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E3ECW3 (E3ECW3_PAEPS) Unreviewed, UniProtKB/TrEMBL

Last modified December 11, 2013. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N5-carboxyaminoimidazole ribonucleotide mutase PIRNR PIRNR001338

Short name=N5-CAIR mutase PIRNR PIRNR001338
EC=5.4.99.18 PIRNR PIRNR001338
Gene names
Ordered Locus Names:PPSC2_c0849 EMBL ADO54832.1
OrganismPaenibacillus polymyxa (strain SC2) (Bacillus polymyxa) [Complete proteome] [HAMAP] EMBL ADO54832.1
Taxonomic identifier886882 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length161 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) By similarity. PIRNR PIRNR001338

Catalytic activity

5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. PIRNR PIRNR001338

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. PIRNR PIRNR001338

Sequence similarities

Belongs to the AIR carboxylase family. PIRNR PIRNR001338

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site111Substrate By similarity PIRSR PIRSR001338-1
Binding site141Substrate By similarity PIRSR PIRSR001338-1
Binding site411Substrate By similarity PIRSR PIRSR001338-1

Sequences

Sequence LengthMass (Da)Tools
E3ECW3 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 4967E58A7864DCEC

FASTA16116,718
        10         20         30         40         50         60 
MSVQVAVIMG STSDWDTMQH ACAVLDELEI GYEKKVVSAH RTPDLMFRFA EEAAGRGLKV 

        70         80         90        100        110        120 
IIAGAGGAAH LPGMVAAKTS LPVIGVPVQS KALNGLDSLL SIVQMPGGIP VATVAIGKAG 

       130        140        150        160 
STNAGLLAAQ ILGAFDEKIS QRVVARRDRI RDEVLEGSDS L 

« Hide

References

[1]"Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity."
Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F., Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B.
J. Bacteriol. 193:311-312(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC2 EMBL ADO54832.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002213 Genomic DNA. Translation: ADO54832.1.
RefSeqYP_003945073.1. NC_014622.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO54832; ADO54832; PPSC2_c0849.
GeneID9849171.
KEGGppm:PPSC2_c0849.
PATRIC42505058. VBIPaePol172748_0820.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000034141.
KOK01588.
OMAKHACDIL.

Enzyme and pathway databases

BioCycPPOL886882:GBY1-924-MONOMER.
UniPathwayUPA00074; UER00943.

Family and domain databases

Gene3D3.40.50.7700. 1 hit.
InterProIPR024694. N5-CAIR_mutase_PurE.
IPR000031. PurE_dom.
[Graphical view]
PfamPF00731. AIRC. 1 hit.
[Graphical view]
PIRSFPIRSF001338. AIR_carboxylase. 1 hit.
SMARTSM01001. AIRC. 1 hit.
[Graphical view]
SUPFAMSSF52255. SSF52255. 1 hit.
TIGRFAMsTIGR01162. purE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE3ECW3_PAEPS
AccessionPrimary (citable) accession number: E3ECW3
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: December 11, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)