Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E1X8C5

- E1X8C5_HAEI1

UniProt

E1X8C5 - E1X8C5_HAEI1

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Haemophilus influenzae (strain 10810)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (30 Nov 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei125 – 1251UniRule annotation
    Active sitei532 – 5321UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciHINF862964:GHI0-1873-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:HIB_18150Imported
    OrganismiHaemophilus influenzae (strain 10810)Imported
    Taxonomic identifieri862964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000008964: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E1X8C5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGRFLGETI NDAQGEDILE LIENIRKLSR NSRAGDDKAR QALLDTLGSI    50
    SNENIIPVAR AFSQFLNLTN IAEQYQTISR EHSLAQSSSQ SLSELFKRLK 100
    EQNASVEEVH KTVEKLLIEL VLTAHPTETT RRSLIHKHIE INKCLSKLEH 150
    HDLTEKERNI IERLLLRLIA EAWHTNEIRT VRPTPFDEAK WGFAMLENSL 200
    WQAVPEFLRQ LNETAREFLG YDLPVGLKPV RISSWMGGDR DGNPFVTAQI 250
    TKKVLYFARW KAADLFLQDI SKLADELSMM KCSDEFRDKY GEQLEPYRFV 300
    VKNLRNQLTA TLAYFDDHLS NRTPRVSESE IILEDNQLWE PLYDCYQSLI 350
    QCGMRIIANG SLLNILHRIS CFGVTLSQMD IRQESTRHTD AIAEITRYIG 400
    LGDYSQWMED DKQAFLIREL SSRRPLIPQN WTPSPETKEI LDTCKVIAQQ 450
    KQGVIACYVI SMARSASDVL AVHLLLKESG VPYHIPVVPL FETLEDLDAA 500
    EKVMTQLFNV GWYRGVINNR QMVMIGYSDS AKDAGMMAAS WAQYRAQEAL 550
    VNLTEKLGIE LTLFHGRGGT IGRGGAPAHA ALLSQPPRSL KNGLRVTEQG 600
    EMIRFKLGLP AVAVETFDLY ASAILEANLL PPPEPKPEWR TIMDELSTIS 650
    CDIYRGVVRG DKDFVPYFRS ATPEQELSKL PLGSRPAKRN PNGGVESLRA 700
    IPWIFAWMQN RLMLPAWLGA GAAIRQVIEQ GKGDIIHKMC ENWPFFSTRI 750
    GMLEMVFSKS DTWLSQQYDQ RLVKKELWYL GENLRKQLED DIQTVLSLSH 800
    QSELMSDLPW IADSIALRNI YTDPLNLLQV ELLHRFRENP EQVNPDVEQA 850
    LMITITGIAA GMRNTG 866
    Length:866
    Mass (Da):98,517
    Last modified:November 30, 2010 - v1
    Checksum:iAC260237A99A07CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312006 Genomic DNA. Translation: CBW30000.1.
    RefSeqiYP_005179836.1. NC_016809.1.

    Genome annotation databases

    EnsemblBacteriaiCBW30000; CBW30000; HIB_18150.
    GeneIDi11770189.
    KEGGihiu:HIB_18150.
    PATRICi43041120. VBIHaeInf165663_1889.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312006 Genomic DNA. Translation: CBW30000.1 .
    RefSeqi YP_005179836.1. NC_016809.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBW30000 ; CBW30000 ; HIB_18150 .
    GeneIDi 11770189.
    KEGGi hiu:HIB_18150.
    PATRICi 43041120. VBIHaeInf165663_1889.

    Phylogenomic databases

    KOi K01595.

    Enzyme and pathway databases

    BioCyci HINF862964:GHI0-1873-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Haemophilus influenzae 10810."
      Crook D., Hood D., Moxon R., Bentley S.D., Aslett M., Parkhill J.
      Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 10810Imported.

    Entry informationi

    Entry nameiE1X8C5_HAEI1
    AccessioniPrimary (citable) accession number: E1X8C5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3