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E1XSL3

- E1XSL3_STRZI

UniProt

E1XSL3 - E1XSL3_STRZI

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Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

nanA

Organism
Streptococcus pneumoniae serotype 1 (strain INV104)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSPNE869269:GLL8-1449-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported
Gene namesi
Name:nanAImported
Ordered Locus Names:INV104_14420Imported
OrganismiStreptococcus pneumoniae serotype 1 (strain INV104)Imported
Taxonomic identifieri869269 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008966: Chromosome

Subcellular locationi

Secretedcell wall SAAS annotation; Peptidoglycan-anchor SAAS annotation

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliE1XSL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01186.
OMAiGGPKREN.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1XSL3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNRSVQERKC RYSIRKLSVG AVSMIVGAVV FGTSPVLAQE GASEQPLANE
60 70 80 90 100
TQLSGESSTL TDTEKSQPSS ETELSGNKQE QERKDKQEEK IPRDYYARDL
110 120 130 140 150
ENVETVIEKE DVETNASNGQ RVDLSSELDK LKKLENATVH MEFKPDAKAP
160 170 180 190 200
AFYNLFSVSS ATKKDEYFTM AVYNNTATLE GRGSDGKQFY NNYNDAPLKV
210 220 230 240 250
KPGQWNSVTF TVEKPTAELP NGRVRLYVNG VLSRTSLKSG NFIKDMPDVT
260 270 280 290 300
HVQIGATKRA NNTVWGSNLQ IRNLTVYNRA LTPEEVQKRS QLFKRSDLEK
310 320 330 340 350
KLPEGAALTE KTDIFESGRN GKPNKDGIKS YRIPALLKTD KGTLIAGADE
360 370 380 390 400
RRLHSSDWGD IGMVIRRSED NGKTWGNRVT ITNLRDNPKA SDPSIGSPVN
410 420 430 440 450
IDMVLVQDPE TKRIFSIYDM FPEGKGIFGM SSQKEEAYKK IDGKTYQILY
460 470 480 490 500
REGEKGAYTI RENGTVYTPD GKATDYRVVV DPVKPAYSDK GDLYKGNQLL
510 520 530 540 550
GNIYFTTNKT SPFRIAKDSY LWMSYSDDDG KTWSAPQDIT PMVKADWMKF
560 570 580 590 600
LGVGPGTGIV LRNGPHKGRI LIPVYTTNNV SHLNGSQSSR VIYSDDHGKT
610 620 630 640 650
WHAGEAVNDN RQVDGQKIHS STMNNRRAQN TESTVVQLNN GDVKLFMRGL
660 670 680 690 700
TGDLQVATSK DGGVTWEKDI KRYPQVKDVY VQMSAIHTMH NGKEYIILSN
710 720 730 740 750
AGGPNRENGM VHLARVEENG ELTWLKHNPI QKGEFAYNSL QELGNGEYGI
760 770 780 790 800
LYEHTEKGQN AYTLSFRKFN WEFLSKDLIS PTEAKVKRTR EMGKGEMGKG
810 820 830 840 850
VIGLEFDSEV LVNKAPTLQL ANGKTATFLT QYDSKTLLFA VDKEDIGQEI
860 870 880 890 900
IGIAKGSIES MHNLPVNLAG ARVPGGVNGS KAAVHEVPEF TGGVNGTEPA
910 920 930 940 950
VHEIAEYKGS DSLVTLTTKE DYTYKAPLAQ QALPETGNKE SDLLASLGLT
960
AFFLGLFTLG KKREQ
Length:965
Mass (Da):107,085
Last modified:November 30, 2010 - v1
Checksum:i5D2C79EF2B1758EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312030 Genomic DNA. Translation: CBW37123.1.
RefSeqiYP_006063062.1. NC_017591.1.

Genome annotation databases

EnsemblBacteriaiCBW37123; CBW37123; INV104_14420.
GeneIDi12889714.
KEGGisni:INV104_14420.
PATRICi43222903. VBIStrPne166045_1804.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312030 Genomic DNA. Translation: CBW37123.1 .
RefSeqi YP_006063062.1. NC_017591.1.

3D structure databases

ProteinModelPortali E1XSL3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBW37123 ; CBW37123 ; INV104_14420 .
GeneIDi 12889714.
KEGGi sni:INV104_14420.
PATRICi 43222903. VBIStrPne166045_1804.

Phylogenomic databases

KOi K01186.
OMAi GGPKREN.

Enzyme and pathway databases

BioCyci SPNE869269:GLL8-1449-MONOMER.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SMARTi SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome."
    Hiller N.L., Janto B., Hogg J.S., Boissy R., Yu S., Powell E., Keefe R., Ehrlich N.E., Shen K., Hayes J., Barbadora K., Klimke W., Dernovoy D., Tatusova T., Parkhill J., Bentley S.D., Post J.C., Ehrlich G.D., Hu F.Z.
    J. Bacteriol. 189:8186-8195(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: INV104Imported.

Entry informationi

Entry nameiE1XSL3_STRZI
AccessioniPrimary (citable) accession number: E1XSL3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: November 26, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3