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E3F210

- E3F210_KETVY

UniProt

E3F210 - E3F210_KETVY

Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Ketogulonicigenium vulgare (strain Y25)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei47 – 471NucleophileUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Biological processi

    tRNA processingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciKVUL880591:GHQW-2844-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(55) synthaseUniRule annotation
    tRNA pseudouridylate synthaseUniRule annotation
    tRNA-uridine isomeraseUniRule annotation
    Gene namesi
    Name:truBUniRule annotationImported
    Ordered Locus Names:EIO_2845Imported
    OrganismiKetogulonicigenium vulgare (strain Y25)Imported
    Taxonomic identifieri880591 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeKetogulonicigenium
    ProteomesiUP000006871: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE3F210.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000231225.
    KOiK03177.
    OMAiNGNPGMV.

    Family and domain databases

    HAMAPiMF_01080. TruB_bact.
    InterProiIPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view]
    PANTHERiPTHR13767. PTHR13767. 1 hit.
    PfamiPF01509. TruB_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00431. TruB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E3F210-1 [UniParc]FASTAAdd to Basket

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    MARGRKGRNI SGWVIVDKPA GITSTAVVNK IRWAFDAQKA GHAGTLDPDA    50
    TGLLAVALGE ATKTIPYVTD ALKAYEFTVT FGASTSTDDA SGEVVATSDA 100
    RPTDAAIKEA LNAFVGDIMQ VPPAFSAIKI DGERAYDLAR EGQEFEIAAR 150
    PLFVESLLLV DRLDADHAVL EMTCGKGGYV RSIARDLGAA LGCYGHVLKL 200
    RRIWSSSFTL KGAVTMEQVE SLARTPALDD LLQPLEVALA DLPMVTCPEA 250
    SLTRFRNGNP ALVFPAPGLE FGDEAWVSVD GRALAIGQYR GSELHPARVI 300
    VGV 303
    Length:303
    Mass (Da):32,199
    Last modified:January 11, 2011 - v1
    Checksum:iE1BF7797674AC07E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002224 Genomic DNA. Translation: ADO43916.1.
    RefSeqiYP_003965216.1. NC_014625.1.

    Genome annotation databases

    EnsemblBacteriaiADO43916; ADO43916; EIO_2845.
    GeneIDi9873467.
    KEGGikvu:EIO_2845.
    PATRICi43498053. VBIKetVul170732_3089.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002224 Genomic DNA. Translation: ADO43916.1 .
    RefSeqi YP_003965216.1. NC_014625.1.

    3D structure databases

    ProteinModelPortali E3F210.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO43916 ; ADO43916 ; EIO_2845 .
    GeneIDi 9873467.
    KEGGi kvu:EIO_2845.
    PATRICi 43498053. VBIKetVul170732_3089.

    Phylogenomic databases

    HOGENOMi HOG000231225.
    KOi K03177.
    OMAi NGNPGMV.

    Enzyme and pathway databases

    BioCyci KVUL880591:GHQW-2844-MONOMER.

    Family and domain databases

    HAMAPi MF_01080. TruB_bact.
    InterProi IPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view ]
    PANTHERi PTHR13767. PTHR13767. 1 hit.
    Pfami PF01509. TruB_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00431. TruB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Y25Imported.

    Entry informationi

    Entry nameiE3F210_KETVY
    AccessioniPrimary (citable) accession number: E3F210
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3