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Protein

Multidrug resistance protein MdtG

Gene

mdtG

Organism
Enterobacter lignolyticus (strain SCF1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciECLO701347:GH9V-2785-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Multidrug resistance protein MdtGUniRule annotation
Gene namesi
Name:mdtGUniRule annotation
Ordered Locus Names:Entcl_2736
OrganismiEnterobacter lignolyticus (strain SCF1)
Taxonomic identifieri701347 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
Proteomesi
  • UP000006872 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3921HelicalUniRule annotationAdd
BLAST
Transmembranei56 – 7621HelicalUniRule annotationAdd
BLAST
Transmembranei90 – 11021HelicalUniRule annotationAdd
BLAST
Transmembranei113 – 13321HelicalUniRule annotationAdd
BLAST
Transmembranei144 – 16421HelicalUniRule annotationAdd
BLAST
Transmembranei171 – 19121HelicalUniRule annotationAdd
BLAST
Transmembranei222 – 24221HelicalUniRule annotationAdd
BLAST
Transmembranei251 – 27121HelicalUniRule annotationAdd
BLAST
Transmembranei288 – 30821HelicalUniRule annotationAdd
BLAST
Transmembranei317 – 33721HelicalUniRule annotationAdd
BLAST
Transmembranei376 – 39621HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 418418Multidrug resistance protein MdtGPRO_0000414578Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi701347.Entcl_2736.

Structurei

3D structure databases

ProteinModelPortaliE3GC98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFTQSNAD.
OrthoDBiPOG091H029Y.

Family and domain databases

CDDicd06174. MFS. 1 hit.
HAMAPiMF_01528. MFS_MdtG. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3GC98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSSDAPINW KRNLTITWIG CFLTGAAFSL VMPFLPLYVE SLGVTGHSAL
60 70 80 90 100
NMWSGLVFSI TFLFSAIASP FWGGLADRKG RKIMLLRSAL GMAIVMLLMG
110 120 130 140 150
LAQNIWQFLI LRALLGLLGG FIPNANALIA TQIPRHKSGW ALGTLSTGGV
160 170 180 190 200
SGALLGPLVG GVLADSYGLR PVFFMTASVL FLCFLLTLLF IREQFQPVAK
210 220 230 240 250
KEMLHAREVI ASLKSPKLVL SLFVTTLIIQ VATGSIAPIL TLYVRDLAGN
260 270 280 290 300
VANIAFISGM IASVPGVAAL ISAPRLGKLG DRIGPEKILI AALVISVLLL
310 320 330 340 350
IPMSFVQTPW QLGLLRFLLG AADGALLPAV QTLLVYNATN QIAGRVFSYN
360 370 380 390 400
QSFRDIGNVT GPLIGASVSA NYGFRAVFLV TAMVVLFNAV YTGLSLRRTG
410
ATALPAQDVE KDDTSLVR
Length:418
Mass (Da):44,640
Last modified:January 11, 2011 - v1
Checksum:iE0C3B3A8CC35C7E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002272 Genomic DNA. Translation: ADO48984.1.
RefSeqiWP_013366717.1. NC_014618.1.

Genome annotation databases

EnsemblBacteriaiADO48984; ADO48984; Entcl_2736.
GeneIDi24908190.
KEGGiesc:Entcl_2736.
PATRICi42599625. VBIEntClo171306_2779.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002272 Genomic DNA. Translation: ADO48984.1.
RefSeqiWP_013366717.1. NC_014618.1.

3D structure databases

ProteinModelPortaliE3GC98.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi701347.Entcl_2736.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO48984; ADO48984; Entcl_2736.
GeneIDi24908190.
KEGGiesc:Entcl_2736.
PATRICi42599625. VBIEntClo171306_2779.

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFTQSNAD.
OrthoDBiPOG091H029Y.

Enzyme and pathway databases

BioCyciECLO701347:GH9V-2785-MONOMER.

Family and domain databases

CDDicd06174. MFS. 1 hit.
HAMAPiMF_01528. MFS_MdtG. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMDTG_ENTLS
AccessioniPrimary (citable) accession number: E3GC98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: January 11, 2011
Last modified: September 7, 2016
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.