identifieri262727 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000006874: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.
    OMAiELSTISC.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E3GV74-1 [UniParc]FASTAAdd to Basket

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    MTQEYSTLRN NISMLGRFLG ETINDAQGED ILELIENIRK LSRNSRAGDD    50
    KARQALLDTL GSISNENIIP VARAFSQFLN LTNIAEQYQT ISREHSLAQS 100
    SSQSLSELFK RLKEQNASVE EVHKTVEKLL IELVLTAHPT ETTRRSLIHK 150
    HIEINKCLSK LEHHDLTEKE RNIIERLLLR LIAEAWHTNE IRTVRPTPFD 200
    EAKWGFAMLE NSLWQAVPEF LRQLNETARE FLGYDLPVGL KPVRISSWMG 250
    GDRDGNPFVT AQITKKVLYF ARWKAADLFL QDISKLADEL SMMKCSDEFR 300
    DKYGEHLEPY RFVVKNLRNQ LTATLAYFDD HLSNRTPRVS ESEIILEDNQ 350
    LWEPLYDCYQ SLIQCGMRII ANGSLLNILH RISCFGVTLS QMDIRQESTR 400
    HTDAIAEITR YIGLGDYSQW MEDDKQAFLI RELSSRRPLI PQNWTPSPET 450
    KEILDTCKVI AQQKQGVIAC YVISMARSAS DVLAVHLLLK ESGVPYHIPV 500
    VPLFETLEDL DAAEKVMTQL FNVGWYRGVI NNRQMVMIGY SDSAKDAGMM 550
    AASWAQYRAQ EALVNLTEKL GIELTLFHGR GGTIGRGGAP AHAALLSQPP 600
    RSLKNGLRVT EQGEMIRFKL GLPAVAVETF DLYASAILEA NLLPPPEPKP 650
    EWRTIMDELS TISCDIYRGV VRGDKDFVPY FRSATPEQEL SKLPLGSRPA 700
    KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGAAIRQV IEQGKGDIIH 750
    KMCENWPFFS TRIGMLEMVF SKSDTWLSQQ YDQRLVKKEL WYLGENLRKQ 800
    LEDDIQTVLS LSHQSELMSD LPWIADSIAL RNIYTDPLNL LQVELLHRFR 850
    KNPEQVNPDV EQALMITITG IAAGMRNTG 879
    Length:879
    Mass (Da):100,064
    Last modified:January 11, 2011 - v1
    Checksum:i3EE994BD4F6F2D90
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002276 Genomic DNA. Translation: ADO96508.1.
    RefSeqiYP_005829563.1. NC_017452.1.

    Genome annotation databases

    EnsemblBacteriaiADO96508; ADO96508; R2846_1114.
    GeneIDi12597792.
    KEGGihie:R2846_1114.
    PATRICi43043720. VBIHaeInf30952_1126.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002276 Genomic DNA. Translation: ADO96508.1 .
    RefSeqi YP_005829563.1. NC_017452.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO96508 ; ADO96508 ; R2846_1114 .
    GeneIDi 12597792.
    KEGGi hie:R2846_1114.
    PATRICi 43043720. VBIHaeInf30952_1126.

    Phylogenomic databases

    KOi K01595.
    OMAi ELSTISC.

    Enzyme and pathway databases

    BioCyci HINF262727:GLDQ-1114-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the middle ear isolate Haemophilus influenzae R2846."
      VanWagoner T.M., Erwin A.L., Kaul R., Mahaffey M., Zhou Y., Aggarwal G., Chang J., Deng H., Gillett W., Haugen E., Kibukawa M., Phelps K., Saenphimma C., Sivam D., Worthy E.A., Olson M.V., Stull T.L., Smith A.L.
      Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: R2846 / 12Imported.

    Entry informationi

    Entry nameiE3GV74_HAEI2
    AccessioniPrimary (citable) accession number: E3GV74
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3