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E3G4E2 (E3G4E2_ENTLS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2531Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3011Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E3G4E2 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 81EA89A38F87FE89

FASTA35638,881
        10         20         30         40         50         60 
MSRPVVASLD LQALRHNLSV VRRAAPGSRV WSVVKANAYG HGIDRIWSAL KETDGFAMLN 

        70         80         90        100        110        120 
LEEAILLRER GWKGPVLMLE GFFQAEDLAL FDKYRLTTTV HSNWQIKALQ NARLHAPLDV 

       130        140        150        160        170        180 
YVKVNSGMNR LGFTPQRLHT AWQQLRALPN VGDMTLMSHF ADAEKPDGIR EAMVQIEQAA 

       190        200        210        220        230        240 
EGLGCPRSLS NSAATLWHPE AHFDWVRPGI VLYGASPSGQ WQDIANSGLK PVMTLSSEII 

       250        260        270        280        290        300 
GIQNLKPGDT VGYGRLYRAT QEQRIGIVAC GYADGYPRIA PDNTPVLVDG VRTGTVGRVS 

       310        320        330        340        350 
MDMLAVDLTP CPQAGIGTPV ELWGNEIKID DVASCCGTVG YELMCALAPR VPVVTV 

« Hide

References

[1]"Complete sequence of Enterobacter cloacae SCF1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N. expand/collapse author list , DeAngelis K., Arkin A.P., Chivian D., Edwards B., Woo H., Hazen T.C., Woyke T.
Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SCF1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002272 Genomic DNA. Translation: ADO48255.1.
RefSeqYP_003941539.1. NC_014618.1.

3D structure databases

ProteinModelPortalE3G4E2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO48255; ADO48255; Entcl_2000.
GeneID9907048.
KEGGesc:Entcl_2000.
PATRIC42598113. VBIEntClo171306_2027.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031446.
KOK01775.
OMAMAHFADA.

Enzyme and pathway databases

BioCycECLO701347:GH9V-2044-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3G4E2_ENTLS
AccessionPrimary (citable) accession number: E3G4E2
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: February 19, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)