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E3D9A0 (E3D9A0_GARV3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
DNA-directed DNA polymerase I EMBL ADP38644.1
EC=2.7.7.7 EMBL ADP38644.1
Gene names
Name:polA
Ordered Locus Names:HMPREF0421_20562
OrganismGardnerella vaginalis (strain ATCC 14019 / 317) [Complete proteome] [HAMAP]
Taxonomic identifier525284 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Gardnerella ›

Protein attributes

Sequence length1033 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the DNA polymerase type-A family. RuleBase RU004459

Contains 1 5'-3' exonuclease domain. SAAS SAAS002421

Sequences

Sequence LengthMass (Da)Tools
E3D9A0 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 66CF150DF4D53117

FASTA1,033115,380
        10         20         30         40         50         60 
MNASIVANED SLNNEDENGT LLVVDGHSLA FRAFYAISAD NFSTKSGFAT NAIWGFSTML 

        70         80         90        100        110        120 
SQVIEKEKPD KLAVAFDVKG GTFRNKLLPQ YKGTREAAPE ELLAQLPVIQ ELLNALGVKY 

       130        140        150        160        170        180 
ITKQGYEGDD IIATLATMGA KAKYKTLVLS GDRDAFQLID EYINVLYPGR HFKDLKQMDT 

       190        200        210        220        230        240 
DAIIEKYNVT PKQYSDLAAL RGETSDNIPG VPGVGDGYAA KWINQFGGLE GIIEHADQVT 

       250        260        270        280        290        300 
GKKGESLRES IDQIRLNKKV NTLVKDLDLG VGINDLEFGN VDAASVGELF ERLEFGTRSR 

       310        320        330        340        350        360 
RKILKEFTRG SKELLEENIK MMISAGSTHA GSDVSSTESD NSDDLEDFKT IVDKINIHKI 

       370        380        390        400        410        420 
YSESDLDNWI NLVSPCIEKS ESNGSSELVK ENTEYKSKAT VDLFELLESQ EKPSLNLIRN 

       430        440        450        460        470        480 
DLECAKTIKD HKELVIYALQ KPNDSSQFGI YADVLVMLSQ NNAAIVYSDV LNGDSSEDCN 

       490        500        510        520        530        540 
KICHKLKDFI KMYESSIVLH DYKKHIALLK SLKIVDNNYS FNPLLDTRLA SYLIEPDFRN 

       550        560        570        580        590        600 
ENIEDMAEHV LNIHVENEKS NEEPAQGELD FVLEDSDNPE ELNQEEDKRK KQEKRILETA 

       610        620        630        640        650        660 
ITIRLLAKQY AIKLDERKQT GLMVDVEMPV SRVLRGMEDA GAAVDMSRLV SMRDNFAAEA 

       670        680        690        700        710        720 
QFAQKMALDV ANKPINLQSP KQLQQLLFED MGLKPTRRTK SGSYTTNAEA LQELYAKIDP 

       730        740        750        760        770        780 
DEKASQFLGA LLKHRETNKL KQIVQSLIDS ARYEDGRIHT TFEQTIAATG RLSSSDPNLQ 

       790        800        810        820        830        840 
NIPNRNVVGR EIRAAFIPGN QYDQLMSCDY SQVELRIMAH ASADETLIKA FKSGVDFHKF 

       850        860        870        880        890        900 
VASLVYKIPV EQVSPDQRSH VKAMSYGLAY GLSTYGLAKQ LSISPAAAEV LKEKYFDTFG 

       910        920        930        940        950        960 
GVHDYLESLV DKARKLGYTQ TMFGRRRYFP KLNSTNRASR ESAERAALNA PIQGSAADIM 

       970        980        990       1000       1010       1020 
KLAMIQVDKD LREAKVKSRV ILQIHDELVL EIAHGEADIV ENIVKNAMEH TVELDVPLNV 

      1030 
STGLGADWQL AAH

« Hide

References

[1]"Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
PLoS ONE 5:E12411-E12411(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14019 / 317.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002104 Genomic DNA. Translation: ADP38644.1.
RefSeqYP_003985667.1. NC_014644.1.

3D structure databases

ProteinModelPortalE3D9A0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP38644; ADP38644; HMPREF0421_20562.
GeneID9904117.
KEGGgvg:HMPREF0421_20562.
PATRIC42627997. VBIGarVag39333_0560.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000020997.
KOK02335.

Enzyme and pathway databases

BioCycGVAG525284:GI3V-584-MONOMER.

Family and domain databases

InterProIPR020046. 5-3_exonucl_a-hlix_arch_N.
IPR020045. 5-3_exonuclease_C.
IPR002421. 5-3_exonuclease_N.
IPR019760. DNA-dir_DNA_pol_A_CS.
IPR001098. DNA-dir_DNA_pol_A_palm_dom.
IPR018320. DNA_polymerase_1.
IPR002298. DNA_polymerase_A.
IPR008918. HhH2.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamPF01367. 5_3_exonuc. 1 hit.
PF02739. 5_3_exonuc_N. 1 hit.
PF00476. DNA_pol_A. 1 hit.
[Graphical view]
PRINTSPR00868. DNAPOLI.
SMARTSM00475. 53EXOc. 1 hit.
SM00279. HhH2. 1 hit.
SM00482. POLAc. 1 hit.
[Graphical view]
SUPFAMSSF47807. 5_3_exo_C. 1 hit.
SSF53098. RNaseH_fold. 1 hit.
TIGRFAMsTIGR00593. pola. 1 hit.
PROSITEPS00447. DNA_POLYMERASE_A. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3D9A0_GARV3
AccessionPrimary (citable) accession number: E3D9A0
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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