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Protein

Palmitoyltransferase

Gene

CG1407

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG1407Imported, Dmel_CG1407Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033474. CG1407.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 37HelicalUniRule annotationAdd BLAST26
Transmembranei52 – 73HelicalUniRule annotationAdd BLAST22
Transmembranei173 – 193HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: FlyBase

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE2QCN5.

Expressioni

Gene expression databases

BgeeiFBgn0033474.
ExpressionAtlasiE2QCN5. differential.
GenevisibleiE2QCN5. DM.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0087522.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 201zf-DHHCInterPro annotationAdd BLAST74

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1315. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132259.
OrthoDBiEOG091G0AXR.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
IPR030293. ZDHHC15.
PANTHERiPTHR22883:SF162. PTHR22883:SF162. 1 hit.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

E2QCN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNDDHRRRK TPCGFCMAVF KWIPVLFITA VIAWSYYAYV VELCIRNSEN
60 70 80 90 100
RIGMIFMLLF YHLFLTLFMW SYWRTIMTSV GRIPDQWRIP DEEVSRLFRA
110 120 130 140 150
DSPDTQKRIL NNFARDLPVT NRTMNGSVRF CEKCKIIKPD RAHHCSVCSC
160 170 180 190 200
CVLKMDHHCP WVNNCVNFYN YKYFVLFLGY ALVYCLYVAF TSLHDFVEFW
210 220
KVGAVSFRFV STLATTLNAR CMRRPVS
Length:227
Mass (Da):26,868
Last modified:November 30, 2010 - v1
Checksum:iBA3D1FD8D6D3A690
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAM71051.2.
RefSeqiNP_724869.2. NM_165729.3.
UniGeneiDm.3930.

Genome annotation databases

EnsemblMetazoaiFBtr0300719; FBpp0289943; FBgn0033474.
GeneIDi36043.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAM71051.2.
RefSeqiNP_724869.2. NM_165729.3.
UniGeneiDm.3930.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0087522.

Proteomic databases

PaxDbiE2QCN5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0300719; FBpp0289943; FBgn0033474.
GeneIDi36043.

Organism-specific databases

FlyBaseiFBgn0033474. CG1407.

Phylogenomic databases

eggNOGiKOG1315. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132259.
OrthoDBiEOG091G0AXR.

Miscellaneous databases

GenomeRNAii36043.

Gene expression databases

BgeeiFBgn0033474.
ExpressionAtlasiE2QCN5. differential.
GenevisibleiE2QCN5. DM.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
IPR030293. ZDHHC15.
PANTHERiPTHR22883:SF162. PTHR22883:SF162. 1 hit.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE2QCN5_DROME
AccessioniPrimary (citable) accession number: E2QCN5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: April 12, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.