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Protein

Serine/threonine-protein phosphatase

Gene

Ppp3cc

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • brain development Source: RGD

Keywordsi

Molecular functionHydrolaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-111447. Activation of BAD and translocation to mitochondria.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:Ppp3ccImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi621616. Ppp3cc.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000009745.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 148SER_THR_PHOSPHATASEInterPro annotation6

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0375. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000063087.
InParanoidiF1M7P9.
OMAiFSLQHKI.
OrthoDBiEOG091G094R.
TreeFamiTF105557.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiView protein in InterPro
IPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
PfamiView protein in Pfam
PF00149. Metallophos. 1 hit.
PRINTSiPR00114. STPHPHTASE.
SMARTiView protein in SMART
SM00156. PP2Ac. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiView protein in PROSITE
PS00125. SER_THR_PHOSPHATASE. 1 hit.

Sequencei

Sequence statusi: Complete.

E2CWF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRRPQFST TERVIKAVPF PPTRRLTLKE VFENGKPKMD VLKNHLVKEG
60 70 80 90 100
RVEEDVALKI INDGAAILKQ EKTMLEVEAP ITVCGDVHGQ FFDLMKLFEV
110 120 130 140 150
GGSPSNTRYL FLGDYVDRGY FSIECVLYLW SLKINHPKTL FLLRGNHECR
160 170 180 190 200
HLTEYFTFKQ ECRIKYSELV YEACMHTFDC LPLAALLNQQ FLCVHGGMSP
210 220 230 240 250
EITCLDDIRK LDRFAEPPAF GPVCDLLWSD PLEDYGSEKT LEHYTHNTVR
260 270 280 290 300
GCSYFFSYPA VCEFLQNNSL LSIIRAHEAQ DAGYRMYRKN QATGFPSLIT
310 320 330 340 350
IFSAPNYLDV YNNKAAVLKY ENNVMNIRQF NCSPHPYWLP NFMDVFTWSL
360 370 380 390 400
PFVGEKVTEM LVNILNICSD EEMSLVEEED HYISSCPKGA TSVRKEVIRN
410 420 430 440 450
KIRAIGKMAR VFTVLREESE NVLILKGLTP TGTLPLGVLS GGKQTIETAK
460 470 480 490 500
LQAAEEREAI RGFTIAHRIR SFEEARGLDR INERMPPRKE ASYHHDAGKT
510
HPHPSKRSDH GKKAL
Length:515
Mass (Da):58,833
Last modified:November 30, 2010 - v1
Checksum:i51F7313171DA9059
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126842 Genomic DNA. No translation available.
GQ376198 mRNA. Translation: ADJ67995.1.
RefSeqiXP_008769035.1. XM_008770813.2.
UniGeneiRn.22079.

Genome annotation databases

EnsembliENSRNOT00000012993; ENSRNOP00000012993; ENSRNOG00000009745.
GeneIDi171378.

Similar proteinsi

Entry informationi

Entry nameiE2CWF0_RAT
AccessioniPrimary (citable) accession number: E2CWF0
Secondary accession number(s): F1M7P9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: August 30, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported