SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E3D1J2

- E3D1J2_NEIM7

UniProt

E3D1J2 - E3D1J2_NEIM7

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene
NMBB_1888
Organism
Neisseria meningitidis serogroup B (strain alpha710)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei33 – 331Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei129 – 1291Substrate By similarityUniRule annotation
Active sitei250 – 2501Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei298 – 2981Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciNMEN630588:GLHP-1634-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:NMBB_1888Imported
OrganismiNeisseria meningitidis serogroup B (strain alpha710)Imported
Taxonomic identifieri630588 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000006929: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei33 – 331N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE3D1J2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3D1J2-1 [UniParc]FASTAAdd to Basket

« Hide

MRPLNVQIRL GNLRHNYRIL KEMHGGKLLA VVKADAYGHG AVRCAFALAD    50
LADGFAVATI DEGIRLRESG ITHPIVLLEG VFEASEYEAV EQYSLWPAVG 100
NQWQLEALLS RHWKKPVKVW LKMDSGMHRT GFFPHDYASA YAALKQSEYV 150
DSIVKFSHFS CADEPESGIT EIQMEAFDLG TEGLEGEESL ANSAAILNVP 200
EARRDWGRAG LALYGISPFG GSDDRLKPVM RLSTRIFGER VLQPHSPIGY 250
GATFYTSKST RVGLIACGYA DGYPRRAPSN SPVAVDGKLT RVIGRVSMDM 300
MTIELDASQE GLGHEVELWG DTVNINTVAE AAGTIPYELM CNIKRAKFTY 350
IE 352
Length:352
Mass (Da):38,802
Last modified:January 11, 2011 - v1
Checksum:iC0EEFE13486F2756
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001561 Genomic DNA. Translation: ADO32091.1.
RefSeqiYP_005883222.1. NC_017505.1.

Genome annotation databases

EnsemblBacteriaiADO32091; ADO32091; NMBB_1888.
GeneIDi12399575.
KEGGinmp:NMBB_1888.
PATRICi43137034. VBINeiMen23504_2178.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001561 Genomic DNA. Translation: ADO32091.1 .
RefSeqi YP_005883222.1. NC_017505.1.

3D structure databases

ProteinModelPortali E3D1J2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADO32091 ; ADO32091 ; NMBB_1888 .
GeneIDi 12399575.
KEGGi nmp:NMBB_1888.
PATRICi 43137034. VBINeiMen23504_2178.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci NMEN630588:GLHP-1634-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence."
    Joseph B., Schneiker-Bekel S., Schramm-Gluck A., Blom J., Claus H., Linke B., Schwarz R.F., Becker A., Goesmann A., Frosch M., Schoen C.
    J. Bacteriol. 192:5363-5377(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: alpha710.

Entry informationi

Entry nameiE3D1J2_NEIM7
AccessioniPrimary (citable) accession number: E3D1J2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi