SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E3G4E2

- E3G4E2_ENTLS

UniProt

E3G4E2 - E3G4E2_ENTLS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Alanine racemase
Gene
Entcl_2000
Organism
Enterobacter lignolyticus (strain SCF1)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei130 – 1301Substrate By similarityUniRule annotation
Active sitei253 – 2531Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei301 – 3011Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciECLO701347:GH9V-2044-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Entcl_2000Imported
OrganismiEnterobacter lignolyticus (strain SCF1)Imported
Taxonomic identifieri701347 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
ProteomesiUP000006872: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE3G4E2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3G4E2-1 [UniParc]FASTAAdd to Basket

« Hide

MSRPVVASLD LQALRHNLSV VRRAAPGSRV WSVVKANAYG HGIDRIWSAL    50
KETDGFAMLN LEEAILLRER GWKGPVLMLE GFFQAEDLAL FDKYRLTTTV 100
HSNWQIKALQ NARLHAPLDV YVKVNSGMNR LGFTPQRLHT AWQQLRALPN 150
VGDMTLMSHF ADAEKPDGIR EAMVQIEQAA EGLGCPRSLS NSAATLWHPE 200
AHFDWVRPGI VLYGASPSGQ WQDIANSGLK PVMTLSSEII GIQNLKPGDT 250
VGYGRLYRAT QEQRIGIVAC GYADGYPRIA PDNTPVLVDG VRTGTVGRVS 300
MDMLAVDLTP CPQAGIGTPV ELWGNEIKID DVASCCGTVG YELMCALAPR 350
VPVVTV 356
Length:356
Mass (Da):38,881
Last modified:January 11, 2011 - v1
Checksum:i81EA89A38F87FE89
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002272 Genomic DNA. Translation: ADO48255.1.
RefSeqiYP_003941539.1. NC_014618.1.

Genome annotation databases

EnsemblBacteriaiADO48255; ADO48255; Entcl_2000.
GeneIDi9907048.
KEGGiesc:Entcl_2000.
PATRICi42598113. VBIEntClo171306_2027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002272 Genomic DNA. Translation: ADO48255.1 .
RefSeqi YP_003941539.1. NC_014618.1.

3D structure databases

ProteinModelPortali E3G4E2.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADO48255 ; ADO48255 ; Entcl_2000 .
GeneIDi 9907048.
KEGGi esc:Entcl_2000.
PATRICi 42598113. VBIEntClo171306_2027.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci ECLO701347:GH9V-2044-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCF1.

Entry informationi

Entry nameiE3G4E2_ENTLS
AccessioniPrimary (citable) accession number: E3G4E2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: July 9, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi