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E1X754 (E1X754_HAEI1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2 EMBL CBW29577.1
Gene names
Ordered Locus Names:HIB_13900
OrganismHaemophilus influenzae (strain 10810) [Complete proteome] [HAMAP] EMBL CBW29577.1
Taxonomic identifier862964 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›

Protein attributes

Sequence length553 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Contains 2 lipoyl-binding domains. RuleBase RU000447

Ontologies

Keywords
   DomainLipoyl SAAS SAAS003016 RuleBase RU000447
   LigandPyruvate EMBL CBW29577.1
   Molecular functionAcyltransferase RuleBase RU003765
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: InterPro

   Cellular_componentpyruvate dehydrogenase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functiondihydrolipoyllysine-residue acetyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
E1X754 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: E14013405502D0E7

FASTA55358,004
        10         20         30         40         50         60 
MSKQIQIPDI GSDEVTVTEV MVNVGDTISV DQSIINVEGD KASMEVPAPE AGVVKEILVK 

        70         80         90        100        110        120 
VGDKVSTGTP MLVLEAAGAA PAADEPTAPV ADAPTAPVVA TAPTASAIVE VNVPDIGGDE 

       130        140        150        160        170        180 
VNVTEIMVAV GDTITEEQSL ITVEGDKASM EVPAPFGGVV KEILVKSGDK VSTGSLIMRF 

       190        200        210        220        230        240 
EVLGAAPAES ASASTSAPQA AAPATTAQAP QAAAPDTTAQ AAQSNNNVSG LSQEQVEAST 

       250        260        270        280        290        300 
GYAHATPVIR RLAREFGVNL DKVKGTGRKG RIVKEDIEAY VKTAVKAYES GATAQATGNG 

       310        320        330        340        350        360 
VANGAGLGLL PWPKVDFSKF GEIEEVELSR INKISGANLH RNWVIIPHVT HFDKADITDL 

       370        380        390        400        410        420 
EAFRKEQNAL AEKQKLGVKI TPVVFIMKAV AKALEAYPRF NSSITEDAQR LILKKYINIG 

       430        440        450        460        470        480 
VAVDTPNGLV VPVFKNVNKK GIIELSRELM EVSKKAREGK LTASDMQGGC FTISSLGGIG 

       490        500        510        520        530        540 
TTHFAPIVNA PEVAILGVSK SSMEPVWNGK EFAPRLILPM SLSFDHRVID GADGARFISY 

       550 
LGSVLADLRR LVM

« Hide

References

[1]"The genome sequence of Haemophilus influenzae 10810."
Crook D., Hood D., Moxon R., Bentley S.D., Aslett M., Parkhill J.
Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 10810.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FQ312006 Genomic DNA. Translation: CBW29577.1.
RefSeqYP_005179415.1. NC_016809.1.

3D structure databases

ProteinModelPortalE1X754.
SMRE1X754. Positions 1-80, 108-186, 310-553.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBW29577; CBW29577; HIB_13900.
GeneID11769762.
KEGGhiu:HIB_13900.
PATRIC43040215. VBIHaeInf165663_1441.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00627.

Family and domain databases

Gene3D3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR006256. AcTrfase_Pyrv_DH_cplx.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 2 hits.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMSSF47005. E3_bd. 1 hit.
SSF51230. Hybrid_motif. 2 hits.
TIGRFAMsTIGR01348. PDHac_trf_long. 1 hit.
PROSITEPS50968. BIOTINYL_LIPOYL. 2 hits.
PS00189. LIPOYL. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1X754_HAEI1
AccessionPrimary (citable) accession number: E1X754
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: May 1, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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