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Protein

Glutamate decarboxylase

Gene

ELI_0972

Organism
Eubacterium limosum (strain KIST612)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciELIM903814:G1GNM-862-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:ELI_0972Imported
OrganismiEubacterium limosum (strain KIST612)Imported
Taxonomic identifieri903814 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesEubacteriaceaeEubacterium
Proteomesi
  • UP000006873 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei280N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi903814.ELI_0972

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

E3GJR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYSKDDQDK LKDRYLTPIF GTEASDEPLP KYKLRKDPVE PEVAYRLIKD
60 70 80 90 100
DLLDEGSARL NLSTFCQTYM EPEATKIMAE TLEKNAIDKS EYPQTTELEN
110 120 130 140 150
RCVNMIADLW HAPDDEKFLG TSTVGSSEAC MLGGMAMKFR WRNNAIKQGL
160 170 180 190 200
DVKAKKPNLV ISSGYQVCWE KFCVYWDIEM RLVPLDEQHM SMNMDTVMDF
210 220 230 240 250
VDEYTIGIVG IMGITYTGKF DDIKALDTLV EDYNQKNPKF PIYIHVDGAS
260 270 280 290 300
GGMFAPFIEP DLEWDFRLKN VVSINTSGHK YGLVYPGIGW VLWRDEKWLP
310 320 330 340 350
KELIFSVSYL GGSLPTMAIN FSRSASQIIG QYYNFLRYGY EGYKKIHERT
360 370 380 390 400
RDVAMYISKE LEKTGLFEIY NDGSNLPIVC WKMKKDANKE WNLYDLADRI
410 420 430 440 450
RMKGWQVPAY PLPENLQDDI IQRVVVRADL SEQLGVLLME DMNRAIKELD
460 470
EAHILPHGGD QVNNKGVYGF TH
Length:472
Mass (Da):54,332
Last modified:January 11, 2011 - v1
Checksum:i9A32576151576E1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002273 Genomic DNA Translation: ADO35975.1
RefSeqiWP_013379297.1, NC_014624.2

Genome annotation databases

EnsemblBacteriaiADO35975; ADO35975; ELI_0972
KEGGielm:ELI_0972

Similar proteinsi

Entry informationi

Entry nameiE3GJR7_EUBLK
AccessioniPrimary (citable) accession number: E3GJR7
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: April 25, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health