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E1XSK8

- E1XSK8_STRZI

UniProt

E1XSK8 - E1XSK8_STRZI

Protein
Submitted name:

Sialidase B (Neuraminidase B)

Gene

nanB

Organism
Streptococcus pneumoniae serotype 1 (strain INV104)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (30 Nov 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
    2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
    3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseImported, Hydrolase

    Enzyme and pathway databases

    BioCyciSPNE869269:GLL8-1444-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sialidase B (Neuraminidase B)Imported (EC:3.2.1.18Imported)
    Gene namesi
    Name:nanBImported
    Ordered Locus Names:INV104_14370Imported
    OrganismiStreptococcus pneumoniae serotype 1 (strain INV104)Imported
    Taxonomic identifieri869269 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000008966: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE1XSK8.
    SMRiE1XSK8. Positions 39-696.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK01186.
    OMAiWRYHYDI.

    Family and domain databases

    Gene3Di2.120.10.10. 2 hits.
    2.40.220.10. 1 hit.
    2.60.120.200. 1 hit.
    InterProiIPR002860. BNR_rpt.
    IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR011040. Sialidases.
    IPR023364. Trans_sialidase_dom3.
    [Graphical view]
    PfamiPF02012. BNR. 1 hit.
    PF02973. Sialidase. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    E1XSK8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKRGLYSKL GISVVGISLL MGVPTLIHAN ELNYGQLSIS PIFQGGSYQL    50
    NNKSIDISSL LLDKLSGESQ TVVMKFKADK PNSLQALFGL SNSKAGFKNN 100
    YFSIFMRDSG EIGVEIRDAQ KGINYLFSRP ASLWGKHKGQ AVENTLVFVS 150
    DSKDKTYTMY VNGIEVFSET VDTFLPISNI NGIDKATLGA VNREGKEHYL 200
    AKGSIDEISL FNKAISDQEV STIPLSNPFQ LIFQSGDSTQ ANYFRIPTLY 250
    TLSSGRVLSS IDARYGGTHD SKSKINIATS YSDDNGKTWS EPIFAMKFND 300
    YEEQLVYWPR DNKLKNSQIS GSASFIDSSI VEDKKSGKTI LLADVMPAGI 350
    GNNNANKADS GFKEINGHYY LKLKKNGDND FRYTVRENGV VYNETTNKPT 400
    NYTINDKYEV LEGGKSLTVE QYSVDFDSGS LRERHNGKQV PMNVFYKDSL 450
    FKVTPTNYIA MTTSQNRGES WEQFKLLPPF LGEKHNGTYL CPGQGLALKS 500
    SNRLIFATYT SGELTYLISD DSGQTWKKSS ASIPFKNATA EAQMVELRDG 550
    VIRTFFRTTT GKIAYMTSRD SGETWSKVSY IDGIQQTSYG TQVSAIKYSQ 600
    LIDGKEAVIL STPNSRSGRK GGQLVVGLVN KEDDSIDWKY HYDIDLPSYG 650
    YAYSAITELP NHHIGVLFEK YDSWSRNELH LSNVVQYIDL EINDLTK 697
    Length:697
    Mass (Da):77,695
    Last modified:November 30, 2010 - v1
    Checksum:iA0D9F9AFDE46AFD7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312030 Genomic DNA. Translation: CBW37118.1.
    RefSeqiYP_006063057.1. NC_017591.1.

    Genome annotation databases

    EnsemblBacteriaiCBW37118; CBW37118; INV104_14370.
    GeneIDi12889709.
    KEGGisni:INV104_14370.
    PATRICi43222891. VBIStrPne166045_1797.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312030 Genomic DNA. Translation: CBW37118.1 .
    RefSeqi YP_006063057.1. NC_017591.1.

    3D structure databases

    ProteinModelPortali E1XSK8.
    SMRi E1XSK8. Positions 39-696.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBW37118 ; CBW37118 ; INV104_14370 .
    GeneIDi 12889709.
    KEGGi sni:INV104_14370.
    PATRICi 43222891. VBIStrPne166045_1797.

    Phylogenomic databases

    KOi K01186.
    OMAi WRYHYDI.

    Enzyme and pathway databases

    BioCyci SPNE869269:GLL8-1444-MONOMER.

    Family and domain databases

    Gene3Di 2.120.10.10. 2 hits.
    2.40.220.10. 1 hit.
    2.60.120.200. 1 hit.
    InterProi IPR002860. BNR_rpt.
    IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR011040. Sialidases.
    IPR023364. Trans_sialidase_dom3.
    [Graphical view ]
    Pfami PF02012. BNR. 1 hit.
    PF02973. Sialidase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome."
      Hiller N.L., Janto B., Hogg J.S., Boissy R., Yu S., Powell E., Keefe R., Ehrlich N.E., Shen K., Hayes J., Barbadora K., Klimke W., Dernovoy D., Tatusova T., Parkhill J., Bentley S.D., Post J.C., Ehrlich G.D., Hu F.Z.
      J. Bacteriol. 189:8186-8195(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: INV104Imported.

    Entry informationi

    Entry nameiE1XSK8_STRZI
    AccessioniPrimary (citable) accession number: E1XSK8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3