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E1X8C5 (E1X8C5_HAEI1) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
Ordered Locus Names:HIB_18150 EMBL CBW30000.1
OrganismHaemophilus influenzae (strain 10810) [Complete proteome] [HAMAP] EMBL CBW30000.1
Taxonomic identifier862964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length866 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595 SAAS SAAS022805

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS021135

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1251 By similarity HAMAP-Rule MF_00595
Active site5321 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
E1X8C5 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: AC260237A99A07CF

FASTA86698,517
        10         20         30         40         50         60 
MLGRFLGETI NDAQGEDILE LIENIRKLSR NSRAGDDKAR QALLDTLGSI SNENIIPVAR 

        70         80         90        100        110        120 
AFSQFLNLTN IAEQYQTISR EHSLAQSSSQ SLSELFKRLK EQNASVEEVH KTVEKLLIEL 

       130        140        150        160        170        180 
VLTAHPTETT RRSLIHKHIE INKCLSKLEH HDLTEKERNI IERLLLRLIA EAWHTNEIRT 

       190        200        210        220        230        240 
VRPTPFDEAK WGFAMLENSL WQAVPEFLRQ LNETAREFLG YDLPVGLKPV RISSWMGGDR 

       250        260        270        280        290        300 
DGNPFVTAQI TKKVLYFARW KAADLFLQDI SKLADELSMM KCSDEFRDKY GEQLEPYRFV 

       310        320        330        340        350        360 
VKNLRNQLTA TLAYFDDHLS NRTPRVSESE IILEDNQLWE PLYDCYQSLI QCGMRIIANG 

       370        380        390        400        410        420 
SLLNILHRIS CFGVTLSQMD IRQESTRHTD AIAEITRYIG LGDYSQWMED DKQAFLIREL 

       430        440        450        460        470        480 
SSRRPLIPQN WTPSPETKEI LDTCKVIAQQ KQGVIACYVI SMARSASDVL AVHLLLKESG 

       490        500        510        520        530        540 
VPYHIPVVPL FETLEDLDAA EKVMTQLFNV GWYRGVINNR QMVMIGYSDS AKDAGMMAAS 

       550        560        570        580        590        600 
WAQYRAQEAL VNLTEKLGIE LTLFHGRGGT IGRGGAPAHA ALLSQPPRSL KNGLRVTEQG 

       610        620        630        640        650        660 
EMIRFKLGLP AVAVETFDLY ASAILEANLL PPPEPKPEWR TIMDELSTIS CDIYRGVVRG 

       670        680        690        700        710        720 
DKDFVPYFRS ATPEQELSKL PLGSRPAKRN PNGGVESLRA IPWIFAWMQN RLMLPAWLGA 

       730        740        750        760        770        780 
GAAIRQVIEQ GKGDIIHKMC ENWPFFSTRI GMLEMVFSKS DTWLSQQYDQ RLVKKELWYL 

       790        800        810        820        830        840 
GENLRKQLED DIQTVLSLSH QSELMSDLPW IADSIALRNI YTDPLNLLQV ELLHRFRENP 

       850        860 
EQVNPDVEQA LMITITGIAA GMRNTG 

« Hide

References

[1]"The genome sequence of Haemophilus influenzae 10810."
Crook D., Hood D., Moxon R., Bentley S.D., Aslett M., Parkhill J.
Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 10810.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FQ312006 Genomic DNA. Translation: CBW30000.1.
RefSeqYP_005179836.1. NC_016809.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBW30000; CBW30000; HIB_18150.
GeneID11770189.
KEGGhiu:HIB_18150.
PATRIC43041120. VBIHaeInf165663_1889.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Enzyme and pathway databases

BioCycHINF862964:GHI0-1873-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1X8C5_HAEI1
AccessionPrimary (citable) accession number: E1X8C5
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)