ID   E1WMX5_BACF6            Unreviewed;       529 AA.
AC   E1WMX5;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Putative sialidase {ECO:0000313|EMBL:CBW24233.1};
GN   OrderedLocusNames=BF638R_3784 {ECO:0000313|EMBL:CBW24233.1};
OS   Bacteroides fragilis (strain 638R).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=862962 {ECO:0000313|EMBL:CBW24233.1, ECO:0000313|Proteomes:UP000008560};
RN   [1] {ECO:0000313|EMBL:CBW24233.1, ECO:0000313|Proteomes:UP000008560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638R {ECO:0000313|EMBL:CBW24233.1,
RC   ECO:0000313|Proteomes:UP000008560};
RX   PubMed=20829291; DOI=10.1099/mic.0.042978-0;
RA   Patrick S., Blakely G.W., Houston S., Moore J., Abratt V.R., Bertalan M.,
RA   Cerdeno-Tarraga A.M., Quail M.A., Corton N., Corton C., Bignell A.,
RA   Barron A., Clark L., Bentley S.D., Parkhill J.;
RT   "Twenty-eight divergent polysaccharide loci specifying within- and amongst-
RT   strain capsule diversity in three strains of Bacteroides fragilis.";
RL   Microbiology 156:3255-3269(2010).
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DR   EMBL; FQ312004; CBW24233.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1WMX5; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; bfg:BF638R_3784; -.
DR   PATRIC; fig|862962.3.peg.3931; -.
DR   HOGENOM; CLU_024620_0_0_10; -.
DR   Proteomes; UP000008560; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR029456; Sialidase_N.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF19; SIALIDASE; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   Pfam; PF14873; BNR_assoc_N; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
FT   DOMAIN          2..124
FT                   /note="Sialidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14873"
FT   DOMAIN          166..499
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   529 AA;  58948 MW;  CC3D3A1013970F02 CRC64;
     MKVIVRQPIV PVLTKKEINP VLQLKLIKSC PGPCFVKEIG LSLKGTTLLT DLTHLSLYRV
     AGKRGLSDWE KCVDSVAPAL KTVLDTPLEL KSDTTILWVT VKLKDKVDLT HRVTVSCDHV
     TTTCGKASVT SVRPIVALRT GVAVRQRRED GVHTSRIPGI TTSLKGTLMA IFDARYDSSR
     DLQGDIDIAM MRSLDGGMSW QPMQIVLDRK KWGGLPEKYN GISDACILTD EKNGTIYVAG
     LWMYGVLDPR SGKWVEGMTQ DSTRWIHQWH AKGSQPGLGV KETCQFLITK SVDDGLTWSD
     PVNITAQTKK PEWWLYAPAP GHGITLKEGT LIFPTQGRDK DGIPFSNITY SKDGGKTWIA
     SKPAYHNTTE CMAVELQDGS VMLNMRDNRN HGNKKVNGRR ICVTSDLGST WTEHSTSRKA
     LIEPTCMASI HRHTYQENGR QKTLLLFCNP ESYDSRDHMT LKCSLDDGNT WDSGRKIMLD
     ELGSFGYSCI TSVNDSTIGV FYESSQAQMV FQQIQLKELI GKGKSYKER
//