Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E1VK08

- E1VK08_9GAMM

UniProt

E1VK08 - E1VK08_9GAMM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
gamma proteobacterium HdN1
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciGPRO83406:GIWA-1605-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
ORF Names:HDN1F_15670Imported
Organismigamma proteobacterium HdN1Imported
Taxonomic identifieri83406 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteria
ProteomesiUP000002677: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE1VK08.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000021113.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1VK08-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGYQKIKVPA DGDKITVNAD LSLNVPNYPV IPFIEGDGIG VDITPVMLKV
60 70 80 90 100
VNAAVEKAYG TKRAISWMEV YCGEKATKVY GPDVWLPEET LDVLREYIVS
110 120 130 140 150
IKGPLTTPVG GGIRSLNVAL RQELDLYVCQ RPVRWFKGVP SPVTSPHKTD
160 170 180 190 200
MVIFRENSED IYAGIEWKAD SPEAIKIIKF LQEEMGVKKI RFTEHCGIGI
210 220 230 240 250
KPVSKEGTQR LVRKAIQYAI DNDEPSVTFV HKGNIMKYTE GAFKEWGYEL
260 270 280 290 300
AQERFGAELL DGGPWMTMKN PKTGRDIIIK DVIADAFLQQ ILMRPEEYSI
310 320 330 340 350
IATLNLNGDY ISDALAAEVG GIGIAPGANI GGSVAMFEAT HGTAPKYAGQ
360 370 380 390 400
DKVNPGSLIL SAEMMLRHMG WTEAADLIIR GMEGSIEAKT VTYDFERLMP
410
NATLLRCSEF GDALIRHME
Length:419
Mass (Da):46,291
Last modified:November 30, 2010 - v1
Checksum:iF7F69599C3EA32C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929140 Genomic DNA. Translation: CBL45150.1.
RefSeqiWP_013261644.1. NC_014366.1.
YP_003810802.1. NC_014366.1.

Genome annotation databases

EnsemblBacteriaiCBL45150; CBL45150; HDN1F_15670.
GeneIDi9700866.
KEGGigpb:HDN1F_15670.
PATRICi42346105. VBIGamPro61291_1703.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929140 Genomic DNA. Translation: CBL45150.1 .
RefSeqi WP_013261644.1. NC_014366.1.
YP_003810802.1. NC_014366.1.

3D structure databases

ProteinModelPortali E1VK08.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBL45150 ; CBL45150 ; HDN1F_15670 .
GeneIDi 9700866.
KEGGi gpb:HDN1F_15670.
PATRICi 42346105. VBIGamPro61291_1703.

Phylogenomic databases

HOGENOMi HOG000021113.
KOi K00031.

Enzyme and pathway databases

BioCyci GPRO83406:GIWA-1605-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Alkane degradation by a new type of denitrifying bacterium with possible involvement of the electron acceptor in substrate activation."
    Widdel F., Rabus R., Grundmann O., Werner I., Schreiber F., Ehrenreich P., Behrends A., Wilkes H., Kube M., Reinhardt R., Zedelius J.
    Environ. Microbiol. 0:0-0(2010)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiE1VK08_9GAMM
AccessioniPrimary (citable) accession number: E1VK08
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: November 26, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3