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Protein

Protein RecA

Gene

recA

Organism
Gardnerella vaginalis (strain ATCC 14019 / 317)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi83 – 908ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. damaged DNA binding Source: UniProtKB-HAMAP
  3. DNA-dependent ATPase activity Source: UniProtKB-HAMAP
  4. single-stranded DNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA recombination Source: UniProtKB-HAMAP
  2. DNA repair Source: UniProtKB-HAMAP
  3. SOS response Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repair, SOS responseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, DNA-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciGVAG525284:GI3V-902-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotationImported
Ordered Locus Names:HMPREF0421_20867Imported
OrganismiGardnerella vaginalis (strain ATCC 14019 / 317)Imported
Taxonomic identifieri525284 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeGardnerella
ProteomesiUP000001453 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliE3DA55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000264120.
KOiK03553.
OMAiSMIKESI.
OrthoDBiEOG6ZKXNZ.

Family and domain databases

Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3DA55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQQAKKGAV DRLIDADKAD PRRKAALETA LANVEKQYGK GSAMRLGDKP
60 70 80 90 100
LQDVEVIPTG SIALDMALGI GGVPRGRIVE VYGPESSGKT TLALHIVANA
110 120 130 140 150
QKNGGIAAFI DAEHALDPVY ARKLGVDTDS LIVSQPDNGE QALEIADMLI
160 170 180 190 200
RSGALDVIVV DSVAALVPKA EIDGDMGDSH VGLQARLMSQ ALRKMTGALS
210 220 230 240 250
QAGTTAIFIN QLREKIGVFF GNPETTTGGK ALKFYSSVRM DIRRVSTIKN
260 270 280 290 300
GEEAVGNRTK VKIVKNKMAP PFKTAEFDVL YGEGISTEGS VIDMAVQCDV
310 320 330 340 350
IKKSGSWFTY EGEQLGQGRE NVRQFLKDNP AITEEISDKV KVAFGLMKPE
360 370 380
DQFVEVEDED DNSQSVSSSS ADSKTNTSKG SDVK
Length:384
Mass (Da):41,079
Last modified:January 11, 2011 - v1
Checksum:i7A32F4E51E18CA2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002104 Genomic DNA. Translation: ADP38949.1.
RefSeqiYP_003985972.1. NC_014644.1.

Genome annotation databases

EnsemblBacteriaiADP38949; ADP38949; HMPREF0421_20867.
GeneIDi9904435.
KEGGigvg:HMPREF0421_20867.
PATRICi42628613. VBIGarVag39333_0856.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002104 Genomic DNA. Translation: ADP38949.1.
RefSeqiYP_003985972.1. NC_014644.1.

3D structure databases

ProteinModelPortaliE3DA55.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADP38949; ADP38949; HMPREF0421_20867.
GeneIDi9904435.
KEGGigvg:HMPREF0421_20867.
PATRICi42628613. VBIGarVag39333_0856.

Phylogenomic databases

HOGENOMiHOG000264120.
KOiK03553.
OMAiSMIKESI.
OrthoDBiEOG6ZKXNZ.

Enzyme and pathway databases

BioCyciGVAG525284:GI3V-902-MONOMER.

Family and domain databases

Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
    Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
    PLoS ONE 5:E12411-E12411(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14019 / 317Imported.

Entry informationi

Entry nameiE3DA55_GARV3
AccessioniPrimary (citable) accession number: E3DA55
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: April 29, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.