ID   E2RI34_CANLF            Unreviewed;       148 AA.
AC   E2RI34;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   RecName: Full=Large ribosomal subunit protein uL15 {ECO:0000256|ARBA:ARBA00035200};
DE   AltName: Full=60S ribosomal protein L27a {ECO:0000256|ARBA:ARBA00035527};
GN   Name=RPL27A {ECO:0000313|Ensembl:ENSCAFP00845016523.1};
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615 {ECO:0000313|Ensembl:ENSCAFP00845016523.1, ECO:0000313|Proteomes:UP000805418};
RN   [1] {ECO:0000313|Ensembl:ENSCAFP00845016523.1}
RP   IDENTIFICATION.
RC   STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00845016523.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL15 family.
CC       {ECO:0000256|ARBA:ARBA00007320, ECO:0000256|RuleBase:RU003888}.
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DR   RefSeq; NP_001239154.1; NM_001252225.1.
DR   AlphaFoldDB; E2RI34; -.
DR   SMR; E2RI34; -.
DR   STRING; 9615.ENSCAFP00000010314; -.
DR   PaxDb; 9612-ENSCAFP00000040194; -.
DR   Ensembl; ENSCAFT00845021021.1; ENSCAFP00845016523.1; ENSCAFG00845011824.1.
DR   GeneID; 611398; -.
DR   KEGG; cfa:611398; -.
DR   CTD; 6157; -.
DR   VEuPathDB; HostDB:ENSCAFG00845011824; -.
DR   GeneTree; ENSGT00390000005534; -.
DR   OMA; WGRVGQH; -.
DR   OrthoDB; 5479329at2759; -.
DR   Reactome; R-CFA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-CFA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-CFA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-CFA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-CFA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-CFA-9629569; Protein hydroxylation.
DR   Reactome; R-CFA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-CFA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000805418; Chromosome 21.
DR   Bgee; ENSCAFG00000006936; Expressed in thyroid gland and 48 other cell types or tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 3.100.10.10; -; 1.
DR   Gene3D; 4.10.990.10; -; 1.
DR   HAMAP; MF_01341; Ribosomal_L15; 1.
DR   InterPro; IPR027386; Rbsml_uL15_N.
DR   InterPro; IPR030878; Ribosomal_uL15.
DR   InterPro; IPR021131; Ribosomal_uL15/eL18.
DR   InterPro; IPR036227; Ribosomal_uL15/eL18_sf.
DR   InterPro; IPR001196; Ribosomal_uL15_CS.
DR   PANTHER; PTHR11721; 60S RIBOSOMAL PROTEIN L27A; 1.
DR   PANTHER; PTHR11721:SF3; 60S RIBOSOMAL PROTEIN L27A; 1.
DR   Pfam; PF00828; Ribosomal_L27A; 1.
DR   SUPFAM; SSF52080; Ribosomal proteins L15p and L18e; 1.
DR   PROSITE; PS00475; RIBOSOMAL_L15; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000805418};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW   ECO:0000256|RuleBase:RU003888};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW   ECO:0000256|RuleBase:RU003888}.
FT   DOMAIN          28..145
FT                   /note="Large ribosomal subunit protein uL15/eL18"
FT                   /evidence="ECO:0000259|Pfam:PF00828"
SQ   SEQUENCE   148 AA;  16577 MW;  D6E11FBC33921056 CRC64;
     MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGMHH HRINFDKYHP GYFGKVGMRH
     YHLKRNQSFC PTVNLDKLWT LVSEQTRVNA AKNKTGAAPI IDVVRSGYYK VLGKGKLPKQ
     PVIVKAKFFS RRAEEKIKGV GGACVLVA
//