ID   E1ZFI5_CHLVA            Unreviewed;       529 AA.
AC   E1ZFI5;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE            EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN   ORFNames=CHLNCDRAFT_57929 {ECO:0000313|EMBL:EFN55138.1};
OS   Chlorella variabilis (Green alga).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC   Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX   NCBI_TaxID=554065 {ECO:0000313|Proteomes:UP000008141};
RN   [1] {ECO:0000313|EMBL:EFN55138.1, ECO:0000313|Proteomes:UP000008141}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NC64A {ECO:0000313|EMBL:EFN55138.1,
RC   ECO:0000313|Proteomes:UP000008141};
RX   PubMed=20852019; DOI=10.1105/tpc.110.076406;
RA   Blanc G., Duncan G., Agarkova I., Borodovsky M., Gurnon J., Kuo A.,
RA   Lindquist E., Lucas S., Pangilinan J., Polle J., Salamov A., Terry A.,
RA   Yamada T., Dunigan D.D., Grigoriev I.V., Claverie J.M., Van Etten J.L.;
RT   "The Chlorella variabilis NC64A genome reveals adaptation to
RT   photosymbiosis, coevolution with viruses, and cryptic sex.";
RL   Plant Cell 22:2943-2955(2010).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- PATHWAY: Amino-acid degradation; L-alanine degradation via transaminase
CC       pathway; pyruvate from L-alanine: step 1/1.
CC       {ECO:0000256|ARBA:ARBA00025708}.
CC   -!- PATHWAY: Photosynthesis; C4 acid pathway.
CC       {ECO:0000256|ARBA:ARBA00025709}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. Alanine aminotransferase subfamily.
CC       {ECO:0000256|ARBA:ARBA00025785}.
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DR   EMBL; GL433845; EFN55138.1; -; Genomic_DNA.
DR   RefSeq; XP_005847240.1; XM_005847178.1.
DR   AlphaFoldDB; E1ZFI5; -.
DR   STRING; 554065.E1ZFI5; -.
DR   GeneID; 17354552; -.
DR   KEGG; cvr:CHLNCDRAFT_57929; -.
DR   eggNOG; KOG0258; Eukaryota.
DR   InParanoid; E1ZFI5; -.
DR   OMA; IGDPNLF; -.
DR   OrthoDB; 5472891at2759; -.
DR   UniPathway; UPA00322; -.
DR   UniPathway; UPA00528; UER00586.
DR   Proteomes; UP000008141; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 1.10.287.1970; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR045088; ALAT1/2-like.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11751; ALANINE AMINOTRANSFERASE; 1.
DR   PANTHER; PTHR11751:SF373; ALANINE AMINOTRANSFERASE-RELATED; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008141};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          153..514
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   529 AA;  57512 MW;  0ED02AC4D4126435 CRC64;
     MCMLCVARKG SALSSGARQL LSNWQCPVKA SGSQLAQGRL FSSLPEPAHE PTRPNEVEGK
     VAHPSLLNED LLKAEYAVRG ELYNKAMELQ KQGRELIFTN VGNPQQLGQQ PITFNRMVTS
     LVAAPFLMGH PSAPSMFPAD VLERAKKING MFGGALGAYT DSRGNAGVRQ EVADFIKQRD
     GYPSNPDNIF LTDGASVAVR LLLNALIRDS SDAILVPIPQ YPLYSASIQL YGGTLLPYNL
     KEQTGWSMDF NEISRSVHDA RNHGTNVRAM VFINPGNPTG QCLTEDNLRD LVRFAAKEKV
     VLMADEVYQP NIYQDEKPFV SAKKVLGDLG KPISDSVELA SFHTVSKGVL GECGLRGGYV
     ELTNFHPGTV DELYKAVSIN LSPNTTGQVA MSLMVNPPKP GDESYAQWKA EHDEGLASLR
     RRAHAMTDGF NALDGVTCTF TEGAMYSFPR LHLPPKAIAA AAAAGKPADT FYCLQLLEAT
     GIVTVPGSGF GQEEGTFHLR TTILPPEAKI GEFVKLFQDF HKAFMAKYA
//