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Protein
Submitted name:

Microsomal glutathione S-transferase 1

Gene

MGST1

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-156590. Glutathione conjugation.
R-CFA-5423646. Aflatoxin activation and detoxification.
R-CFA-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Microsomal glutathione S-transferase 1Imported
Gene namesi
Name:MGST1Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 37HelicalSequence analysisAdd BLAST26
Transmembranei83 – 111HelicalSequence analysisAdd BLAST29
Transmembranei131 – 149HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE2RHK1.

Expressioni

Gene expression databases

BgeeiENSCAFG00000012619.

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000018590.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IXE1. Eukaryota.
ENOG4111VJG. LUCA.
GeneTreeiENSGT00390000011980.
InParanoidiE2RHK1.
KOiK00799.
OMAiFYRMTRK.
OrthoDBiEOG091G14I4.
TreeFamiTF105327.

Family and domain databases

Gene3Di1.20.120.550. 1 hit.
InterProiView protein in InterPro
IPR023352. MAPEG-like_dom.
IPR001129. Membr-assoc_MAPEG.
PfamiView protein in Pfam
PF01124. MAPEG. 1 hit.
SUPFAMiSSF161084. SSF161084. 1 hit.

Sequencei

Sequence statusi: Complete.

E2RHK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDLTELMEN EVFMAFASYT TIILSKMMFM STATAFFRLT RKVFANPEDC
60 70 80 90 100
ASFGKGENAK KYLRTDDRVE RVRRAHLNDL ENIVPFLGIG LLYSLSGPDL
110 120 130 140 150
STALLHFRLF VGARIYHTIA YLTPLPQPNR ALAFFIGYGV TFSMAYRLLK

SRLYL
Length:155
Mass (Da):17,725
Last modified:November 30, 2010 - v1
Checksum:i85FC0EFDBE6F4E6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03015235 Genomic DNA. No translation available.
RefSeqiXP_005637161.1. XM_005637104.2.
XP_005637162.1. XM_005637105.2.
XP_005637163.1. XM_005637106.2.

Genome annotation databases

EnsembliENSCAFT00000020041; ENSCAFP00000018590; ENSCAFG00000012619.
GeneIDi477683.
KEGGicfa:477683.

Similar proteinsi

Entry informationi

Entry nameiE2RHK1_CANLF
AccessioniPrimary (citable) accession number: E2RHK1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 25, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported