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E1X6T5

- E1X6T5_HAEI1

UniProt

E1X6T5 - E1X6T5_HAEI1

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Protein
Xylose isomerase
Gene
xylA, HIB_12710
Organism
Haemophilus influenzae (strain 10810)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011 By similarityUniRule annotation
Active sitei104 – 1041 By similarityUniRule annotation
Metal bindingi232 – 2321Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 2 By similarityUniRule annotation
Metal bindingi271 – 2711Magnesium 2 By similarityUniRule annotation
Metal bindingi296 – 2961Magnesium 1 By similarityUniRule annotation
Metal bindingi307 – 3071Magnesium 2 By similarityUniRule annotation
Metal bindingi309 – 3091Magnesium 2 By similarityUniRule annotation
Metal bindingi339 – 3391Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciHINF862964:GHI0-1323-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:HIB_12710Imported
OrganismiHaemophilus influenzae (strain 10810)Imported
Taxonomic identifieri862964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000008964: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliE1X6T5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1X6T5-1 [UniParc]FASTAAdd to Basket

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MTTYFDKIEK ISFEGEKSTN PFAFKHYDAN QVILGKTMAE HLRLAVCYWH    50
TFCWNGNDMF GLGSLERSWQ KNPNLLAGAE QKADIAFEFL NKLGVPYYCF 100
HDVDIAPEGN SVREYVQNFH HIVDILERKQ VETGVKLLWG TANCFTNPRY 150
MSGAATNPNP EVFAWAATQV FNAMNATQRL GGENYVLWGG REGYETLLNT 200
DLKREREQIG RFMQMVVEHK HKIGFKGTLL IEPKPQEPTK HQYDYDVATV 250
YGFLKQFGLE KEIKVNIEAN HATLAGHTFQ HEIATACALD IFGSIDANRG 300
DPQLGWDTDQ FPNSVEENTL VMYEILKHGG FTTGGFNFDA KIRRQSIDPY 350
DLFYAHIGAI DVLALSLKRA AKMLQEETLQ KIVNERYAGW NSELGQHILQ 400
GKTSLETLAQ LVQQKDLAPK PVSGQQEYLE NLVNQVIYS 439
Length:439
Mass (Da):49,906
Last modified:November 30, 2010 - v1
Checksum:iA11651CB8D45C130
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312006 Genomic DNA. Translation: CBW29458.1.
RefSeqiWP_015702065.1. NC_016809.1.
YP_005179296.1. NC_016809.1.

Genome annotation databases

EnsemblBacteriaiCBW29458; CBW29458; HIB_12710.
GeneIDi11769643.
KEGGihiu:HIB_12710.
PATRICi43039967. VBIHaeInf165663_1318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312006 Genomic DNA. Translation: CBW29458.1 .
RefSeqi WP_015702065.1. NC_016809.1.
YP_005179296.1. NC_016809.1.

3D structure databases

ProteinModelPortali E1X6T5.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBW29458 ; CBW29458 ; HIB_12710 .
GeneIDi 11769643.
KEGGi hiu:HIB_12710.
PATRICi 43039967. VBIHaeInf165663_1318.

Phylogenomic databases

KOi K01805.

Enzyme and pathway databases

BioCyci HINF862964:GHI0-1323-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Haemophilus influenzae 10810."
    Crook D., Hood D., Moxon R., Bentley S.D., Aslett M., Parkhill J.
    Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 10810.

Entry informationi

Entry nameiE1X6T5_HAEI1
AccessioniPrimary (citable) accession number: E1X6T5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: September 3, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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