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Protein

Multidrug resistance protein MdtG

Gene

mdtG

Organism
Enterobacter lignolyticus (strain SCF1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciELIG701347:G1GOB-2802-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Multidrug resistance protein MdtGUniRule annotation
Gene namesi
Name:mdtGUniRule annotation
Ordered Locus Names:Entcl_2736
OrganismiEnterobacter lignolyticus (strain SCF1)
Taxonomic identifieri701347 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaePluralibacter
Proteomesi
  • UP000006872 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalUniRule annotationAdd BLAST21
Transmembranei56 – 76HelicalUniRule annotationAdd BLAST21
Transmembranei90 – 110HelicalUniRule annotationAdd BLAST21
Transmembranei113 – 133HelicalUniRule annotationAdd BLAST21
Transmembranei144 – 164HelicalUniRule annotationAdd BLAST21
Transmembranei171 – 191HelicalUniRule annotationAdd BLAST21
Transmembranei222 – 242HelicalUniRule annotationAdd BLAST21
Transmembranei251 – 271HelicalUniRule annotationAdd BLAST21
Transmembranei288 – 308HelicalUniRule annotationAdd BLAST21
Transmembranei317 – 337HelicalUniRule annotationAdd BLAST21
Transmembranei376 – 396HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004145781 – 418Multidrug resistance protein MdtGAdd BLAST418

Proteomic databases

PRIDEiE3GC98

Interactioni

Protein-protein interaction databases

STRINGi701347.Entcl_2736

Structurei

3D structure databases

ProteinModelPortaliE3GC98
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C6X Bacteria
ENOG410ZVCH LUCA
HOGENOMiHOG000066093
KOiK08161
OMAiVIRHNVP
OrthoDBiPOG091H029Y

Family and domain databases

CDDicd06174 MFS, 1 hit
HAMAPiMF_01528 MFS_MdtG, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR023692 Mutidrug-R_MdtG
IPR001958 Tet-R_TetA/multi-R_MdtG
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
PRINTSiPR01035 TCRTETA
SUPFAMiSSF103473 SSF103473, 2 hits
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

E3GC98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSSDAPINW KRNLTITWIG CFLTGAAFSL VMPFLPLYVE SLGVTGHSAL
60 70 80 90 100
NMWSGLVFSI TFLFSAIASP FWGGLADRKG RKIMLLRSAL GMAIVMLLMG
110 120 130 140 150
LAQNIWQFLI LRALLGLLGG FIPNANALIA TQIPRHKSGW ALGTLSTGGV
160 170 180 190 200
SGALLGPLVG GVLADSYGLR PVFFMTASVL FLCFLLTLLF IREQFQPVAK
210 220 230 240 250
KEMLHAREVI ASLKSPKLVL SLFVTTLIIQ VATGSIAPIL TLYVRDLAGN
260 270 280 290 300
VANIAFISGM IASVPGVAAL ISAPRLGKLG DRIGPEKILI AALVISVLLL
310 320 330 340 350
IPMSFVQTPW QLGLLRFLLG AADGALLPAV QTLLVYNATN QIAGRVFSYN
360 370 380 390 400
QSFRDIGNVT GPLIGASVSA NYGFRAVFLV TAMVVLFNAV YTGLSLRRTG
410
ATALPAQDVE KDDTSLVR
Length:418
Mass (Da):44,640
Last modified:January 11, 2011 - v1
Checksum:iE0C3B3A8CC35C7E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002272 Genomic DNA Translation: ADO48984.1
RefSeqiWP_013366717.1, NC_014618.1

Genome annotation databases

EnsemblBacteriaiADO48984; ADO48984; Entcl_2736
KEGGiesc:Entcl_2736

Similar proteinsi

Entry informationi

Entry nameiMDTG_ENTLS
AccessioniPrimary (citable) accession number: E3GC98
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: January 11, 2011
Last modified: May 23, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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