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Protein
Submitted name:

Interferon induced with helicase C domain 1

Gene

IFIH1

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi910ZincPROSITE-ProRule annotation1
Metal bindingi913ZincPROSITE-ProRule annotation1
Metal bindingi965ZincPROSITE-ProRule annotation1
Metal bindingi968ZincPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-bindingPROSITE-ProRule annotation, ZincPROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-CFA-5689880 Ub-specific processing proteases

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon induced with helicase C domain 1Imported
Gene namesi
Name:IFIH1Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 36

Organism-specific databases

VGNCiVGNC:41876 IFIH1

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiE2RNK0

Expressioni

Gene expression databases

BgeeiENSCAFG00000010438

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000015359

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 177CARDInterPro annotationAdd BLAST67
Domaini317 – 510Helicase ATP-bindingInterPro annotationAdd BLAST194
Domaini703 – 885Helicase C-terminalInterPro annotationAdd BLAST183
Domaini896 – 1024RLR CTRInterPro annotationAdd BLAST129

Phylogenomic databases

eggNOGiKOG0354 Eukaryota
COG1111 LUCA
GeneTreeiENSGT00510000046789
InParanoidiE2RNK0
KOiK12647
OMAiYNNIMRR
OrthoDBiEOG091G01PQ
TreeFamiTF330258

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di2.170.150.30, 1 hit
InterProiView protein in InterPro
IPR001315 CARD
IPR031964 CARD_dom
IPR011029 DEATH-like_dom_sf
IPR006935 Helicase/UvrB_N
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038557 RLR_C_sf
IPR021673 RLR_CTR
PfamiView protein in Pfam
PF16739 CARD_2, 2 hits
PF00271 Helicase_C, 1 hit
PF04851 ResIII, 1 hit
PF11648 RIG-I_C-RD, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51789 RLR_CTR, 1 hit

Sequencei

Sequence statusi: Complete.

E2RNK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWSGRPSADQ SFRHLLSCFR ARVKTYIQVE PVLDYLNFLP EEVKEQIQRK
60 70 80 90 100
AANAGNLQAA ELLLSTLEKG AWPPGWTRQV LVALQSAGSV LASRYLNPEL
110 120 130 140 150
ADLPSPSAEN AHDQCLQLLH LLQPTLVDRL LVKDVLDKCV EKKLLTDEDR
160 170 180 190 200
DRISAAENNG NQSGVRELLK RIVQKENWFS LFLTVLNQTE NYALVQELTG
210 220 230 240 250
TTCFESKEET ENLSQEDGPE VKAAALLAMS QPSPEKEGWD MENNSLESSL
260 270 280 290 300
LDSSVVSESD TSLAEGSVSC LDESLGHNSN MGSDSGTMGS DSDEENVAER
310 320 330 340 350
ASPEPELHLR PYQMEVAQPA LEGKNIIICL PTGSGKTRVA VYIAKDHLDK
360 370 380 390 400
KKKASEPGKV IVLVNKVPLV EQLFREEFEP FLKKWYHTIG LSGDTQLKIS
410 420 430 440 450
FPEIVKTYDV IISTAQILEN SLLNSEKGED DGVQFSDFTL IIIDECHHTN
460 470 480 490 500
KEAVYNNIMR RYLKQKLKNN KLKKEYKPVI PLPQILGLTA SPGVRGAKRQ
510 520 530 540 550
AEAQQHILKI CANLDACTII TVKENINQLK GQMKEPCKKF AIADDTREDP
560 570 580 590 600
FKDKLLEIMN KIQSFCQMSP MSDFGTQPYE QWTIQMEKKA AREGNRKDRV
610 620 630 640 650
CAEHLRKYNE ALQINDTIRT IDAYNHLEAF YNDETEKKLA VQEGDSDESG
660 670 680 690 700
EDGDGDGDGD EAEDDEKRPL RLDRTDRFLM ELFWENKRML KKLAQNPKHE
710 720 730 740 750
NEKLIKLRNT IMEQFTRTEE PARGIIFTKT RQSAFALSQW ITENKKFAEV
760 770 780 790 800
GVKAHHLIGA GHSSEFKPMT QNEQKEVISK FRTGKINLLI ATTVAEEGLD
810 820 830 840 850
IKECNIVIRY GLVTNEIAMV QARGRARADE STYVLVAHSN SGVIEREIVN
860 870 880 890 900
DFREKMMYKA IDHVQNMNPE EYAHKILELQ MQSIMEKKMK IKRSAAKCYK
910 920 930 940 950
ENPSLINFLC KNCSVLACSG EDIHVIEKMH HVNMTPVFKE LYIVRENKAL
960 970 980 990 1000
RKKFIDYQTN GEIICKMCGQ AWGTMMVHKG LDLPCLKIKN FVVIFKNNTS
1010 1020
KKQYKKWVEL PIAFPDLDYS EYCLFSDED
Length:1,029
Mass (Da):116,935
Last modified:October 31, 2012 - v2
Checksum:i7818AEBC90E1BA6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03017717 Genomic DNA No translation available.
RefSeqiXP_545493.2, XM_545493.4

Genome annotation databases

EnsembliENSCAFT00000016597; ENSCAFP00000015359; ENSCAFG00000010438
GeneIDi488371
KEGGicfa:488371

Similar proteinsi

Entry informationi

Entry nameiE2RNK0_CANLF
AccessioniPrimary (citable) accession number: E2RNK0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: October 31, 2012
Last modified: March 28, 2018
This is version 55 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health