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E3GV74 (E3GV74_HAEI2) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595 EMBL ADO96508.1
Ordered Locus Names:R2846_1114 EMBL ADO96508.1
OrganismHaemophilus influenzae (strain R2846 / 12) [Complete proteome] [HAMAP]
Taxonomic identifier262727 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›

Protein attributes

Sequence length879 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595 SAAS SAAS022805

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1381 By similarity HAMAP-Rule MF_00595
Active site5451 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
E3GV74 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 3EE994BD4F6F2D90

FASTA879100,064
        10         20         30         40         50         60 
MTQEYSTLRN NISMLGRFLG ETINDAQGED ILELIENIRK LSRNSRAGDD KARQALLDTL 

        70         80         90        100        110        120 
GSISNENIIP VARAFSQFLN LTNIAEQYQT ISREHSLAQS SSQSLSELFK RLKEQNASVE 

       130        140        150        160        170        180 
EVHKTVEKLL IELVLTAHPT ETTRRSLIHK HIEINKCLSK LEHHDLTEKE RNIIERLLLR 

       190        200        210        220        230        240 
LIAEAWHTNE IRTVRPTPFD EAKWGFAMLE NSLWQAVPEF LRQLNETARE FLGYDLPVGL 

       250        260        270        280        290        300 
KPVRISSWMG GDRDGNPFVT AQITKKVLYF ARWKAADLFL QDISKLADEL SMMKCSDEFR 

       310        320        330        340        350        360 
DKYGEHLEPY RFVVKNLRNQ LTATLAYFDD HLSNRTPRVS ESEIILEDNQ LWEPLYDCYQ 

       370        380        390        400        410        420 
SLIQCGMRII ANGSLLNILH RISCFGVTLS QMDIRQESTR HTDAIAEITR YIGLGDYSQW 

       430        440        450        460        470        480 
MEDDKQAFLI RELSSRRPLI PQNWTPSPET KEILDTCKVI AQQKQGVIAC YVISMARSAS 

       490        500        510        520        530        540 
DVLAVHLLLK ESGVPYHIPV VPLFETLEDL DAAEKVMTQL FNVGWYRGVI NNRQMVMIGY 

       550        560        570        580        590        600 
SDSAKDAGMM AASWAQYRAQ EALVNLTEKL GIELTLFHGR GGTIGRGGAP AHAALLSQPP 

       610        620        630        640        650        660 
RSLKNGLRVT EQGEMIRFKL GLPAVAVETF DLYASAILEA NLLPPPEPKP EWRTIMDELS 

       670        680        690        700        710        720 
TISCDIYRGV VRGDKDFVPY FRSATPEQEL SKLPLGSRPA KRNPNGGVES LRAIPWIFAW 

       730        740        750        760        770        780 
MQNRLMLPAW LGAGAAIRQV IEQGKGDIIH KMCENWPFFS TRIGMLEMVF SKSDTWLSQQ 

       790        800        810        820        830        840 
YDQRLVKKEL WYLGENLRKQ LEDDIQTVLS LSHQSELMSD LPWIADSIAL RNIYTDPLNL 

       850        860        870 
LQVELLHRFR KNPEQVNPDV EQALMITITG IAAGMRNTG

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References

[1]"Genome sequence of the middle ear isolate Haemophilus influenzae R2846."
VanWagoner T.M., Erwin A.L., Kaul R., Mahaffey M., Zhou Y., Aggarwal G., Chang J., Deng H., Gillett W., Haugen E., Kibukawa M., Phelps K., Saenphimma C., Sivam D., Worthy E.A., Olson M.V., Stull T.L., Smith A.L.
Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R2846 / 12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002276 Genomic DNA. Translation: ADO96508.1.
RefSeqYP_005829563.1. NC_017452.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO96508; ADO96508; R2846_1114.
GeneID12597792.
KEGGhie:R2846_1114.
PATRIC43043720. VBIHaeInf30952_1126.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.
OMAAIPWVFG.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3GV74_HAEI2
AccessionPrimary (citable) accession number: E3GV74
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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