Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E1WG39

- E1WG39_SALTS

UniProt

E1WG39 - E1WG39_SALTS

Protein

Alanine racemase

Gene

alr-a

Organism
Salmonella typhimurium (strain SL1344)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (30 Nov 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei130 – 1301SubstrateUniRule annotation
    Active sitei253 – 2531Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei301 – 3011Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciSENT216597:GJB7-1754-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alr-aImported
    Ordered Locus Names:SL1344_1730Imported
    OrganismiSalmonella typhimurium (strain SL1344)Imported
    Taxonomic identifieri216597 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000008962: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

    Proteomic databases

    PRIDEiE1WG39.

    Structurei

    3D structure databases

    ProteinModelPortaliE1WG39.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    OMAiPVELWGQ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E1WG39-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRPIQASLD LQVMKQNLAI VRRAAPEARV WSVVKANAYG HGIERVWSAL    50
    GATDGFAMLN LEEAITLRER GWKGPILMLE GFFHAQDLEA YDTYRLTTCI 100
    HSNWQLKALQ NARLNAPLDI YVKVNSGMNR LGFQPERAQT VWQQLRAMRN 150
    VGEMTLMSHF AQADHPEGIG EAMRRIALAT EGLQCAYSLS NSAATLWHPQ 200
    AHYDWVRPGI ILYGASPSGQ WRDIADTGLK PVMTLSSEII GVQTLSAGER 250
    VGYGGGYSVT QEQRIGIVAA GYADGYPRHA PTGTPVLVDG IRTRTVGTVS 300
    MDMLAVDLTP CPQAGIGTPV ELWGKEIKVD DVASAAGTLG YELLCAVAPR 350
    VPFVTT 356
    Length:356
    Mass (Da):38,804
    Last modified:November 30, 2010 - v1
    Checksum:i43DF23205EF25C69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312003 Genomic DNA. Translation: CBW17825.1.
    RefSeqiYP_005181635.1. NC_016810.1.

    Genome annotation databases

    EnsemblBacteriaiCBW17825; CBW17825; SL1344_1730.
    PATRICi43189151. VBISalEnt88447_1915.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312003 Genomic DNA. Translation: CBW17825.1 .
    RefSeqi YP_005181635.1. NC_016810.1.

    3D structure databases

    ProteinModelPortali E1WG39.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi E1WG39.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBW17825 ; CBW17825 ; SL1344_1730 .
    PATRICi 43189151. VBISalEnt88447_1915.

    Phylogenomic databases

    OMAi PVELWGQ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci SENT216597:GJB7-1754-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Salmonella enterica subsp. enterica serovar Typhimurium SL1344."
      Dougan G., Barrow P., Achtman M., Parkhill J., Thomson N.R.
      Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SL1344.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SL1344Imported.

    Entry informationi

    Entry nameiE1WG39_SALTS
    AccessioniPrimary (citable) accession number: E1WG39
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3