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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Ketogulonicigenium vulgare (strain Y25)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei47 – 471NucleophileUniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: UniProtKB-HAMAP
  2. RNA binding Source: InterPro

GO - Biological processi

  1. RNA processing Source: InterPro
  2. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Biological processi

tRNA processingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciKVUL880591:GHQW-2844-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotationImported
Ordered Locus Names:EIO_2845Imported
OrganismiKetogulonicigenium vulgare (strain Y25)Imported
Taxonomic identifieri880591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeKetogulonicigenium
ProteomesiUP000006871 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE3F210.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

E3F210-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGRKGRNI SGWVIVDKPA GITSTAVVNK IRWAFDAQKA GHAGTLDPDA
60 70 80 90 100
TGLLAVALGE ATKTIPYVTD ALKAYEFTVT FGASTSTDDA SGEVVATSDA
110 120 130 140 150
RPTDAAIKEA LNAFVGDIMQ VPPAFSAIKI DGERAYDLAR EGQEFEIAAR
160 170 180 190 200
PLFVESLLLV DRLDADHAVL EMTCGKGGYV RSIARDLGAA LGCYGHVLKL
210 220 230 240 250
RRIWSSSFTL KGAVTMEQVE SLARTPALDD LLQPLEVALA DLPMVTCPEA
260 270 280 290 300
SLTRFRNGNP ALVFPAPGLE FGDEAWVSVD GRALAIGQYR GSELHPARVI

VGV
Length:303
Mass (Da):32,199
Last modified:January 11, 2011 - v1
Checksum:iE1BF7797674AC07E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002224 Genomic DNA. Translation: ADO43916.1.
RefSeqiWP_013385564.1. NC_014625.1.
YP_003965216.1. NC_014625.1.

Genome annotation databases

EnsemblBacteriaiADO43916; ADO43916; EIO_2845.
KEGGikvu:EIO_2845.
PATRICi43498053. VBIKetVul170732_3089.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002224 Genomic DNA. Translation: ADO43916.1.
RefSeqiWP_013385564.1. NC_014625.1.
YP_003965216.1. NC_014625.1.

3D structure databases

ProteinModelPortaliE3F210.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO43916; ADO43916; EIO_2845.
KEGGikvu:EIO_2845.
PATRICi43498053. VBIKetVul170732_3089.

Phylogenomic databases

HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.

Enzyme and pathway databases

BioCyciKVUL880591:GHQW-2844-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y25Imported.

Entry informationi

Entry nameiE3F210_KETVY
AccessioniPrimary (citable) accession number: E3F210
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: April 29, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.