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E1VY23

- E1VY23_ARTAR

UniProt

E1VY23 - E1VY23_ARTAR

Protein

Alanine racemase

Gene

alr

Organism
Arthrobacter arilaitensis (strain DSM 16368 / CIP 108037 / JCM 13566 / Re117)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (30 Nov 2010)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei55 – 551Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei152 – 1521SubstrateUniRule annotation
    Active sitei285 – 2851Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei332 – 3321Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciAARI861360:GI6T-2504-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:AARI_23060Imported
    OrganismiArthrobacter arilaitensis (strain DSM 16368 / CIP 108037 / JCM 13566 / Re117)Imported
    Taxonomic identifieri861360 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
    ProteomesiUP000006878: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei55 – 551N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE1VY23.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiWELERVA.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E1VY23-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNSEALEESN LTNSTSSAQA TGFERRAVID LSAIRNNVKQ ISDVVAPAAV    50
    MAVVKADAYG HGAIQVAKAA LEGGARWIGC AHVTEALALR EAGIDAPMLA 100
    WLHTEDTPFE AAIDAGLDLG VSGWELERVA AAARAVQTPA RIHIKVDTGL 150
    GRNGSTMEAL PDLLNRASDF QEEGLLRAVG IFSHLAVADE PERPETDEQL 200
    AVFNTAIELI EAAGFDLEVR HIANTPGILS RPDSHYEMVR LGLGLYGLSP 250
    FEEDTPQSFG LRPAMTVKTR VANVKKVRPG QGVSYGLNYK TEGETYLGLI 300
    PMGYADGLPR IATGAPVTVN GRTYPVRGRI AMDQCVIDLG ADINPEDFLG 350
    AEAIIFGDGG QSVNTWAYAA NTINYEVVTR ISPRVPRYYI EGSWGEAGE 399
    Length:399
    Mass (Da):42,689
    Last modified:November 30, 2010 - v1
    Checksum:i4E26069039B3EB1E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ311875 Genomic DNA. Translation: CBT76526.1.
    RefSeqiWP_013349643.1. NC_014550.1.
    YP_003917497.1. NC_014550.1.

    Genome annotation databases

    EnsemblBacteriaiCBT76526; CBT76526; AARI_23060.
    GeneIDi9794896.
    KEGGiaai:AARI_23060.
    PATRICi42171489. VBIArtAri166201_2462.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ311875 Genomic DNA. Translation: CBT76526.1 .
    RefSeqi WP_013349643.1. NC_014550.1.
    YP_003917497.1. NC_014550.1.

    3D structure databases

    ProteinModelPortali E1VY23.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBT76526 ; CBT76526 ; AARI_23060 .
    GeneIDi 9794896.
    KEGGi aai:AARI_23060.
    PATRICi 42171489. VBIArtAri166201_2462.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi WELERVA.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci AARI861360:GI6T-2504-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Arthrobacter arilaitensis Re117 genome sequence reveals its genetic adaptation to the surface of cheese."
      Monnet C., Loux V., Gibrat J.F., Spinnler E., Barbe V., Vacherie B., Gavory F., Gourbeyre E., Siguier P., Chandler M., Elleuch R., Irlinger F., Vallaeys T.
      PLoS ONE 5:E15489-E15489(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DSM 16368 / CIP 108037 / JCM 13566 / Re117Imported.
    2. "Complete genome sequence of Arthrobacter arilaitensis (strain DSM 16368 / CIP 108037 / JCM 13566 / Re117)."
      Genoscope.
      Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 16368 / CIP 108037 / JCM 13566 / Re117Imported.

    Entry informationi

    Entry nameiE1VY23_ARTAR
    AccessioniPrimary (citable) accession number: E1VY23
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3