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E3D3X1

- E3D3X1_NEIM7

UniProt

E3D3X1 - E3D3X1_NEIM7

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, NMBB_2367
Organism
Neisseria meningitidis serogroup B (strain alpha710)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei157 – 1571 By similarityUniRule annotation
Active sitei585 – 5851 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciNMEN630588:GLHP-2046-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:NMBB_2367Imported
OrganismiNeisseria meningitidis serogroup B (strain alpha710)Imported
Taxonomic identifieri630588 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000006929: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3D3X1-1 [UniParc]FASTAAdd to Basket

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MRHLRYIYSI YGNERKIMQL HILNNPKDAA LAADAEFLKQ SLFNLLHEEA    50
SPLVVETVKL LSTSDDSAAL IEKVLPQLDE QQTHDLTLAC GLFAQILNIA 100
EDVHHERRRQ IHEEAGRGGA EGSLTETVRR LKAGKADGKS VQRQLDNTSV 150
TAVLTAHPTE VQRQTVLSFN RRIRALLPQR ERCTNADALA RLRREIDTIL 200
LGLWQTSETR RHKLSVNDEI NNGVSIFPMS FFEALPKLYR KMEHDFQTAY 250
PDVRVPNILK IGGWIGGDRD GNPFVSAETL RFAFRRHADA VFRFYRGELD 300
KLYRELPLSI RRVKVNDDVM ALAALSPDEE LARTEEPYRR AIAYIMARAM 350
GKARALGLGM GCKFGFLEPY ASAQEFLDDL KKLQRSLIDN GSRLLAEGRL 400
ADLIRSVSVF GFHMMPLDLR QHAGKHADVV TELFQHAGLE DYNSLNEEQK 450
QAVLLRELSH QRPLYSPFIT YSDHTRHELA IFNEARKIKD EFGEDAVTQS 500
IISNCEQPSD LLALALLLKE SGLLAVENGK PHSRINIVPL FETIEALENA 550
CPVMETMFRL DWYDALLESR GNIQEIMLGY SDSNKDGGYV TSSWCLYQAE 600
LGLVELFKKY DVRMRLFHGR GGSVGRGGGP SYQAILAQPA GSVAGQIRIT 650
EQGEVITAKY ADPGNAQRNL ETLVAATLEA SILPDKKDPD AKLMQALSDV 700
SFKYYRELIT HPDFIDYFLQ TSPIQEIATL NLGSRPASRK TLARIQDLRA 750
IPWVFSWMQN RLMLPAWYGF GSAVETLCEG SPETLAALRE HAQSNPFFQA 800
MLSNMEQVMA KTDITLAENY AGLSESPEKA AVIFGMIKEE YQRSRKALLD 850
LLQTEELLRD NRSLARSLAL RIPYLNALNG LQVAMLKRLR KEPDNPHALL 900
MVHLTINGVA QGLRNTG 917
Length:917
Mass (Da):103,265
Last modified:January 11, 2011 - v1
Checksum:i209AFEB38A242C9D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001561 Genomic DNA. Translation: ADO32481.1.
RefSeqiYP_005883612.1. NC_017505.1.

Genome annotation databases

EnsemblBacteriaiADO32481; ADO32481; NMBB_2367.
GeneIDi12399994.
KEGGinmp:NMBB_2367.
PATRICi43138228. VBINeiMen23504_2762.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001561 Genomic DNA. Translation: ADO32481.1 .
RefSeqi YP_005883612.1. NC_017505.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADO32481 ; ADO32481 ; NMBB_2367 .
GeneIDi 12399994.
KEGGi nmp:NMBB_2367.
PATRICi 43138228. VBINeiMen23504_2762.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci NMEN630588:GLHP-2046-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence."
    Joseph B., Schneiker-Bekel S., Schramm-Gluck A., Blom J., Claus H., Linke B., Schwarz R.F., Becker A., Goesmann A., Frosch M., Schoen C.
    J. Bacteriol. 192:5363-5377(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: alpha710.

Entry informationi

Entry nameiE3D3X1_NEIM7
AccessioniPrimary (citable) accession number: E3D3X1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: June 11, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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