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E3EBS4 (E3EBS4_PAEPS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase HAMAP-Rule MF_00111

EC=2.5.1.7 HAMAP-Rule MF_00111
Alternative name(s):
Enoylpyruvate transferase HAMAP-Rule MF_00111
UDP-N-acetylglucosamine enolpyruvyl transferase HAMAP-Rule MF_00111
Gene names
Name:murA HAMAP-Rule MF_00111
Ordered Locus Names:PPSC2_c4953 EMBL ADO58892.1
OrganismPaenibacillus polymyxa (strain SC2) (Bacillus polymyxa) [Complete proteome] [HAMAP]
Taxonomic identifier886882 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length453 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. SAAS SAAS005750 HAMAP-Rule MF_00111

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. SAAS SAAS005750 HAMAP-Rule MF_00111

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005750 HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity SAAS SAAS005750 HAMAP-Rule MF_00111.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily. HAMAP-Rule MF_00111

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1171Proton donor By similarity HAMAP-Rule MF_00111

Amino acid modifications

Modified residue11712-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity HAMAP-Rule MF_00111

Sequences

Sequence LengthMass (Da)Tools
E3EBS4 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 3A65A50C495D5AF2

FASTA45348,266
        10         20         30         40         50         60 
MSKFIVRGGN RLTGSVKVSG AKNSVLPIIA ASLLGEEGES VIMDAPPLDD VMTINKVLES 

        70         80         90        100        110        120 
LGAGVTYQDE VIRVDARKII SCEAPYEWVR KMRASFLVMG PLLTRLGRTR ISLPGGCAIG 

       130        140        150        160        170        180 
TRPIDQHLKG FEALGAEISL GQGFIEAKSN GRLRGAKVYL DVASVGATEN IMMAATLAEG 

       190        200        210        220        230        240 
VTTIENAAKE PEIVDLANFL NGMGAKVRGA GTGVIRIEGV EKLHGVKHTV IPDRVEAGTY 

       250        260        270        280        290        300 
MVAAAITGGN VYVEGAISDH LGPVISKMEE MGVTIQPDEN GIRVIADKPL KAVDVKTLPY 

       310        320        330        340        350        360 
PGFPTDMQSQ MMALQLAAEG TSIITETVFE NRFMHVDEFH LMNAEIKVEG RSAIVTGNAK 

       370        380        390        400        410        420 
LTGAKVTSTD LRAGAALILT GLIAEGTTEV SGVHHIDRGY VHLAEKLTGL GADIYRVTVD 

       430        440        450 
ESKLDHSAST ERVGQKKRRG ICSRRFSLPS PNL 

« Hide

References

[1]"Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity."
Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F., Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B.
J. Bacteriol. 193:311-312(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002213 Genomic DNA. Translation: ADO58892.1.
RefSeqYP_003949133.1. NC_014622.1.

3D structure databases

ProteinModelPortalE3EBS4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO58892; ADO58892; PPSC2_c4953.
GeneID9853230.
KEGGppm:PPSC2_c4953.
PATRIC42513032. VBIPaePol172748_4739.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000075602.
KOK00790.
OMAGYEHIED.

Enzyme and pathway databases

BioCycPPOL886882:GBY1-5103-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. SSF55205. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE3EBS4_PAEPS
AccessionPrimary (citable) accession number: E3EBS4
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: February 19, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)