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Protein
Submitted name:

Galanin receptor 1

Gene

GALR1

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-CFA-375276 Peptide ligand-binding receptors
R-CFA-418594 G alpha (i) signalling events

Names & Taxonomyi

Protein namesi
Submitted name:
Galanin receptor 1Imported
Gene namesi
Name:GALR1Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 1

Organism-specific databases

VGNCiVGNC:41100 GALR1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 61HelicalSequence analysisAdd BLAST26
Transmembranei73 – 100HelicalSequence analysisAdd BLAST28
Transmembranei112 – 133HelicalSequence analysisAdd BLAST22
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Transmembranei201 – 226HelicalSequence analysisAdd BLAST26
Transmembranei247 – 264HelicalSequence analysisAdd BLAST18
Transmembranei284 – 308HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE2R155

Expressioni

Gene expression databases

BgeeiENSCAFG00000000015

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000000020

Structurei

3D structure databases

ProteinModelPortaliE2R155
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 305G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST254

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00860000133695
InParanoidiE2R155
KOiK04230
OMAiKQVFKCH
OrthoDBiEOG091G0ZDG
TreeFamiTF315737

Family and domain databases

CDDicd15098 7tmA_Gal1_R, 1 hit
InterProiView protein in InterPro
IPR003906 GAL1_rcpt
IPR000405 Galanin_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR01418 GALANIN1R
PR00663 GALANINR
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

E2R155-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELAAGNLSE GNASGPEPPA PEPRPLFGIG IGVENFITLV LFGLIFAFGV
60 70 80 90 100
LGNSLVITVL ARSKPGKPRS TTNLFILNLS IADLAYLLFC IPFQATVYAL
110 120 130 140 150
PTWVLGAFIC RFIHYFFTVS MLVSIFTLAA MSVDRYVAIV HSRRSSSLRV
160 170 180 190 200
SRNALLGVGF IWALSIAMAS PVAYHRRLFH WEVRNQTFCW EEWPNQGHKK
210 220 230 240 250
AYVVCTFVFG YLLPLLLICF CYAKVLNHLH KKLKNMSKKS EASKKKTAQT
260 270 280 290 300
VLVVVVVFGI SWLPHHVINL WAEFGVFPLT PASFLFRIAA HCLAYSNSSV
310 320 330 340 350
NPIIYAFLSE NFRKAYKQVF KCRTHSESPL NDTKENRSRV DTPPSTNCTH

V
Length:351
Mass (Da):39,339
Last modified:November 30, 2010 - v1
Checksum:i9F7A57AD2341FCCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03000040 Genomic DNA No translation available.
RefSeqiXP_541048.2, XM_541048.4

Genome annotation databases

EnsembliENSCAFT00000000022; ENSCAFP00000000020; ENSCAFG00000000015
GeneIDi483928
KEGGicfa:483928

Similar proteinsi

Entry informationi

Entry nameiE2R155_CANLF
AccessioniPrimary (citable) accession number: E2R155
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health