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E3F1J5

- E3F1J5_KETVY

UniProt

E3F1J5 - E3F1J5_KETVY

Protein

Alanine racemase

Gene

EIO_1396

Organism
Ketogulonicigenium vulgare (strain Y25)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei33 – 331Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei128 – 1281SubstrateUniRule annotation
    Active sitei242 – 2421Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei290 – 2901Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciKVUL880591:GHQW-1396-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:EIO_1396Imported
    OrganismiKetogulonicigenium vulgare (strain Y25)Imported
    Taxonomic identifieri880591 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeKetogulonicigenium
    ProteomesiUP000006871: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei33 – 331N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE3F1J5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031445.
    KOiK01775.
    OMAiFIMSHLA.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E3F1J5-1 [UniParc]FASTAAdd to Basket

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    MTTGILTIDL DAIIGNWRKL AAMSRAEAGA VLKADAYGTG AARVGAALAE    50
    AGVRKFFVAV AEEGVALREA VGPAPEIFVL SGHGTTDTAL IRQLNLTPVL 100
    NSPQQLRRQF DALPGRPFAI QLDTGMNRLG FEWEDWAAVT DEVLGAGPRL 150
    IMSHLACADE PDHPMNAYQL DLFKQMTEGM RVSRSLAATG GILLGPDYHF 200
    DLVRPGIGLH GAAPYAQGAQ ALQLDLPVIQ TRDLIEGEVV GYGNTWQARR 250
    PTRVATLAAG YADGVLRVLG AGTNVYSGDI ACPIIGRISM DLITVDITDL 300
    DADPEVLTLI GPQQSVDDLA VTAKTIGYEI LTSLSPRYSR QYIGG 345
    Length:345
    Mass (Da):36,720
    Last modified:January 11, 2011 - v1
    Checksum:iA29BFE5D60E750B1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002224 Genomic DNA. Translation: ADO42529.1.
    RefSeqiYP_003963829.1. NC_014625.1.

    Genome annotation databases

    EnsemblBacteriaiADO42529; ADO42529; EIO_1396.
    GeneIDi9872019.
    KEGGikvu:EIO_1396.
    PATRICi43495087. VBIKetVul170732_1633.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002224 Genomic DNA. Translation: ADO42529.1 .
    RefSeqi YP_003963829.1. NC_014625.1.

    3D structure databases

    ProteinModelPortali E3F1J5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO42529 ; ADO42529 ; EIO_1396 .
    GeneIDi 9872019.
    KEGGi kvu:EIO_1396.
    PATRICi 43495087. VBIKetVul170732_1633.

    Phylogenomic databases

    HOGENOMi HOG000031445.
    KOi K01775.
    OMAi FIMSHLA.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci KVUL880591:GHQW-1396-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Y25Imported.

    Entry informationi

    Entry nameiE3F1J5_KETVY
    AccessioniPrimary (citable) accession number: E3F1J5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3