E3EAR1 (E3EAR1_PAEPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP-Rule MF_00006
Short name=ASAL HAMAP-Rule MF_00006
EC=4.3.2.1 HAMAP-Rule MF_00006

Alternative name(s):
Arginosuccinase HAMAP-Rule MF_00006

Gene names

Name:	argH HAMAP-Rule MF_00006
Ordered Locus Names:	PPSC2_c4878 EMBL ADO58819.1

Organism

Paenibacillus polymyxa (strain SC2) (Bacillus polymyxa) [Complete proteome] [HAMAP]

Taxonomic identifier

886882 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Paenibacillaceae › Paenibacillus › Paenibacillus polymyxa

Protein attributes

Sequence length	470 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP-Rule MF_00006 SAAS SAAS009049
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP-Rule MF_00006 SAAS SAAS009049
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00006 SAAS SAAS009049.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP-Rule MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP-Rule MF_00006 SAAS SAAS009049
Cellular component	Cytoplasm HAMAP-Rule MF_00006 SAAS SAAS009049
Molecular function	Lyase HAMAP-Rule MF_00006 SAAS SAAS009049 EMBL ADO58819.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E3EAR1 [UniParc]. Last modified January 11, 2011. Version 1. Checksum: BDD798A11F521B40	FASTA	470	52,288
	10 20 30 40 50 60 MSKLWGGRFT KQTNKLVEEY TASIGFDQAL AEEDIQGSLA HVAMLGKCGI IPQEDADTIK 70 80 90 100 110 120 GGLHTVLERI RRGEIEFSVS DEDIHMNIEK NLIEVIGPVG GKLHTGRSRN DQVATDMHLY 130 140 150 160 170 180 LRGRVVSLVG MLHDVQVALI GQAKDNLDTI VPGYTHLQRA QPILFAHHLL AYVSMLERDI 190 200 210 220 230 240 DRLKDSYKRI NVLPLGAGAL AGTTFPIDRH FVAEQLGFDG VYENSLDAVS DRDFIVEFLA 250 260 270 280 290 300 GASLIMTHLS RLSEELVLWS STEFGFVELD DAFCTGSSIM PQKKNPDVPE LVRGKTGRVY 310 320 330 340 350 360 GNLVGLLTVL KSLPLAYNKD MQEDKEGMFD TIATLEGALQ LFAPMIATMK VNKDRMRQAV 370 380 390 400 410 420 NQDFSNATDI ADFLVGKGLP FRQAHEVIGK TVLYCIQQGK YLLDLKLDEF QQFSDLFDER 430 440 450 460 470 IYEVLQPEAV VNARNVYGGT ATGQVQAAIG RSEQLLVNTS TWYENHKPKK

References

[1]

"Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity." Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F., Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B. J. Bacteriol. 193:311-312(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002213 Genomic DNA. Translation: ADO58819.1.
RefSeq	YP_003949060.1. NC_014622.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADO58819; ADO58819; PPSC2_c4878.
GeneID	9853157.
KEGG	ppm:PPSC2_c4878.
PATRIC	42512890. VBIPaePol172748_4668.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000242744.
KO	K01755.
OMA	EDIHTVI.
Enzyme and pathway databases
UniPathway	UPA00068; UER00114.
Family and domain databases
Gene3D	1.10.275.10. 1 hit.
HAMAP	MF_00006. Arg_succ_lyase.
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR024083. Fumarase/histidase_N. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR022761. Fumarate_lyase_N. IPR008948. L-Aspartase-like. [Graphical view]
PANTHER	PTHR11444:SF3. PTHR11444:SF3. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. argH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E3EAR1_PAEPS

Accession

Primary (citable) accession number: E3EAR1

Entry history

Integrated into UniProtKB/TrEMBL:	January 11, 2011
Last sequence update:	January 11, 2011
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)