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E1XSK8

- E1XSK8_STRZI

UniProt

E1XSK8 - E1XSK8_STRZI

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Protein
Submitted name: Sialidase B (Neuraminidase B)
Gene
nanB, INV104_14370
Organism
Streptococcus pneumoniae serotype 1 (strain INV104)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciSPNE869269:GLL8-1444-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase B (Neuraminidase B)Imported (EC:3.2.1.18Imported)
Gene namesi
Name:nanBImported
Ordered Locus Names:INV104_14370Imported
OrganismiStreptococcus pneumoniae serotype 1 (strain INV104)Imported
Taxonomic identifieri869269 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008966: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE1XSK8.
SMRiE1XSK8. Positions 39-696.

Family & Domainsi

Phylogenomic databases

KOiK01186.
OMAiWRYHYDI.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR002860. BNR_rpt.
IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view]
PfamiPF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.

Sequencei

Sequence statusi: Complete.

E1XSK8-1 [UniParc]FASTAAdd to Basket

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MNKRGLYSKL GISVVGISLL MGVPTLIHAN ELNYGQLSIS PIFQGGSYQL    50
NNKSIDISSL LLDKLSGESQ TVVMKFKADK PNSLQALFGL SNSKAGFKNN 100
YFSIFMRDSG EIGVEIRDAQ KGINYLFSRP ASLWGKHKGQ AVENTLVFVS 150
DSKDKTYTMY VNGIEVFSET VDTFLPISNI NGIDKATLGA VNREGKEHYL 200
AKGSIDEISL FNKAISDQEV STIPLSNPFQ LIFQSGDSTQ ANYFRIPTLY 250
TLSSGRVLSS IDARYGGTHD SKSKINIATS YSDDNGKTWS EPIFAMKFND 300
YEEQLVYWPR DNKLKNSQIS GSASFIDSSI VEDKKSGKTI LLADVMPAGI 350
GNNNANKADS GFKEINGHYY LKLKKNGDND FRYTVRENGV VYNETTNKPT 400
NYTINDKYEV LEGGKSLTVE QYSVDFDSGS LRERHNGKQV PMNVFYKDSL 450
FKVTPTNYIA MTTSQNRGES WEQFKLLPPF LGEKHNGTYL CPGQGLALKS 500
SNRLIFATYT SGELTYLISD DSGQTWKKSS ASIPFKNATA EAQMVELRDG 550
VIRTFFRTTT GKIAYMTSRD SGETWSKVSY IDGIQQTSYG TQVSAIKYSQ 600
LIDGKEAVIL STPNSRSGRK GGQLVVGLVN KEDDSIDWKY HYDIDLPSYG 650
YAYSAITELP NHHIGVLFEK YDSWSRNELH LSNVVQYIDL EINDLTK 697
Length:697
Mass (Da):77,695
Last modified:November 30, 2010 - v1
Checksum:iA0D9F9AFDE46AFD7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312030 Genomic DNA. Translation: CBW37118.1.
RefSeqiYP_006063057.1. NC_017591.1.

Genome annotation databases

EnsemblBacteriaiCBW37118; CBW37118; INV104_14370.
GeneIDi12889709.
KEGGisni:INV104_14370.
PATRICi43222891. VBIStrPne166045_1797.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312030 Genomic DNA. Translation: CBW37118.1 .
RefSeqi YP_006063057.1. NC_017591.1.

3D structure databases

ProteinModelPortali E1XSK8.
SMRi E1XSK8. Positions 39-696.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBW37118 ; CBW37118 ; INV104_14370 .
GeneIDi 12889709.
KEGGi sni:INV104_14370.
PATRICi 43222891. VBIStrPne166045_1797.

Phylogenomic databases

KOi K01186.
OMAi WRYHYDI.

Enzyme and pathway databases

BioCyci SPNE869269:GLL8-1444-MONOMER.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProi IPR002860. BNR_rpt.
IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view ]
Pfami PF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome."
    Hiller N.L., Janto B., Hogg J.S., Boissy R., Yu S., Powell E., Keefe R., Ehrlich N.E., Shen K., Hayes J., Barbadora K., Klimke W., Dernovoy D., Tatusova T., Parkhill J., Bentley S.D., Post J.C., Ehrlich G.D., Hu F.Z.
    J. Bacteriol. 189:8186-8195(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: INV104.

Entry informationi

Entry nameiE1XSK8_STRZI
AccessioniPrimary (citable) accession number: E1XSK8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: May 14, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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