Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E3ECX2

- E3ECX2_PAEPS

UniProt

E3ECX2 - E3ECX2_PAEPS

Protein

Amidophosphoribosyltransferase

Gene

PPSC2_c0858

Organism
Paenibacillus polymyxa (strain SC2) (Bacillus polymyxa)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O.UniRule annotation

    Cofactori

    Binds 1 4Fe-4S cluster per subunit.UniRule annotation
    Binds 1 magnesium ion per subunit.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei33 – 331For GATase activityUniRule annotation
    Metal bindingi267 – 2671Iron-sulfur (4Fe-4S)
    Metal bindingi413 – 4131Iron-sulfur (4Fe-4S)
    Metal bindingi469 – 4691Iron-sulfur (4Fe-4S)
    Metal bindingi472 – 4721Iron-sulfur (4Fe-4S)

    GO - Molecular functioni

    1. amidophosphoribosyltransferase activity Source: UniProtKB-EC
    2. iron-sulfur cluster binding Source: UniProtKB-KW
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
    2. nucleoside metabolic process Source: InterPro
    3. purine nucleobase biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    GlycosyltransferaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    Purine biosynthesisUniRule annotation

    Keywords - Ligandi

    Iron, Iron-sulfurUniRule annotation, MagnesiumUniRule annotation, Metal-binding

    Enzyme and pathway databases

    BioCyciPPOL886882:GBY1-933-MONOMER.
    UniPathwayiUPA00074; UER00124.

    Protein family/group databases

    MEROPSiC44.001.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AmidophosphoribosyltransferaseUniRule annotation (EC:2.4.2.14UniRule annotation)
    Short name:
    ATaseUniRule annotation
    Alternative name(s):
    Glutamine phosphoribosylpyrophosphate amidotransferaseUniRule annotation
    Gene namesi
    Ordered Locus Names:PPSC2_c0858Imported
    OrganismiPaenibacillus polymyxa (strain SC2) (Bacillus polymyxa)Imported
    Taxonomic identifieri886882 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
    ProteomesiUP000006868: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE3ECX2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000033688.
    KOiK00764.
    OMAiSGIPYEM.

    Family and domain databases

    Gene3Di3.40.50.2020. 1 hit.
    3.60.20.10. 1 hit.
    InterProiIPR005854. Amd_phspho_trans.
    IPR017932. GATase_2_dom.
    IPR000583. GATase_dom.
    IPR029055. Ntn_hydrolases_N.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view]
    PfamiPF13537. GATase_7. 1 hit.
    PF00156. Pribosyltran. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000485. Amd_phspho_trans. 1 hit.
    SUPFAMiSSF53271. SSF53271. 1 hit.
    SSF56235. SSF56235. 1 hit.
    TIGRFAMsiTIGR01134. purF. 1 hit.
    PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E3ECX2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDEITARTL WTGDYYNEGS GKEGLFDKLK EECGVFGVYR HSDAASLAYY    50
    GLHALQHRGE ESAGICVSSG DEFHYHRGMG LVKEVFNKDL MASLTGDIAI 100
    GHVRYSTSGD SKLTNAQPLV FKYRDGDLAV ATNGNIVNAL QIRHELEQGG 150
    SIFQTTSDTE VVAHLIARSS KDLVEAAKDA LKRIVGGFAF LIMTNDKLLV 200
    ASDPNGLRPL TMGRLGDAYL FASESCALET IGAELLRDIE PGELLILDKN 250
    GLHEDRYTED KQRKALCAME YIYFARPDSD LNGANLHAAR KRMGSQLALE 300
    AFVDADLVTG VPDSSISAAI GYAEQTGIPY ELGMIKNKYT GRTFIQPSQE 350
    LREQGVKMKL SAVRRVVEGK RVIMIDDSIV RGTTSRRIVN MLRDAGALEV 400
    HVRITSPPFK NPCFYGIDTP DRRELIASSK TVEEIRQEIN ADSLFFMSAE 450
    GLIAAVGGHN EQDYKGGLCL ACFDNDYPTQ VDFKGEEKFG CSC 493
    Length:493
    Mass (Da):54,175
    Last modified:January 11, 2011 - v1
    Checksum:iB0E2327A471F1ACA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002213 Genomic DNA. Translation: ADO54841.1.
    RefSeqiWP_013369475.1. NC_014622.1.
    YP_003945082.1. NC_014622.1.

    Genome annotation databases

    EnsemblBacteriaiADO54841; ADO54841; PPSC2_c0858.
    GeneIDi9849180.
    KEGGippm:PPSC2_c0858.
    PATRICi42505074. VBIPaePol172748_0828.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002213 Genomic DNA. Translation: ADO54841.1 .
    RefSeqi WP_013369475.1. NC_014622.1.
    YP_003945082.1. NC_014622.1.

    3D structure databases

    ProteinModelPortali E3ECX2.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi C44.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO54841 ; ADO54841 ; PPSC2_c0858 .
    GeneIDi 9849180.
    KEGGi ppm:PPSC2_c0858.
    PATRICi 42505074. VBIPaePol172748_0828.

    Phylogenomic databases

    HOGENOMi HOG000033688.
    KOi K00764.
    OMAi SGIPYEM.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00124 .
    BioCyci PPOL886882:GBY1-933-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.2020. 1 hit.
    3.60.20.10. 1 hit.
    InterProi IPR005854. Amd_phspho_trans.
    IPR017932. GATase_2_dom.
    IPR000583. GATase_dom.
    IPR029055. Ntn_hydrolases_N.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view ]
    Pfami PF13537. GATase_7. 1 hit.
    PF00156. Pribosyltran. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000485. Amd_phspho_trans. 1 hit.
    SUPFAMi SSF53271. SSF53271. 1 hit.
    SSF56235. SSF56235. 1 hit.
    TIGRFAMsi TIGR01134. purF. 1 hit.
    PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity."
      Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F., Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B.
      J. Bacteriol. 193:311-312(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC2Imported.

    Entry informationi

    Entry nameiE3ECX2_PAEPS
    AccessioniPrimary (citable) accession number: E3ECX2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3