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E1VK08 (E1VK08_9GAMM) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CBL45150.1
ORF Names:HDN1F_15670 EMBL CBL45150.1
Organismgamma proteobacterium HdN1 EMBL CBL45150.1
Taxonomic identifier83406 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria ›

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
E1VK08 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: F7F69599C3EA32C7

FASTA41946,291
        10         20         30         40         50         60 
MGYQKIKVPA DGDKITVNAD LSLNVPNYPV IPFIEGDGIG VDITPVMLKV VNAAVEKAYG 

        70         80         90        100        110        120 
TKRAISWMEV YCGEKATKVY GPDVWLPEET LDVLREYIVS IKGPLTTPVG GGIRSLNVAL 

       130        140        150        160        170        180 
RQELDLYVCQ RPVRWFKGVP SPVTSPHKTD MVIFRENSED IYAGIEWKAD SPEAIKIIKF 

       190        200        210        220        230        240 
LQEEMGVKKI RFTEHCGIGI KPVSKEGTQR LVRKAIQYAI DNDEPSVTFV HKGNIMKYTE 

       250        260        270        280        290        300 
GAFKEWGYEL AQERFGAELL DGGPWMTMKN PKTGRDIIIK DVIADAFLQQ ILMRPEEYSI 

       310        320        330        340        350        360 
IATLNLNGDY ISDALAAEVG GIGIAPGANI GGSVAMFEAT HGTAPKYAGQ DKVNPGSLIL 

       370        380        390        400        410 
SAEMMLRHMG WTEAADLIIR GMEGSIEAKT VTYDFERLMP NATLLRCSEF GDALIRHME

« Hide

References

[1]"Alkane degradation by a new type of denitrifying bacterium with possible involvement of the electron acceptor in substrate activation."
Widdel F., Rabus R., Grundmann O., Werner I., Schreiber F., Ehrenreich P., Behrends A., Wilkes H., Kube M., Reinhardt R., Zedelius J.
Environ. Microbiol. 0:0-0(2010)
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FP929140 Genomic DNA. Translation: CBL45150.1.
RefSeqYP_003810802.1. NC_014366.1.

3D structure databases

ProteinModelPortalE1VK08.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBL45150; CBL45150; HDN1F_15670.
GeneID9700866.
KEGGgpb:HDN1F_15670.
PATRIC42346105. VBIGamPro61291_1703.

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.

Enzyme and pathway databases

BioCycGPRO83406:GIWA-1568-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1VK08_9GAMM
AccessionPrimary (citable) accession number: E1VK08
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: April 3, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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