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E3GBE3 (E3GBE3_ENTLS) Unreviewed, UniProtKB/TrEMBL

Last modified December 11, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Entcl_2658 EMBL ADO48906.1
OrganismEnterobacter lignolyticus (strain SCF1) [Complete proteome] [HAMAP] EMBL ADO48906.1
Taxonomic identifier701347 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
E3GBE3 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 532FBD2754CBD125

FASTA41645,842
        10         20         30         40         50         60 
MESKVVVPAE GQKITLQNGK LNVPHNPIIP FIEGDGIGVD VTPPMIKVVN AAVEKAYKGE 

        70         80         90        100        110        120 
RKISWMEIYT GEKSTHVYGQ DVWLPAETLD LIREYRVAIK GPLTTPVGGG IRSLNVALRQ 

       130        140        150        160        170        180 
ELDLYVCLRP VRYYQGTPSP VKHPELTDMV IFRENAEDIY AGIEWKADSA DAEKVIKFLR 

       190        200        210        220        230        240 
EEMGVKKIRF PEHCGIGIKP CSEEGTKRLV RAAIEYAIAN DRDSVTLVHK GNIMKFTEGA 

       250        260        270        280        290        300 
FKDWGYQLAR EEFGGELIDG GPWQKIKNPR TGKEIIIKDV IADAFLQQIL LRPAEYDVIA 

       310        320        330        340        350        360 
CMNLNGDYIS DALAAQVGGI GIAPGANIGD ECALFEATHG TAPKYAGQDK VNPGSVILSA 

       370        380        390        400        410 
EMMLRHMEWF EAADLIVKGM EGAIAAKTVT YDFERLMDGA KLLKCSEFGD AIIANM 

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References

[1]"Complete sequence of Enterobacter cloacae SCF1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N. expand/collapse author list , DeAngelis K., Arkin A.P., Chivian D., Edwards B., Woo H., Hazen T.C., Woyke T.
Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SCF1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002272 Genomic DNA. Translation: ADO48906.1.
RefSeqYP_003942190.1. NC_014618.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO48906; ADO48906; Entcl_2658.
GeneID9907711.
KEGGesc:Entcl_2658.
PATRIC42599467. VBIEntClo171306_2700.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.

Enzyme and pathway databases

BioCycECLO701347:GH9V-2707-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3GBE3_ENTLS
AccessionPrimary (citable) accession number: E3GBE3
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: December 11, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)