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Protein

PBAN-type neuropeptides

Gene

EAG_02707

Organism
Camponotus floridanus (Florida carpenter ant)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Pyrokinins mediate visceral muscle contractile activity (myotropic activity).By similarity

Miscellaneous

The structural similarity of PK1 and PK2 to CAPA-PK might compensate for the apparent absence of CAPA-PK in ants.1 Publication

GO - Biological processi

Keywordsi

Molecular functionNeuropeptide

Names & Taxonomyi

Protein namesi
Recommended name:
PBAN-type neuropeptidesImported
Cleaved into the following 4 chains:
Pyrokinin 11 Publication
Short name:
Pk 11 Publication
Pyrokinin 21 Publication
Short name:
Pk 21 Publication
Pyrokinin 31 Publication
Short name:
Pk 31 Publication
Pyrokinin 41 Publication
Short name:
Pk 41 Publication
Gene namesi
ORF Names:EAG_02707Imported
OrganismiCamponotus floridanus (Florida carpenter ant)Imported
Taxonomic identifieri104421 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataVespoideaFormicidaeFormicinaeCamponotus
Proteomesi
  • UP000000311 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
PropeptideiPRO_000043424324 – 541 PublicationAdd BLAST31
PeptideiPRO_000043424456 – 74Pyrokinin 11 PublicationAdd BLAST19
PropeptideiPRO_000043424578 – 1131 PublicationAdd BLAST36
PeptideiPRO_0000434246116 – 124Pyrokinin 21 Publication9
PeptideiPRO_0000434247127 – 154Pyrokinin 31 PublicationAdd BLAST28
PeptideiPRO_0000434248158 – 166Pyrokinin 41 Publication9
PropeptideiPRO_0000434249169 – 1771 Publication9

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei74Leucine amide1 Publication1
Modified residuei124Leucine amide1 Publication1
Modified residuei154Leucine amide1 Publication1
Modified residuei166Leucine amide1 Publication1

Keywords - PTMi

Amidation, Cleavage on pair of basic residues

Expressioni

Tissue specificityi

Pyrokinins (PK) 1 to 4 are expressed in the retrocerebral complex. PK 1 is expressed in central brain, anntennal lobes and abominal ganglia. PK 2 is expressed in optical lobes and in gnathal, thoracic and abdominal ganglia. PK 3 is expressed in optical lobes and in thoracic and abdominal ganglia (at protein level).1 Publication

Family & Domainsi

Sequence similaritiesi

Belongs to the pyrokinin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiE2AFK9.
OMAiITSGMWF.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E2AFK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVTGNPVCA IALLLCLVFR ASGEYELEMS SGGSNDGRSP SNDFGSCTDG
60 70 80 90 100
KCTKRTTTTQ ESGISSGMWF GPRLGKRHKS NEKQQINPEI EMLVNALDQP
110 120 130 140 150
GMRWTVITIP ANEKRQPTQF TPRLGRGSEE KFIYSDATDR NEIDEDDPLF
160 170
TPRLGRRVPW IPSPRLGRQS RSVSRKI
Length:177
Mass (Da):19,760
Last modified:November 30, 2010 - v1
Checksum:iEE2EC6F9D920109F
GO

Mass spectrometryi

Molecular mass is 2069.98 Da from positions 56 - 74. Determined by ESI. Pyrokinin 1.1 Publication
Molecular mass is 1069.57 Da from positions 116 - 124. Determined by ESI. Pyrokinin 2.1 Publication
Molecular mass is 3275.55 Da from positions 127 - 154. Determined by ESI. Pyrokinin 3.1 Publication
Molecular mass is 1065.64 Da from positions 158 - 166. Determined by ESI. Pyrokinin 4.1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL439118 Genomic DNA. Translation: EFN67760.1.
RefSeqiXP_011257226.1. XM_011258924.2.

Genome annotation databases

GeneIDi105251860.
KEGGicfo:105251860.

Similar proteinsi

Entry informationi

Entry nameiPPK_CAMFO
AccessioniPrimary (citable) accession number: E2AFK9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2015
Last sequence update: November 30, 2010
Last modified: June 7, 2017
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families