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Protein

Glutathione S-transferase

Gene

GSTM3

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-CFA-156590. Glutathione conjugation.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferaseUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:GSTM3Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE2R5B9.
PRIDEiE2R5B9.

Expressioni

Gene expression databases

BgeeiENSCAFG00000019809.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000029332.

Structurei

3D structure databases

ProteinModelPortaliE2R5B9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 93GST N-terminalInterPro annotationAdd BLAST88
Domaini95 – 213GST C-terminalInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the GST superfamily. Mu family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IN5J. Eukaryota.
ENOG4110YU0. LUCA.
GeneTreeiENSGT00550000074559.
InParanoidiE2R5B9.
KOiK00799.
OMAiDIMENQV.
OrthoDBiEOG091G0K2E.
TreeFamiTF353040.

Family and domain databases

InterProiView protein in InterPro
IPR010987. Glutathione-S-Trfase_C-like.
IPR036282. Glutathione-S-Trfase_C_sf.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR003081. GST_mu.
IPR036249. Thioredoxin-like_sf.
PfamiView protein in Pfam
PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
PRINTSiPR01267. GSTRNSFRASEM.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

E2R5B9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSKSNMVL GYWDIRGLAH AIRMLLEFTD TCYEERRYTC GEAPDYDKSQ
60 70 80 90 100
WLDVKFKLDL DFPNLPYLMD GKNKITQSNA ILRYIARKHN MCGETEEERI
110 120 130 140 150
RVDIMENQIM DFRIQLVQLC YSPDLEKLKP RYLEQLPGQL KQFSLFLGKF
160 170 180 190 200
SWFAGEKLTF VDFLTYDVLD QNRMFEPKCL DEFPNLKAFM CRFEALEKIA
210 220
NYMQSDRFLK MPINNKMALW GNKRIC
Length:226
Mass (Da):26,935
Last modified:November 30, 2010 - v1
Checksum:i1AD9C8894F30A6FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004729 Genomic DNA. No translation available.
RefSeqiXP_537037.1. XM_537037.4.

Genome annotation databases

EnsembliENSCAFT00000031510; ENSCAFP00000029332; ENSCAFG00000019809.
GeneIDi479911.
KEGGicfa:479911.

Similar proteinsi

Entry informationi

Entry nameiE2R5B9_CANLF
AccessioniPrimary (citable) accession number: E2R5B9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 25, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported