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E3EG21 (E3EG21_PAEPS) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO HAMAP-Rule MF_01037
EC=2.1.1.74 HAMAP-Rule MF_01037
Alternative name(s):
Folate-dependent tRNA (uracil-5-)-methyltransferase HAMAP-Rule MF_01037
Folate-dependent tRNA(M-5-U54)-methyltransferase HAMAP-Rule MF_01037
Gene names
Name:trmFO HAMAP-Rule MF_01037
Ordered Locus Names:PPSC2_c2082 EMBL ADO56054.1
OrganismPaenibacillus polymyxa (strain SC2) (Bacillus polymyxa) [Complete proteome] [HAMAP]
Taxonomic identifier886882 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Paenibacillaceae › Paenibacillus ›

Protein attributes

Sequence length446 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs By similarity. HAMAP-Rule MF_01037 SAAS SAAS004417

Catalytic activity

5,10-methylenetetrahydrofolate + uridine54 in tRNA + FADH2 = tetrahydrofolate + 5-methyluridine54 in tRNA + FAD. HAMAP-Rule MF_01037 SAAS SAAS004417

Cofactor

FAD By similarity. HAMAP-Rule MF_01037 SAAS SAAS004417

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01037 SAAS SAAS004417.

Sequence similarities

Belongs to the MnmG family. TrmFO subfamily. HAMAP-Rule MF_01037

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding11 – 166FAD By similarity HAMAP-Rule MF_01037

Sequences

Sequence LengthMass (Da)Tools
E3EG21 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 2DEDEAC8EE3127C7

FASTA44649,138
        10         20         30         40         50         60 
MSELQKVTVI GAGLAGSEAA WQIASRGVPV KLYEMRPVVK TPAHHTDKFA ELVCSNSLRA 

        70         80         90        100        110        120 
NGLTNAVGVL KEEMRILNSL VLSAADRHAV PAGGALAVDR DGFSGHITDT LHQHPLIEVV 

       130        140        150        160        170        180 
NEELQELPQD GIVVVATGPL TSPALSEQIK TLMGEEYFYF YDAAAPIVEK DSIDMSKVYL 

       190        200        210        220        230        240 
ASRYDKGEAA YLNCPMNEAE FDAFYEALIT AEVAQVKEFE KEIYFEGCMP IEVMMQRGKQ 

       250        260        270        280        290        300 
TALFGPMKPV GLVNPHTGEL PYAVVQLRQD NAAGTLYNLV GFQTHLKWGE QKRVFSMIPG 

       310        320        330        340        350        360 
LEEAEFVRYG VMHRNTFINS PQQLHPTYQF KGRSNLFFAG QMTGVEGYVE SAASGLLAGI 

       370        380        390        400        410        420 
NAARAARGQE MFVFPAETTL GSMARYITTA DFKHFQPMNA NFGLLPKLET RIRNKKEKNE 

       430        440 
ALANRALESL RGYINQTGVM STEVQA

« Hide

References

[1]"Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity."
Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F., Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B.
J. Bacteriol. 193:311-312(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002213 Genomic DNA. Translation: ADO56054.1.
RefSeqYP_003946295.1. NC_014622.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO56054; ADO56054; PPSC2_c2082.
GeneID9850393.
KEGGppm:PPSC2_c2082.
PATRIC42507414. VBIPaePol172748_1988.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000252054.
KOK04094.
OMARFAGQIT.

Family and domain databases

HAMAPMF_01037. TrmFO.
InterProIPR004417. Folate-dep_Ribothymidyl_synth.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamPF01134. GIDA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00137. gid_trmFO. 1 hit.
PROSITEPS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3EG21_PAEPS
AccessionPrimary (citable) accession number: E3EG21
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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