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Protein

Xylose isomerase

Gene

xylA

Organism
Haemophilus influenzae (strain 10810)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciHINF862964:GHI0-1320-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:HIB_12710Imported
OrganismiHaemophilus influenzae (strain 10810)Imported
Taxonomic identifieri862964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000008964 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliE1X6T5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01805.
OMAiHTFQHEL.
OrthoDBiPOG091H07LC.

Family and domain databases

HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiView protein in InterPro
IPR036237. Xyl_isomerase-like_sf.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
PANTHERiPTHR32176:SF0. PTHR32176:SF0. 1 hit.
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiView protein in PROSITE
PS51415. XYLOSE_ISOMERASE. 1 hit.

Sequencei

Sequence statusi: Complete.

E1X6T5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTYFDKIEK ISFEGEKSTN PFAFKHYDAN QVILGKTMAE HLRLAVCYWH
60 70 80 90 100
TFCWNGNDMF GLGSLERSWQ KNPNLLAGAE QKADIAFEFL NKLGVPYYCF
110 120 130 140 150
HDVDIAPEGN SVREYVQNFH HIVDILERKQ VETGVKLLWG TANCFTNPRY
160 170 180 190 200
MSGAATNPNP EVFAWAATQV FNAMNATQRL GGENYVLWGG REGYETLLNT
210 220 230 240 250
DLKREREQIG RFMQMVVEHK HKIGFKGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE KEIKVNIEAN HATLAGHTFQ HEIATACALD IFGSIDANRG
310 320 330 340 350
DPQLGWDTDQ FPNSVEENTL VMYEILKHGG FTTGGFNFDA KIRRQSIDPY
360 370 380 390 400
DLFYAHIGAI DVLALSLKRA AKMLQEETLQ KIVNERYAGW NSELGQHILQ
410 420 430
GKTSLETLAQ LVQQKDLAPK PVSGQQEYLE NLVNQVIYS
Length:439
Mass (Da):49,906
Last modified:November 30, 2010 - v1
Checksum:iA11651CB8D45C130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312006 Genomic DNA. Translation: CBW29458.1.
RefSeqiWP_015702065.1. NC_016809.1.

Genome annotation databases

EnsemblBacteriaiCBW29458; CBW29458; HIB_12710.
KEGGihiu:HIB_12710.
PATRICifig|862964.3.peg.1318.

Similar proteinsi

Entry informationi

Entry nameiE1X6T5_HAEI1
AccessioniPrimary (citable) accession number: E1X6T5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 25, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported