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Protein

Ribose 1,5-bisphosphate phosphokinase PhnN

Gene

phnN

Organism
Enterobacter lignolyticus (strain SCF1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).UniRule annotation

Catalytic activityi

ATP + alpha-D-ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Phosphopentomutase (deoB)
  2. no protein annotated in this organism
  3. Ribose 1,5-bisphosphate phosphokinase PhnN (phnN)
This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 178ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECLO701347:GH9V-4156-MONOMER.
UniPathwayiUPA00087; UER00175.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose 1,5-bisphosphate phosphokinase PhnNUniRule annotation (EC:2.7.4.23UniRule annotation)
Alternative name(s):
Ribose 1,5-bisphosphokinaseUniRule annotation
Gene namesi
Name:phnNUniRule annotation
Ordered Locus Names:Entcl_4075
OrganismiEnterobacter lignolyticus (strain SCF1)
Taxonomic identifieri701347 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
Proteomesi
  • UP000006872 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 189189Ribose 1,5-bisphosphate phosphokinase PhnNPRO_0000412782Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi701347.Entcl_4075.

Structurei

3D structure databases

ProteinModelPortaliE3G1M3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribose 1,5-bisphosphokinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105MFQ. Bacteria.
COG3709. LUCA.
HOGENOMiHOG000037637.
KOiK05774.
OMAiMARLIWL.

Family and domain databases

Gene3Di3.40.50.300. 4 hits.
HAMAPiMF_00836. PhnN.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR027417. P-loop_NTPase.
IPR012699. PhnN.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02322. phosphon_PhnN. 1 hit.

Sequencei

Sequence statusi: Complete.

E3G1M3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGKLIWLVG PSGSGKDSLL EALRKQEHPQ MLVAHRYITR PAGAGCENHV
60 70 80 90 100
ALSEHEFFTR AAQHLFALSW HANNLYYGVG MEIDLWLHAG LDVVVNGSRA
110 120 130 140 150
HLPQAKARYG ESLLPVCLQV SPDILRQRLE QRGRENALEI AQRLERAARY
160 170 180
TPQQCVMLNN DGSLLQSVEM FLHLIRTHGN HKESQHACL
Length:189
Mass (Da):21,273
Last modified:January 11, 2011 - v1
Checksum:iE6AA6879E6244D85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002272 Genomic DNA. Translation: ADO50308.1.
RefSeqiWP_013368024.1. NC_014618.1.

Genome annotation databases

EnsemblBacteriaiADO50308; ADO50308; Entcl_4075.
GeneIDi24908769.
KEGGiesc:Entcl_4075.
PATRICi42602409. VBIEntClo171306_4150.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002272 Genomic DNA. Translation: ADO50308.1.
RefSeqiWP_013368024.1. NC_014618.1.

3D structure databases

ProteinModelPortaliE3G1M3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi701347.Entcl_4075.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO50308; ADO50308; Entcl_4075.
GeneIDi24908769.
KEGGiesc:Entcl_4075.
PATRICi42602409. VBIEntClo171306_4150.

Phylogenomic databases

eggNOGiENOG4105MFQ. Bacteria.
COG3709. LUCA.
HOGENOMiHOG000037637.
KOiK05774.
OMAiMARLIWL.

Enzyme and pathway databases

UniPathwayiUPA00087; UER00175.
BioCyciECLO701347:GH9V-4156-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 4 hits.
HAMAPiMF_00836. PhnN.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR027417. P-loop_NTPase.
IPR012699. PhnN.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02322. phosphon_PhnN. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCF1.

Entry informationi

Entry nameiPHNN_ENTLS
AccessioniPrimary (citable) accession number: E3G1M3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: January 11, 2011
Last modified: May 11, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.