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Protein

Glutathione S-transferase

Gene

GSTM3

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-CFA-156590 Glutathione conjugation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferaseUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:GSTM3Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE2R5B9
PRIDEiE2R5B9

Expressioni

Gene expression databases

BgeeiENSCAFG00000019809

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000029332

Structurei

3D structure databases

ProteinModelPortaliE2R5B9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 93GST N-terminalInterPro annotationAdd BLAST88
Domaini95 – 213GST C-terminalInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the GST superfamily. Mu family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IN5J Eukaryota
ENOG4110YU0 LUCA
GeneTreeiENSGT00550000074559
InParanoidiE2R5B9
KOiK00799
OMAiDIMENQV
OrthoDBiEOG091G0K2E
TreeFamiTF353040

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR003081 GST_mu
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
PRINTSiPR01267 GSTRNSFRASEM
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

E2R5B9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSKSNMVL GYWDIRGLAH AIRMLLEFTD TCYEERRYTC GEAPDYDKSQ
60 70 80 90 100
WLDVKFKLDL DFPNLPYLMD GKNKITQSNA ILRYIARKHN MCGETEEERI
110 120 130 140 150
RVDIMENQIM DFRIQLVQLC YSPDLEKLKP RYLEQLPGQL KQFSLFLGKF
160 170 180 190 200
SWFAGEKLTF VDFLTYDVLD QNRMFEPKCL DEFPNLKAFM CRFEALEKIA
210 220
NYMQSDRFLK MPINNKMALW GNKRIC
Length:226
Mass (Da):26,935
Last modified:November 30, 2010 - v1
Checksum:i1AD9C8894F30A6FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004729 Genomic DNA No translation available.
RefSeqiXP_537037.1, XM_537037.4

Genome annotation databases

EnsembliENSCAFT00000031510; ENSCAFP00000029332; ENSCAFG00000019809
GeneIDi479911
KEGGicfa:479911

Similar proteinsi

Entry informationi

Entry nameiE2R5B9_CANLF
AccessioniPrimary (citable) accession number: E2R5B9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health