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Protein

60S ribosomal protein L15

Gene

RPL15

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CFA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CFA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L15
Gene namesi
Name:RPL15
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 23

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00004055882 – 20460S ribosomal protein L15Add BLAST203

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineBy similarity1
Modified residuei34PhosphoserineBy similarity1
Cross-linki83Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei97PhosphoserineBy similarity1
Modified residuei100PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Lipoprotein, Myristate, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiE2QXF3.
PRIDEiE2QXF3.

Expressioni

Gene expression databases

BgeeiENSCAFG00000005764.

Interactioni

Subunit structurei

Interacts with IFIT1 (via TPR repeats 1-4).By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000008630.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V5Zelectron microscopy8.70m1-204[»]
ProteinModelPortaliE2QXF3.
SMRiE2QXF3.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiE2QXF3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1678. Eukaryota.
COG1632. LUCA.
GeneTreeiENSGT00390000005092.
InParanoidiE2QXF3.
KOiK02877.
OMAiYWVAQDS.
OrthoDBiEOG091G0LFF.
TreeFamiTF300050.

Family and domain databases

Gene3Di3.40.1120.10. 1 hit.
InterProiView protein in InterPro
IPR024794. Rbsml_L15e_core_dom.
IPR000439. Ribosomal_L15e.
IPR020925. Ribosomal_L15e_CS.
IPR012678. Ribosomal_L23/L15e_core_dom.
PANTHERiPTHR11847. PTHR11847. 1 hit.
PfamiView protein in Pfam
PF00827. Ribosomal_L15e. 1 hit.
SMARTiView protein in SMART
SM01384. Ribosomal_L15e. 1 hit.
SUPFAMiSSF54189. SSF54189. 1 hit.
PROSITEiView protein in PROSITE
PS01194. RIBOSOMAL_L15E. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E2QXF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR
60 70 80 90 100
LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGVN QLKFARSLQS
110 120 130 140 150
VAEERAGRHC GALRVLNSYW VGEDSTYKFF EVILIDPFHK AIRRNPDTQW
160 170 180 190 200
ITKPVHKHRE MRGLTSAGRK SRGLGKGHKF HHTIGGSRRA AWRRRNTLQL

HRYR
Length:204
Mass (Da):24,146
Last modified:November 30, 2010 - v1
Checksum:iA6E3AD1A76C9506F
GO

Sequence databases

RefSeqiNP_001300707.1. NM_001313778.1.
XP_862876.1. XM_857783.3.

Genome annotation databases

EnsembliENSCAFT00000009299; ENSCAFP00000008630; ENSCAFG00000005764.
GeneIDi477046.
KEGGicfa:477046.

Similar proteinsi

Entry informationi

Entry nameiRL15_CANLF
AccessioniPrimary (citable) accession number: E2QXF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: November 30, 2010
Last modified: September 27, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families