SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E3GV74

- E3GV74_HAEI2

UniProt

E3GV74 - E3GV74_HAEI2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, R2846_1114
Organism
Haemophilus influenzae (strain R2846 / 12)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei545 – 5451 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciHINF262727:GLDQ-1114-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:R2846_1114Imported
OrganismiHaemophilus influenzae (strain R2846 / 12)Imported
Taxonomic identifieri262727 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000006874: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiELSTISC.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3GV74-1 [UniParc]FASTAAdd to Basket

« Hide

MTQEYSTLRN NISMLGRFLG ETINDAQGED ILELIENIRK LSRNSRAGDD    50
KARQALLDTL GSISNENIIP VARAFSQFLN LTNIAEQYQT ISREHSLAQS 100
SSQSLSELFK RLKEQNASVE EVHKTVEKLL IELVLTAHPT ETTRRSLIHK 150
HIEINKCLSK LEHHDLTEKE RNIIERLLLR LIAEAWHTNE IRTVRPTPFD 200
EAKWGFAMLE NSLWQAVPEF LRQLNETARE FLGYDLPVGL KPVRISSWMG 250
GDRDGNPFVT AQITKKVLYF ARWKAADLFL QDISKLADEL SMMKCSDEFR 300
DKYGEHLEPY RFVVKNLRNQ LTATLAYFDD HLSNRTPRVS ESEIILEDNQ 350
LWEPLYDCYQ SLIQCGMRII ANGSLLNILH RISCFGVTLS QMDIRQESTR 400
HTDAIAEITR YIGLGDYSQW MEDDKQAFLI RELSSRRPLI PQNWTPSPET 450
KEILDTCKVI AQQKQGVIAC YVISMARSAS DVLAVHLLLK ESGVPYHIPV 500
VPLFETLEDL DAAEKVMTQL FNVGWYRGVI NNRQMVMIGY SDSAKDAGMM 550
AASWAQYRAQ EALVNLTEKL GIELTLFHGR GGTIGRGGAP AHAALLSQPP 600
RSLKNGLRVT EQGEMIRFKL GLPAVAVETF DLYASAILEA NLLPPPEPKP 650
EWRTIMDELS TISCDIYRGV VRGDKDFVPY FRSATPEQEL SKLPLGSRPA 700
KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGAAIRQV IEQGKGDIIH 750
KMCENWPFFS TRIGMLEMVF SKSDTWLSQQ YDQRLVKKEL WYLGENLRKQ 800
LEDDIQTVLS LSHQSELMSD LPWIADSIAL RNIYTDPLNL LQVELLHRFR 850
KNPEQVNPDV EQALMITITG IAAGMRNTG 879
Length:879
Mass (Da):100,064
Last modified:January 11, 2011 - v1
Checksum:i3EE994BD4F6F2D90
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002276 Genomic DNA. Translation: ADO96508.1.
RefSeqiYP_005829563.1. NC_017452.1.

Genome annotation databases

EnsemblBacteriaiADO96508; ADO96508; R2846_1114.
GeneIDi12597792.
KEGGihie:R2846_1114.
PATRICi43043720. VBIHaeInf30952_1126.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002276 Genomic DNA. Translation: ADO96508.1 .
RefSeqi YP_005829563.1. NC_017452.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADO96508 ; ADO96508 ; R2846_1114 .
GeneIDi 12597792.
KEGGi hie:R2846_1114.
PATRICi 43043720. VBIHaeInf30952_1126.

Phylogenomic databases

KOi K01595.
OMAi ELSTISC.

Enzyme and pathway databases

BioCyci HINF262727:GLDQ-1114-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the middle ear isolate Haemophilus influenzae R2846."
    VanWagoner T.M., Erwin A.L., Kaul R., Mahaffey M., Zhou Y., Aggarwal G., Chang J., Deng H., Gillett W., Haugen E., Kibukawa M., Phelps K., Saenphimma C., Sivam D., Worthy E.A., Olson M.V., Stull T.L., Smith A.L.
    Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R2846 / 12.

Entry informationi

Entry nameiE3GV74_HAEI2
AccessioniPrimary (citable) accession number: E3GV74
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: June 11, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi