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E3D7T3

- E3D7T3_GARV3

UniProt

E3D7T3 - E3D7T3_GARV3

Protein
Submitted name:

Phosphoenolpyruvate carboxykinase (GTP)

Gene

ppc

Organism
Gardnerella vaginalis (strain ATCC 14019 / 317)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.SAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.SAAS annotation

    Cofactori

    Magnesium.SAAS annotation

    GO - Molecular functioni

    1. kinase activity Source: UniProtKB-KW
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    KinaseImported, LyaseSAAS annotationImported, Transferase

    Keywords - Biological processi

    Carbon dioxide fixationSAAS annotation

    Keywords - Ligandi

    MagnesiumSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciGVAG525284:GI3V-158-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Phosphoenolpyruvate carboxykinase (GTP)Imported (EC:4.1.1.31Imported)
    Gene namesi
    Name:ppcImported
    Ordered Locus Names:HMPREF0421_20155Imported
    OrganismiGardnerella vaginalis (strain ATCC 14019 / 317)Imported
    Taxonomic identifieri525284 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeGardnerella
    ProteomesiUP000001453: Chromosome

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000238647.
    KOiK01595.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 2 hits.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E3D7T3-1 [UniParc]FASTAAdd to Basket

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    MTTQNQQVTP ADATIVTSGL GRKGPEEREL PASLKQDMDL CLHILRDVLG    50
    EFDEKLLTVF DEVRLNAVNA STAHFAQMVD AQGTEDDGLN KAVEKINGMD 100
    LPDMQLLARA FATYFHLANL CEENYRVSVL HQRECEVEES NPVDPVNELT 150
    CAYHKLLTEM SPAQAKELLN KLEFHPVFTA HPTEARRKAV AGKIRRISKL 200
    LSKHNRLGGS DKRENYRRLY NEIDALLRTS PIALKKPTPV EEADTILDIF 250
    DATLFNTIPL VYRRFDDWLL GKKAGLVPPR CPAFFHPGSW IGSDRDGNPN 300
    VTAKVSRQVA SKFSNHVLKA LEERTREVGK CLTMETRTTP PSVELLELWN 350
    RQREMSEQLT ENASDVSNSE PHRAVMLVMA DRLHHTISRN TDLMYHSCEE 400
    FIEDLRIVQR SLAEAGDARA AYGPLQDLIW QAQTFGFHMV EMEFRQHSLV 450
    HSRALEDIRE HGLHGERGPL QPMTREVLDT FRALGAIQKR NGMRAARRYI 500
    ISFAKSAQHV RDVFELNRLA FAHPQDAPTI DVIPLFEQLE DLQNSVNVLE 550
    EIIKIPEVQA RLKATGRKME VMLGYSDSSK DAGPTSATLA LHSAQERIAQ 600
    WAKDHDIDLT LFHGRGGAVG RGGGPANRAV LAQPVGSVNC RFKLTEQGEV 650
    IFARYGNPIL AIRHLESVAA ATLLQSAPSV EKTNTEMTHK YADMAQKLDV 700
    AAHNRFIDLL QTDDFTPWFS TVTPLSEIGL LPIGSRPAKR GLGAKSLDDL 750
    RTIPWVFSWA QARINLAAWY GLGTACEKFG DLETLRRAYE EWPLFSTFID 800
    NIEMSLAKTD ERIARMYLSL GDREDLSDKV LSEMQLTRKW VLQIVGDKWP 850
    LQHRHVLGQA IRVRSPYVDA LSVIQSLALH KLRNKVDKEE LSESQQAEFI 900
    YLILCTVSGV AAGLQNTG 918
    Length:918
    Mass (Da):103,252
    Last modified:January 11, 2011 - v1
    Checksum:iB503CE7CE964BC27
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002104 Genomic DNA. Translation: ADP38241.1.
    RefSeqiYP_003985264.1. NC_014644.1.

    Genome annotation databases

    EnsemblBacteriaiADP38241; ADP38241; HMPREF0421_20155.
    GeneIDi9903691.
    KEGGigvg:HMPREF0421_20155.
    PATRICi42627141. VBIGarVag39333_0151.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002104 Genomic DNA. Translation: ADP38241.1 .
    RefSeqi YP_003985264.1. NC_014644.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADP38241 ; ADP38241 ; HMPREF0421_20155 .
    GeneIDi 9903691.
    KEGGi gvg:HMPREF0421_20155.
    PATRICi 42627141. VBIGarVag39333_0151.

    Phylogenomic databases

    HOGENOMi HOG000238647.
    KOi K01595.
    OrthoDBi EOG6TJ7T8.

    Enzyme and pathway databases

    BioCyci GVAG525284:GI3V-158-MONOMER.

    Family and domain databases

    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 2 hits.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
      Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
      PLoS ONE 5:E12411-E12411(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 14019 / 317Imported.

    Entry informationi

    Entry nameiE3D7T3_GARV3
    AccessioniPrimary (citable) accession number: E3D7T3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3