Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E3EG21

- E3EG21_PAEPS

UniProt

E3EG21 - E3EG21_PAEPS

Protein

Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO

Gene

trmFO

Organism
Paenibacillus polymyxa (strain SC2) (Bacillus polymyxa)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.UniRule annotationSAAS annotation

    Catalytic activityi

    5,10-methylenetetrahydrofolate + uracil(54) in tRNA + FADH2 = tetrahydrofolate + 5-methyluracil(54) in tRNA + FAD.UniRule annotationSAAS annotation

    Cofactori

    FAD.UniRule annotationSAAS annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi11 – 166FADUniRule annotation

    GO - Molecular functioni

    1. 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity Source: UniProtKB-HAMAP
    2. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP
    3. methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    tRNA processingUniRule annotationSAAS annotation

    Keywords - Ligandi

    FADUniRule annotationSAAS annotation, Flavoprotein

    Enzyme and pathway databases

    BioCyciPPOL886882:GBY1-2169-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFOUniRule annotation (EC:2.1.1.74UniRule annotation)
    Alternative name(s):
    Folate-dependent tRNA (uracil-5-)-methyltransferaseUniRule annotation
    Folate-dependent tRNA(M-5-U54)-methyltransferaseUniRule annotation
    Gene namesi
    Name:trmFOUniRule annotation
    Ordered Locus Names:PPSC2_c2082Imported
    OrganismiPaenibacillus polymyxa (strain SC2) (Bacillus polymyxa)Imported
    Taxonomic identifieri886882 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
    ProteomesiUP000006868: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MnmG family. TrmFO subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000252054.
    KOiK04094.
    OMAiEIYFEGC.

    Family and domain databases

    HAMAPiMF_01037. TrmFO.
    InterProiIPR004417. Folate-dep_Ribothymidyl_synth.
    IPR002218. GIDA-rel.
    IPR020595. GIDA-rel_CS.
    [Graphical view]
    PfamiPF01134. GIDA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00137. gid_trmFO. 1 hit.
    PROSITEiPS01281. GIDA_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E3EG21-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSELQKVTVI GAGLAGSEAA WQIASRGVPV KLYEMRPVVK TPAHHTDKFA    50
    ELVCSNSLRA NGLTNAVGVL KEEMRILNSL VLSAADRHAV PAGGALAVDR 100
    DGFSGHITDT LHQHPLIEVV NEELQELPQD GIVVVATGPL TSPALSEQIK 150
    TLMGEEYFYF YDAAAPIVEK DSIDMSKVYL ASRYDKGEAA YLNCPMNEAE 200
    FDAFYEALIT AEVAQVKEFE KEIYFEGCMP IEVMMQRGKQ TALFGPMKPV 250
    GLVNPHTGEL PYAVVQLRQD NAAGTLYNLV GFQTHLKWGE QKRVFSMIPG 300
    LEEAEFVRYG VMHRNTFINS PQQLHPTYQF KGRSNLFFAG QMTGVEGYVE 350
    SAASGLLAGI NAARAARGQE MFVFPAETTL GSMARYITTA DFKHFQPMNA 400
    NFGLLPKLET RIRNKKEKNE ALANRALESL RGYINQTGVM STEVQA 446
    Length:446
    Mass (Da):49,138
    Last modified:January 11, 2011 - v1
    Checksum:i2DEDEAC8EE3127C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002213 Genomic DNA. Translation: ADO56054.1.
    RefSeqiWP_013370668.1. NC_014622.1.
    YP_003946295.1. NC_014622.1.

    Genome annotation databases

    EnsemblBacteriaiADO56054; ADO56054; PPSC2_c2082.
    GeneIDi9850393.
    KEGGippm:PPSC2_c2082.
    PATRICi42507414. VBIPaePol172748_1988.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002213 Genomic DNA. Translation: ADO56054.1 .
    RefSeqi WP_013370668.1. NC_014622.1.
    YP_003946295.1. NC_014622.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO56054 ; ADO56054 ; PPSC2_c2082 .
    GeneIDi 9850393.
    KEGGi ppm:PPSC2_c2082.
    PATRICi 42507414. VBIPaePol172748_1988.

    Phylogenomic databases

    HOGENOMi HOG000252054.
    KOi K04094.
    OMAi EIYFEGC.

    Enzyme and pathway databases

    BioCyci PPOL886882:GBY1-2169-MONOMER.

    Family and domain databases

    HAMAPi MF_01037. TrmFO.
    InterProi IPR004417. Folate-dep_Ribothymidyl_synth.
    IPR002218. GIDA-rel.
    IPR020595. GIDA-rel_CS.
    [Graphical view ]
    Pfami PF01134. GIDA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00137. gid_trmFO. 1 hit.
    PROSITEi PS01281. GIDA_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity."
      Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F., Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B.
      J. Bacteriol. 193:311-312(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC2Imported.

    Entry informationi

    Entry nameiE3EG21_PAEPS
    AccessioniPrimary (citable) accession number: E3EG21
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3