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Protein
Submitted name:

Uncharacterized protein

Gene

IFIH1

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CFA-5689880. Ub-specific processing proteases.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:IFIH1Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 36

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiE2RNK0.

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000015359.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 177CARDInterPro annotationAdd BLAST67
Domaini317 – 510Helicase ATP-bindingInterPro annotationAdd BLAST194
Domaini703 – 885Helicase C-terminalInterPro annotationAdd BLAST183

Phylogenomic databases

eggNOGiKOG0354. Eukaryota.
COG1111. LUCA.
GeneTreeiENSGT00510000046789.
InParanoidiE2RNK0.
KOiK12647.
OMAiEIICKCG.
OrthoDBiEOG091G01PQ.
TreeFamiTF330258.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001315. CARD.
IPR031964. CARD_dom.
IPR011029. DEATH-like_dom.
IPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR021673. RIG-I_C-RD.
[Graphical view]
PfamiPF16739. CARD_2. 2 hits.
PF00271. Helicase_C. 1 hit.
PF04851. ResIII. 1 hit.
PF11648. RIG-I_C-RD. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS50209. CARD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E2RNK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWSGRPSADQ SFRHLLSCFR ARVKTYIQVE PVLDYLNFLP EEVKEQIQRK
60 70 80 90 100
AANAGNLQAA ELLLSTLEKG AWPPGWTRQV LVALQSAGSV LASRYLNPEL
110 120 130 140 150
ADLPSPSAEN AHDQCLQLLH LLQPTLVDRL LVKDVLDKCV EKKLLTDEDR
160 170 180 190 200
DRISAAENNG NQSGVRELLK RIVQKENWFS LFLTVLNQTE NYALVQELTG
210 220 230 240 250
TTCFESKEET ENLSQEDGPE VKAAALLAMS QPSPEKEGWD MENNSLESSL
260 270 280 290 300
LDSSVVSESD TSLAEGSVSC LDESLGHNSN MGSDSGTMGS DSDEENVAER
310 320 330 340 350
ASPEPELHLR PYQMEVAQPA LEGKNIIICL PTGSGKTRVA VYIAKDHLDK
360 370 380 390 400
KKKASEPGKV IVLVNKVPLV EQLFREEFEP FLKKWYHTIG LSGDTQLKIS
410 420 430 440 450
FPEIVKTYDV IISTAQILEN SLLNSEKGED DGVQFSDFTL IIIDECHHTN
460 470 480 490 500
KEAVYNNIMR RYLKQKLKNN KLKKEYKPVI PLPQILGLTA SPGVRGAKRQ
510 520 530 540 550
AEAQQHILKI CANLDACTII TVKENINQLK GQMKEPCKKF AIADDTREDP
560 570 580 590 600
FKDKLLEIMN KIQSFCQMSP MSDFGTQPYE QWTIQMEKKA AREGNRKDRV
610 620 630 640 650
CAEHLRKYNE ALQINDTIRT IDAYNHLEAF YNDETEKKLA VQEGDSDESG
660 670 680 690 700
EDGDGDGDGD EAEDDEKRPL RLDRTDRFLM ELFWENKRML KKLAQNPKHE
710 720 730 740 750
NEKLIKLRNT IMEQFTRTEE PARGIIFTKT RQSAFALSQW ITENKKFAEV
760 770 780 790 800
GVKAHHLIGA GHSSEFKPMT QNEQKEVISK FRTGKINLLI ATTVAEEGLD
810 820 830 840 850
IKECNIVIRY GLVTNEIAMV QARGRARADE STYVLVAHSN SGVIEREIVN
860 870 880 890 900
DFREKMMYKA IDHVQNMNPE EYAHKILELQ MQSIMEKKMK IKRSAAKCYK
910 920 930 940 950
ENPSLINFLC KNCSVLACSG EDIHVIEKMH HVNMTPVFKE LYIVRENKAL
960 970 980 990 1000
RKKFIDYQTN GEIICKMCGQ AWGTMMVHKG LDLPCLKIKN FVVIFKNNTS
1010 1020
KKQYKKWVEL PIAFPDLDYS EYCLFSDED
Length:1,029
Mass (Da):116,935
Last modified:October 31, 2012 - v2
Checksum:i7818AEBC90E1BA6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03017717 Genomic DNA. No translation available.
RefSeqiXP_545493.2. XM_545493.4.

Genome annotation databases

EnsembliENSCAFT00000016597; ENSCAFP00000015359; ENSCAFG00000010438.
GeneIDi488371.
KEGGicfa:488371.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03017717 Genomic DNA. No translation available.
RefSeqiXP_545493.2. XM_545493.4.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000015359.

Proteomic databases

PaxDbiE2RNK0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000016597; ENSCAFP00000015359; ENSCAFG00000010438.
GeneIDi488371.
KEGGicfa:488371.

Organism-specific databases

CTDi64135.

Phylogenomic databases

eggNOGiKOG0354. Eukaryota.
COG1111. LUCA.
GeneTreeiENSGT00510000046789.
InParanoidiE2RNK0.
KOiK12647.
OMAiEIICKCG.
OrthoDBiEOG091G01PQ.
TreeFamiTF330258.

Enzyme and pathway databases

ReactomeiR-CFA-5689880. Ub-specific processing proteases.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001315. CARD.
IPR031964. CARD_dom.
IPR011029. DEATH-like_dom.
IPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR021673. RIG-I_C-RD.
[Graphical view]
PfamiPF16739. CARD_2. 2 hits.
PF00271. Helicase_C. 1 hit.
PF04851. ResIII. 1 hit.
PF11648. RIG-I_C-RD. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS50209. CARD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE2RNK0_CANLF
AccessioniPrimary (citable) accession number: E2RNK0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: October 31, 2012
Last modified: October 5, 2016
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.