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E1X6T5

- E1X6T5_HAEI1

UniProt

E1X6T5 - E1X6T5_HAEI1

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Protein

Xylose isomerase

Gene

xylA

Organism
Haemophilus influenzae (strain 10810)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Note: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011UniRule annotation
Active sitei104 – 1041UniRule annotation
Metal bindingi232 – 2321Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 2UniRule annotation
Metal bindingi271 – 2711Magnesium 2UniRule annotation
Metal bindingi296 – 2961Magnesium 1UniRule annotation
Metal bindingi307 – 3071Magnesium 2UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi339 – 3391Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciHINF862964:GHI0-1323-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:HIB_12710Imported
OrganismiHaemophilus influenzae (strain 10810)Imported
Taxonomic identifieri862964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000008964: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliE1X6T5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1X6T5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTYFDKIEK ISFEGEKSTN PFAFKHYDAN QVILGKTMAE HLRLAVCYWH
60 70 80 90 100
TFCWNGNDMF GLGSLERSWQ KNPNLLAGAE QKADIAFEFL NKLGVPYYCF
110 120 130 140 150
HDVDIAPEGN SVREYVQNFH HIVDILERKQ VETGVKLLWG TANCFTNPRY
160 170 180 190 200
MSGAATNPNP EVFAWAATQV FNAMNATQRL GGENYVLWGG REGYETLLNT
210 220 230 240 250
DLKREREQIG RFMQMVVEHK HKIGFKGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE KEIKVNIEAN HATLAGHTFQ HEIATACALD IFGSIDANRG
310 320 330 340 350
DPQLGWDTDQ FPNSVEENTL VMYEILKHGG FTTGGFNFDA KIRRQSIDPY
360 370 380 390 400
DLFYAHIGAI DVLALSLKRA AKMLQEETLQ KIVNERYAGW NSELGQHILQ
410 420 430
GKTSLETLAQ LVQQKDLAPK PVSGQQEYLE NLVNQVIYS
Length:439
Mass (Da):49,906
Last modified:November 30, 2010 - v1
Checksum:iA11651CB8D45C130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312006 Genomic DNA. Translation: CBW29458.1.
RefSeqiYP_005179296.1. NC_016809.1.

Genome annotation databases

EnsemblBacteriaiCBW29458; CBW29458; HIB_12710.
GeneIDi11769643.
KEGGihiu:HIB_12710.
PATRICi43039967. VBIHaeInf165663_1318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312006 Genomic DNA. Translation: CBW29458.1 .
RefSeqi YP_005179296.1. NC_016809.1.

3D structure databases

ProteinModelPortali E1X6T5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBW29458 ; CBW29458 ; HIB_12710 .
GeneIDi 11769643.
KEGGi hiu:HIB_12710.
PATRICi 43039967. VBIHaeInf165663_1318.

Phylogenomic databases

KOi K01805.

Enzyme and pathway databases

BioCyci HINF862964:GHI0-1323-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Haemophilus influenzae 10810."
    Crook D., Hood D., Moxon R., Bentley S.D., Aslett M., Parkhill J.
    Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 10810Imported.

Entry informationi

Entry nameiE1X6T5_HAEI1
AccessioniPrimary (citable) accession number: E1X6T5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: November 26, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3