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E3D3X1 (E3D3X1_NEIM7) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
Ordered Locus Names:NMBB_2367 EMBL ADO32481.1
OrganismNeisseria meningitidis serogroup B (strain alpha710) [Complete proteome] [HAMAP] EMBL ADO32481.1
Taxonomic identifier630588 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length917 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1571 By similarity HAMAP-Rule MF_00595
Active site5851 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
E3D3X1 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 209AFEB38A242C9D

FASTA917103,265
        10         20         30         40         50         60 
MRHLRYIYSI YGNERKIMQL HILNNPKDAA LAADAEFLKQ SLFNLLHEEA SPLVVETVKL 

        70         80         90        100        110        120 
LSTSDDSAAL IEKVLPQLDE QQTHDLTLAC GLFAQILNIA EDVHHERRRQ IHEEAGRGGA 

       130        140        150        160        170        180 
EGSLTETVRR LKAGKADGKS VQRQLDNTSV TAVLTAHPTE VQRQTVLSFN RRIRALLPQR 

       190        200        210        220        230        240 
ERCTNADALA RLRREIDTIL LGLWQTSETR RHKLSVNDEI NNGVSIFPMS FFEALPKLYR 

       250        260        270        280        290        300 
KMEHDFQTAY PDVRVPNILK IGGWIGGDRD GNPFVSAETL RFAFRRHADA VFRFYRGELD 

       310        320        330        340        350        360 
KLYRELPLSI RRVKVNDDVM ALAALSPDEE LARTEEPYRR AIAYIMARAM GKARALGLGM 

       370        380        390        400        410        420 
GCKFGFLEPY ASAQEFLDDL KKLQRSLIDN GSRLLAEGRL ADLIRSVSVF GFHMMPLDLR 

       430        440        450        460        470        480 
QHAGKHADVV TELFQHAGLE DYNSLNEEQK QAVLLRELSH QRPLYSPFIT YSDHTRHELA 

       490        500        510        520        530        540 
IFNEARKIKD EFGEDAVTQS IISNCEQPSD LLALALLLKE SGLLAVENGK PHSRINIVPL 

       550        560        570        580        590        600 
FETIEALENA CPVMETMFRL DWYDALLESR GNIQEIMLGY SDSNKDGGYV TSSWCLYQAE 

       610        620        630        640        650        660 
LGLVELFKKY DVRMRLFHGR GGSVGRGGGP SYQAILAQPA GSVAGQIRIT EQGEVITAKY 

       670        680        690        700        710        720 
ADPGNAQRNL ETLVAATLEA SILPDKKDPD AKLMQALSDV SFKYYRELIT HPDFIDYFLQ 

       730        740        750        760        770        780 
TSPIQEIATL NLGSRPASRK TLARIQDLRA IPWVFSWMQN RLMLPAWYGF GSAVETLCEG 

       790        800        810        820        830        840 
SPETLAALRE HAQSNPFFQA MLSNMEQVMA KTDITLAENY AGLSESPEKA AVIFGMIKEE 

       850        860        870        880        890        900 
YQRSRKALLD LLQTEELLRD NRSLARSLAL RIPYLNALNG LQVAMLKRLR KEPDNPHALL 

       910 
MVHLTINGVA QGLRNTG 

« Hide

References

[1]"Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence."
Joseph B., Schneiker-Bekel S., Schramm-Gluck A., Blom J., Claus H., Linke B., Schwarz R.F., Becker A., Goesmann A., Frosch M., Schoen C.
J. Bacteriol. 192:5363-5377(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: alpha710.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001561 Genomic DNA. Translation: ADO32481.1.
RefSeqYP_005883612.1. NC_017505.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO32481; ADO32481; NMBB_2367.
GeneID12399994.
KEGGnmp:NMBB_2367.
PATRIC43138228. VBINeiMen23504_2762.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Enzyme and pathway databases

BioCycNMEN630588:GLHP-2046-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3D3X1_NEIM7
AccessionPrimary (citable) accession number: E3D3X1
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: June 11, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)