Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Corynebacterium pseudotuberculosis (strain I19)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei154 – 1541UniRule annotation
Active sitei598 – 5981UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCPSE889513:GLBZ-1160-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:CpI19_1109Imported
OrganismiCorynebacterium pseudotuberculosis (strain I19)Imported
Taxonomic identifieri889513 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000008202: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3FBC0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRSLSFMSVK ATSAGPLSEQ LVEDIRFLGA LLGEVIKEQE GIAAFDRVEA
60 70 80 90 100
ARQLAFKISR KESQVEDLVA LLKDISAADA IPIIRAFSHF ALLANMVEDL
110 120 130 140 150
HDELGRLQRQ EAGEQDPDST LGATWKKLAN AGITNEKVSS LLSNFQVAPV
160 170 180 190 200
LTAHPTETRR RTIFDAQEHM TTLLKKRHAI LSSETNALTT ARLEENTRHI
210 220 230 240 250
RRWLTLIWQT ALIRVARPRI EDEVEVGLRY YELSLLTAIP EINKQVADHI
260 270 280 290 300
QREYGVNSED ALQSLLIKPG SWIGGDHDGN PYVTAGTLHY ATTRAAETVL
310 320 330 340 350
KFYVRELHQL EHELSLSDRL TDVSPDLRKL ADLGHNDVPS RVDEPYRRAV
360 370 380 390 400
HGVRGRVLAT LASRIGPETV EGSWYSRHAA YTAPEQLAAD LDIIDASLRR
410 420 430 440 450
THDELIADDR LLRIRTAVSS FGFHLYSMDL RQNSESYEDV LTELFERAQV
460 470 480 490 500
TPHYRKLDES EKISVLIAEL SSPRPLIPRD GLPYSELTQR ELDIIFEAKQ
510 520 530 540 550
AVDAFGTMMI PHSIISMAES ASDILEPMVL LKEFGLIKIQ EGHLTGHIDV
560 570 580 590 600
IPLFETIDDL QNGAKILQDL WQIPLYRSYL EQRGNLQEVM LGYSDSNKDG
610 620 630 640 650
GYLAANWALY AAETDLVNIC KQHGIALRLF HGRGGTVGRG GGPSYEAILA
660 670 680 690 700
QPHGAVQGSV RVTEQGEIIS AKYGSAGAAR RNLEALASAT LEASLLKIDQ
710 720 730 740 750
VEEQYPEAYE IMGEISRLSQ KKYSRLAHED PGFIEYFTSS TPLEEIGELN
760 770 780 790 800
IGSRPSSRKQ TKSIDDLRAI PWVLSWSQSR VMLPGWYGVG SALHEWIEKG
810 820 830 840 850
CAQTAELSPD ERLVVLQELN SSWPFFSSVL SNMAQVMSKA EMQLAKLYSG
860 870 880 890 900
LVADQEAANR IFSDISAEFE LTKKMFLKIT GFSGLLDDNP MLARSVRSRY
910 920 930 940
PYLLPLNTLQ LEMLRRYRKG DDDPKVVHGI RLAMNGLATA LRNSG
Length:945
Mass (Da):105,583
Last modified:January 11, 2011 - v1
Checksum:iBA661158CB5BEA2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002251 Genomic DNA. Translation: ADO26377.1.
RefSeqiWP_014522533.1. NC_017303.1.
YP_005685555.1. NC_017303.1.

Genome annotation databases

EnsemblBacteriaiADO26377; ADO26377; CpI19_1109.
GeneIDi12295474.
KEGGicpx:CpI19_1109.
PATRICi42905145. VBICorPse169742_1158.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002251 Genomic DNA. Translation: ADO26377.1.
RefSeqiWP_014522533.1. NC_017303.1.
YP_005685555.1. NC_017303.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO26377; ADO26377; CpI19_1109.
GeneIDi12295474.
KEGGicpx:CpI19_1109.
PATRICi42905145. VBICorPse169742_1158.

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciCPSE889513:GLBZ-1160-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: I19.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: I19Imported.

Entry informationi

Entry nameiE3FBC0_CORP9
AccessioniPrimary (citable) accession number: E3FBC0
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: February 4, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.