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Protein
Submitted name:

Acyl-CoA dehydrogenase very long chain

Gene

ACADVL

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

ReactomeiR-CFA-77305. Beta oxidation of palmitoyl-CoA to myristoyl-CoA.

Names & Taxonomyi

Protein namesi
Submitted name:
Acyl-CoA dehydrogenase very long chainImported
Gene namesi
Name:ACADVLImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE2QXA3.
PRIDEiE2QXA3.

Expressioni

Gene expression databases

BgeeiENSCAFG00000016016.

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000023601.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini127 – 240Acyl-CoA_dh_NInterPro annotationAdd BLAST114
Domaini244 – 346Acyl-CoA_dh_MInterPro annotationAdd BLAST103
Domaini358 – 504Acyl-CoA_dh_1InterPro annotationAdd BLAST147

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0137. Eukaryota.
COG1960. LUCA.
GeneTreeiENSGT00760000119007.
InParanoidiE2QXA3.
OMAiNAFMGLR.
OrthoDBiEOG091G04BS.
TreeFamiTF105053.

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
InterProiView protein in InterPro
IPR006089. Acyl-CoA_DH_CS.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR036250. AcylCo_DH-like_C.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR037069. AcylCoA_DH/ox_N_sf.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
PfamiView protein in Pfam
PF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF02771. Acyl-CoA_dh_N. 1 hit.
SUPFAMiSSF47203. SSF47203. 1 hit.
SSF56645. SSF56645. 1 hit.
PROSITEiView protein in PROSITE
PS00072. ACYL_COA_DH_1. 1 hit.
PS00073. ACYL_COA_DH_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E2QXA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRWRPEAQPP RCIVDDESRP DQDRGDRSGW EMQAARMAPS VGRQLRRLGV
60 70 80 90 100
GSSRPSALLG QPLPGPACRP YASGAAQAVL EKSDSHSSEA PTREKQAKAE
110 120 130 140 150
SKSFAAGMFK GQLTTDQVFP YPSVLSEEQT QFLKELVGPV SRFFEEVNDP
160 170 180 190 200
AKNDTLEKVE ETTLQGLKEL GAFGLQVPSE LGGVGLCNTQ YARLVEIVGT
210 220 230 240 250
HDLGVGITLG AHQSIGFKGI LLFGTKAQKE KYLPKLASGE SIAAFCLTEP
260 270 280 290 300
SSGSDAASIR SSAVPSPCGK YYTLNGSKIW ISNGGLADVF TVFAKTPVTD
310 320 330 340 350
AATGAVKEKI TAFVVERSFG GVTHGPPEKK MGIKASNTAE VYFDSVRVPA
360 370 380 390 400
ENVLGEVGSG FKVAMHILNN GRFGMAAALA GTMRGIIAKA VDHAANRTQF
410 420 430 440 450
GEKIHNFGLI QEKLARMAML QYVTESMAYM VSANMDQGST DFQIEAAISK
460 470 480 490 500
IFGSEAAWKV TDECIQILGG MGFMKEPGVE RVLRDLRIFR IFEGTNDILR
510 520 530 540 550
LFVALQGCMD KGKELSGLGN ALKNPFGNAG LLLGEAGKQL RRRAGLGSGL
560 570 580 590 600
SLSGIIHQEL NRSGELTVQA LEQFATVVEA KLIKHKKGIV NEQFVLQRLA
610 620 630 640 650
DSAIDLYAMV VVLSSRASRS LSEGHPTAQH EKMLCDSWCI EAAARVRETM
660 670 680
AALQSDPQQQ ELFRNFKSIS KALVERGGMV TSNPLGF
Length:687
Mass (Da):74,041
Last modified:October 31, 2012 - v2
Checksum:iB759EFBADF852DDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03003605 Genomic DNA. No translation available.
AAEX03003606 Genomic DNA. No translation available.
AAEX03003607 Genomic DNA. No translation available.
AAEX03003608 Genomic DNA. No translation available.
AAEX03003609 Genomic DNA. No translation available.
AAEX03003610 Genomic DNA. No translation available.
AAEX03003611 Genomic DNA. No translation available.
AAEX03003612 Genomic DNA. No translation available.
AAEX03003613 Genomic DNA. No translation available.
AAEX03003614 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCAFT00000025417; ENSCAFP00000023601; ENSCAFG00000016016.

Similar proteinsi

Entry informationi

Entry nameiE2QXA3_CANLF
AccessioniPrimary (citable) accession number: E2QXA3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: October 31, 2012
Last modified: March 28, 2018
This is version 51 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported