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Protein
Submitted name:

Uncharacterized protein

Gene

HYPK

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei224ATPPROSITE-ProRule annotation1
Binding sitei269ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi161 – 165ATPPROSITE-ProRule annotation5
Nucleotide bindingi325 – 329ATPPROSITE-ProRule annotation5
Nucleotide bindingi353 – 358ATPPROSITE-ProRule annotation6

GO - Molecular functioni

Keywordsi

Molecular functionKinasePROSITE-ProRule annotationSAAS annotation, Transferase
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CFA-71288. Creatine metabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:HYPKImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 30

PTM / Processingi

Proteomic databases

PaxDbiE2RAF1.

Expressioni

Gene expression databases

BgeeiENSCAFG00000013154.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 131Phosphagen kinase N-terminalInterPro annotationAdd BLAST87
Domaini158 – 400Phosphagen kinase C-terminalInterPro annotationAdd BLAST243

Sequence similaritiesi

Belongs to the ATP:guanido phosphotransferase family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3581. Eukaryota.
COG3869. LUCA.
GeneTreeiENSGT00550000074561.
KOiK00933.
TreeFamiTF314214.

Family and domain databases

Gene3Di1.10.135.10. 1 hit.
3.30.590.10. 1 hit.
InterProiView protein in InterPro
IPR000749. ATP-guanido_PTrfase.
IPR022415. ATP-guanido_PTrfase_AS.
IPR022414. ATP-guanido_PTrfase_cat.
IPR022413. ATP-guanido_PTrfase_N.
IPR036802. ATP-guanido_PTrfase_N_sf.
IPR014746. Gln_synth/guanido_kin_cat_dom.
PANTHERiPTHR11547. PTHR11547. 1 hit.
PfamiView protein in Pfam
PF00217. ATP-gua_Ptrans. 1 hit.
PF02807. ATP-gua_PtransN. 1 hit.
SUPFAMiSSF48034. SSF48034. 1 hit.
SSF55931. SSF55931. 1 hit.
PROSITEiView protein in PROSITE
PS00112. PHOSPHAGEN_KINASE. 1 hit.
PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
PS51509. PHOSPHAGEN_KINASE_N. 1 hit.

Sequencei

Sequence statusi: Complete.

E2RAF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGPFSRLLS ARPGLRLLAL AGAGSLAAGF LLRPEPVRAA SERRRLYPPS
60 70 80 90 100
AEYPDLRKHN NCMASHLTPA VYARLCDKTT PTGWTLDQCI QTGVDNPGHP
110 120 130 140 150
FIKTVGMVAG DEETYEVFAE LFDPVIQERH NGYDPRTMKH TTDLDASKIR
160 170 180 190 200
SGYFDERYVL SSRVRTGRSI RGLSLPPACT RAERREVERV VVDALSGLKG
210 220 230 240 250
DLAGRYYRLS EMTEAEQQQL IDDHFLFDKP VSPLLTAAGM ARDWPDARGI
260 270 280 290 300
WHNNEKSFLI WVNEEDHTRV ISMEKGGNMK RVFERFCRGL KEVERLIQER
310 320 330 340 350
GWEFMWNERL GYILTCPSNL GTGLRAGVHI KLPLLSKDSR FPKILENLRL
360 370 380 390 400
QKRGTGGVDT AATGSVFDIS NLDRLGKSEV ELVQLVIDGV NYLIDCERRL
410
ERGQDIRVPP PLVHNKH
Length:417
Mass (Da):47,076
Last modified:November 30, 2010 - v1
Checksum:i6A244A8B8778746C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03016092 Genomic DNA. No translation available.
RefSeqiXP_535451.1. XM_535451.5.

Genome annotation databases

EnsembliENSCAFT00000020895; ENSCAFP00000019401; ENSCAFG00000013154.
GeneIDi478277.
KEGGicfa:478277.

Similar proteinsi

Entry informationi

Entry nameiE2RAF1_CANLF
AccessioniPrimary (citable) accession number: E2RAF1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 25, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported