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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Gardnerella vaginalis (strain ATCC 14019 / 317)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.SAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.SAAS annotation

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, LyaseSAAS annotationImported, Transferase

Keywords - Biological processi

Carbon dioxide fixationSAAS annotation

Keywords - Ligandi

MagnesiumSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciGVAG525284:GI3V-158-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseSAAS annotation (EC:4.1.1.31SAAS annotation)
Gene namesi
Name:ppcImported
Ordered Locus Names:HMPREF0421_20155Imported
OrganismiGardnerella vaginalis (strain ATCC 14019 / 317)Imported
Taxonomic identifieri525284 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeGardnerella
ProteomesiUP000001453 Componenti: Chromosome

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiNYVETQK.
OrthoDBiEOG6TJ7T8.

Family and domain databases

InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3D7T3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTQNQQVTP ADATIVTSGL GRKGPEEREL PASLKQDMDL CLHILRDVLG
60 70 80 90 100
EFDEKLLTVF DEVRLNAVNA STAHFAQMVD AQGTEDDGLN KAVEKINGMD
110 120 130 140 150
LPDMQLLARA FATYFHLANL CEENYRVSVL HQRECEVEES NPVDPVNELT
160 170 180 190 200
CAYHKLLTEM SPAQAKELLN KLEFHPVFTA HPTEARRKAV AGKIRRISKL
210 220 230 240 250
LSKHNRLGGS DKRENYRRLY NEIDALLRTS PIALKKPTPV EEADTILDIF
260 270 280 290 300
DATLFNTIPL VYRRFDDWLL GKKAGLVPPR CPAFFHPGSW IGSDRDGNPN
310 320 330 340 350
VTAKVSRQVA SKFSNHVLKA LEERTREVGK CLTMETRTTP PSVELLELWN
360 370 380 390 400
RQREMSEQLT ENASDVSNSE PHRAVMLVMA DRLHHTISRN TDLMYHSCEE
410 420 430 440 450
FIEDLRIVQR SLAEAGDARA AYGPLQDLIW QAQTFGFHMV EMEFRQHSLV
460 470 480 490 500
HSRALEDIRE HGLHGERGPL QPMTREVLDT FRALGAIQKR NGMRAARRYI
510 520 530 540 550
ISFAKSAQHV RDVFELNRLA FAHPQDAPTI DVIPLFEQLE DLQNSVNVLE
560 570 580 590 600
EIIKIPEVQA RLKATGRKME VMLGYSDSSK DAGPTSATLA LHSAQERIAQ
610 620 630 640 650
WAKDHDIDLT LFHGRGGAVG RGGGPANRAV LAQPVGSVNC RFKLTEQGEV
660 670 680 690 700
IFARYGNPIL AIRHLESVAA ATLLQSAPSV EKTNTEMTHK YADMAQKLDV
710 720 730 740 750
AAHNRFIDLL QTDDFTPWFS TVTPLSEIGL LPIGSRPAKR GLGAKSLDDL
760 770 780 790 800
RTIPWVFSWA QARINLAAWY GLGTACEKFG DLETLRRAYE EWPLFSTFID
810 820 830 840 850
NIEMSLAKTD ERIARMYLSL GDREDLSDKV LSEMQLTRKW VLQIVGDKWP
860 870 880 890 900
LQHRHVLGQA IRVRSPYVDA LSVIQSLALH KLRNKVDKEE LSESQQAEFI
910
YLILCTVSGV AAGLQNTG
Length:918
Mass (Da):103,252
Last modified:January 11, 2011 - v1
Checksum:iB503CE7CE964BC27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002104 Genomic DNA. Translation: ADP38241.1.
RefSeqiWP_004116485.1. NC_014644.1.
YP_003985264.1. NC_014644.1.

Genome annotation databases

EnsemblBacteriaiADP38241; ADP38241; HMPREF0421_20155.
GeneIDi9903691.
KEGGigvg:HMPREF0421_20155.
PATRICi42627141. VBIGarVag39333_0151.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002104 Genomic DNA. Translation: ADP38241.1.
RefSeqiWP_004116485.1. NC_014644.1.
YP_003985264.1. NC_014644.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADP38241; ADP38241; HMPREF0421_20155.
GeneIDi9903691.
KEGGigvg:HMPREF0421_20155.
PATRICi42627141. VBIGarVag39333_0151.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiNYVETQK.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciGVAG525284:GI3V-158-MONOMER.

Family and domain databases

InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
    Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
    PLoS ONE 5:E12411-E12411(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14019 / 317Imported.

Entry informationi

Entry nameiE3D7T3_GARV3
AccessioniPrimary (citable) accession number: E3D7T3
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: June 24, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.