E1WY06 (E1WY06_BACMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase HAMAP-Rule MF_01201
EC=5.1.1.1 HAMAP-Rule MF_01201

Gene names

Name:	alr EMBL CBW27561.1
Ordered Locus Names:	BMS_2785 EMBL CBW27561.1

Organism

Bacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ) [Complete proteome] [HAMAP] EMBL CBW27561.1

Taxonomic identifier

862908 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Bdellovibrionales › Bacteriovoracaceae › Bacteriovorax › Bacteriovorax marinus

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201
Catalytic activity	L-alanine = D-alanine. HAMAP-Rule MF_01201
Cofactor	Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS000821
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201
Sequence similarities	Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate HAMAP-Rule MF_01201 SAAS SAAS000821
Molecular function	Isomerase SAAS SAAS000821 HAMAP-Rule MF_01201
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	alanine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	35	1	Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
	Active site	271	1	Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
	Binding site	137	1	Substrate By similarity HAMAP-Rule MF_01201
	Binding site	317	1	Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201
Amino acid modifications
	Modified residue	35	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

	Sequence		Length	Mass (Da)
	E1WY06 [UniParc]. Last modified November 30, 2010. Version 1. Checksum: D13D3306B5D76302	FASTA	375	42,675
	10 20 30 40 50 60 MRFRSRHFIS FEKLENNYKK LKEICVDNKI IFMVKANAYG HGVIPIVRHS VEKLGITEFG 70 80 90 100 110 120 CASLGEALLL REELYDLEFE IYVFSDVQVE LRECAEIYLN RRIIPVISNR DDLDFILNSR 130 140 150 160 170 180 EFENFPLFIK FNTGMNRLGL EMDKVDEVIR SIRVSGRKSI YHLMTHLSSS SLPIKKNKRN 190 200 210 220 230 240 IIQFENFEKI KKAFSDAGIE VERTSIANSG AIEQGAGLGE THVRPGLMMY GPSSMLPQYS 250 260 270 280 290 300 DLSLWSGEII SKLETYVISI FDVEKGQPVG YGATPCPSKG KVAIVALGYG DGFTTRYIGT 310 320 330 340 350 360 HLYHKDIKGK VVGRVNMDMA QVFFDENSLP DLKVGDSFTL WDHSAERFAE FCKEAKIIPY 370 EVFIGITQRV PKIYS

References

[1]	"The genome sequence of Bacteriovorax marinus SJ." Stine O.C., Williams H.N., Pineiro S., Bentley S.D., Parkhill J. Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-682 / DSM 15412 / SJ.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FQ312005 Genomic DNA. Translation: CBW27561.1.
RefSeq	YP_005036519.1. NC_016620.1.
3D structure databases
ProteinModelPortal	E1WY06.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBW27561; CBW27561; BMS_2785.
GeneID	11550197.
KEGG	bmx:BMS_2785.
PATRIC	42741533. VBIBacMar168520_2661.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
BioCyc	BMAR862908:GJBX-2648-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E1WY06_BACMS

Accession

Primary (citable) accession number: E1WY06

Entry history

Integrated into UniProtKB/TrEMBL:	November 30, 2010
Last sequence update:	November 30, 2010
Last modified:	May 29, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)